Protein Alignment Klp64D and Klp67A

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_523992.2
• Gene: Klp67A / 39068
• FlyBaseID: FBgn0004379
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 774
• Identity: 217/774 - (28%)
• Similarity: 344/774 - (44%)
• Gaps: 158/774 - (20%)

  Fly     1 MPQEEANAGTTAQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNAT----- 60
            ||.|:..            |::|.||.||.:..||.....|.|.|  ::|:..:..|:..
  Fly     1 MPSEQHT------------NIKVAVRVRPYNVRELEQKQRSIIKV--MDRSALLFDPDEEDDEFF 51

  Fly    61 ---ANEPPK----------TYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTG 112
               |.:|.:          |..||.|||..::..||:.:...|:||.||.|||.::..||.||.|
  Fly    52 FQGAKQPYRDITKRMNKKLTMEFDRVFDIDNSNQDLFEECTAPLVDAVLNGYNCSVFVYGATGAG 116

  Fly   113 KTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLE 177
            ||:||.|:...|   |:.......:|..|....:.:||.|.|||:|:|||.|.:||    .||..
  Fly   117 KTFTMLGSEAHP---GLTYLTMQDLFDKIQAQSDVRKFDVGVSYLEVYNEHVMNLL----TKSGP 174

  Fly   178 VKERPD-IGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELG 241
            :|.|.| .||.|..|....:::|::|..::.|||.:|....|..|.|||||||||.:.:   .:.
  Fly   175 LKLREDNNGVVVSGLCLTPIYSAEELLRMLMLGNSHRTQHPTDANAESSRSHAIFQVHI---RIT 236

  Fly   242 EGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRN 306
            |......|..||.::|||||||.:.|:..|.|.||...||.||..|||.|:.|.||.. |||||:
  Fly   237 ERKTDTKRTVKLSMIDLAGSERAASTKGIGVRFKEGASINKSLLALGNCINKLADGLK-HIPYRD 300

  Fly   307 SKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHIN----EEPKDALL 367
            |.|||:|:||||||.:|:|.|.:|.:...|.:|.:||:||||||.|:..:..|    :.|.:..:
  Fly   301 SNLTRILKDSLGGNCRTLMVANVSMSSLTYEDTYNTLKYASRAKKIRTTLKQNVLKSKMPTEFYV 365

  Fly   368 RHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKT 432
            :...|.:|...:..|...:||.:....|...::..|    |||::...|.|.||....::.:|..
  Fly   366 KKIDEVVAENERLKERNKALEAKATQLERAGNSGFD----PLELKTWYSKIDAVYAAARQLQEHV 426

  Fly   433 DAEKEELAKRKNEHQ---KEIEHAK-------------------------TEQETLRNKLVSLEG 469
            ...:.:: |..|..|   ||:|..:                         ::.|..:.:|.|...
  Fly   427 LGMRSKI-KNINYRQTLKKELEEFRKLMCVDQRVCQEDFRRFANYMSTLTSQMEKYKEELPSWLS 490

  Fly   470 KILVGGENL------LEKAQTQELLLEQSIAELEQHEKSEEALKQ--------TLQQKATERID- 519
            |:.:..::|      :.|::..::|    |..::..:...:..||        .:.|:..|.:|
  Fly   491 KMEIAYQDLESLKREVNKSKAYQIL----IVYVKYKDLELQLTKQNIFNNHVNAINQELVENLDL 551

  Fly   520 -----------IEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKE---GIYENI 570
                       :.:.|..|:|... :|.:|..|.:.|:. |...||.:...:..:.   .:...:
  Fly   552 MRKSFRTACEVLNQTYDRLEDGQK-LTPEIEAVFERLLR-KMRFADSEANTKMAEMNPLAVPVAL 614

  Fly   571 RSLSR--ELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHIS------- 626
            ||.::  |...|.|..::   |:.|   .|....::|:                 |:|
  Fly   615 RSSAQEEEEPTCSLTASA---KKRQ---RQAAQSDDDL-----------------HLSMEDFDSQ 656

  Fly   627 --------AHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARPR-TSGVPRPTTARR 676
                    .|:|. |.|..|:.:.|....::...|:...|.|||.. |:.|.:|.|.::
  Fly   657 DTESDSEELHRTF-KRPRNLNETQVLGPCSSSSSSSTSSSSSARKALTATVTKPRTVQQ 714

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	141/351 (40%)
		Smc	<433..>578	CDD:440809	32/203 (16%)
Klp67A	NP_523992.2	KISc_KIP3_like	8..346	CDD:276821	141/350 (40%)