Protein Alignment Klp64D and Khc-73

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001261000.1
• Gene: Khc-73 / 36718
• FlyBaseID: FBgn0019968
• Length: 1957
• Species: Drosophila melanogaster
• Alignment Length: 653
• Identity: 207/653 - (31%)
• Similarity: 312/653 - (47%)
• Gaps: 133/653 - (20%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKP-NATANEPPKTYYFDNVF-------D 75
            :.::|.||.||.::.|:.......:.::|....:....| .....:.|||:.||:.|       :
  Fly     4 DKIKVAVRVRPFNRREIELDTKCIVEMEKQQTILQNPPPLEKIERKQPKTFAFDHCFYSLNPEDE 68

  Fly    76 GGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGH 140
            ..::|..::....|.|:|...:|||..|.||||||:||:|||.|..:|   |||||.....:|..
  Fly    69 NFASQETVFDCVGRGILDNAFQGYNACIFAYGQTGSGKSYTMMGTQES---KGIIPRLCDQLFSA 130

  Fly   141 IA-KAKENQKFLVRVSYMEIYNEEVRDLLGKDVGK-SLEVKERPDIGVFVKDLSGYVVHNADDLE 203
            || |:.....:.|.|||||||||:|.|||.....| ||:|:|...:|.:|..||...|.:..|::
  Fly   131 IANKSTPELMYKVEVSYMEIYNEKVHDLLDPKPNKQSLKVREHNVMGPYVDGLSQLAVTSYQDID 195

  Fly   204 NIMRLGNKNRAVGATKMNQESSRSHAIFSITVER--SELGEGDVQHVRMGKLQLVDLAGSERQSK 266
            |:|..|||:|.|.||.||.|||||||:||:.:.:  ::...| |...::.::.|||||||||..|
  Fly   196 NLMTEGNKSRTVAATNMNAESSRSHAVFSVVLTQILTDQATG-VSGEKVSRMSLVDLAGSERAVK 259

  Fly   267 TQASGQRLKEATKINLSLSVLGNVISALVD-------GKSTHIPYRNSKLTRLLQDSLGGNSKTV 324
            |.|.|.||||.:.||.||:.||.|||.|.|       |....:|||:|.||.||:|:|||||:||
  Fly   260 TGAVGDRLKEGSNINKSLTTLGLVISKLADQSNGKKSGNDKFVPYRDSVLTWLLKDNLGGNSRTV 324

  Fly   325 MCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLE------- 382
            |.|||||:..||.||:||||||.|||.|.|...:||:|...::|..:.|:..||..|:
  Fly   325 MVATISPSADNYEETLSTLRYADRAKRIVNHAVVNEDPNARIIRELRHEVETLRSMLKHATGSPV 389

  Fly   383 --------EGDSLEEEPPSSEEEE----DTADDELEAPLE---IELESSTIQAVEKKPKKKREKT 432
                    |.::|.::...:.||:    :...:|.:..||   |.:::|.|:..:.|........
  Fly   390 GDVQDKLAESENLMKQISQTWEEKLVKTERIQNERQQALEKMGISVQASGIKVEKNKYYLVNLNA 454

  Fly   433 DAEKEEL------------AKRKNEHQKEI---------EHAKTEQETLRNKLVSLEG-KILVGG 475
            |....||            .:..:..|.:|         ||.....|.....:..::| :..|.|
  Fly   455 DPSLNELLVYYLKDRTLIGGRTISGQQPDIQLSGLGIQPEHCVITIEDSGLYMEPVQGARCFVNG 519

  Fly   476 ENLLEKA---------------------------------QTQELLLEQSIA--ELEQHEKSEEA 505
            ...:||.                                 ||...|::.:.|  |:.|:|.|.:.
  Fly   520 SAAVEKTPLQNGDRILWGNHHFFRVNSPKSNNTSMCASEPQTPAQLIDYNFARDEIMQNELSNDP 584

  Fly   506 LKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENI 570
            :     |.|..|::.:..    :|....:.|                  |:||::|:    ::.:
  Fly   585 I-----QTAIARLERQHE----EDKQVALEK------------------QRQEYERQ----FQQL 618

  Fly   571 RSL 573
            |::
  Fly   619 RNI 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	155/351 (44%)
		Smc	<433..>578	CDD:440809	31/198 (16%)
Khc-73	NP_001261000.1	KISc_KIF1A_KIF1B	4..359	CDD:276816	157/358 (44%)
		Kinesin_assoc	356..468	CDD:465047	22/111 (20%)
		FHA_KIF13	446..547	CDD:438758	14/100 (14%)
		KIF1B	741..786	CDD:463574
		DUF3694	989..1243	CDD:463599
		CAP_GLY	1785..1850	CDD:460154