Protein Alignment Klp64D and Kif14

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001414162.1
• Gene: Kif14 / 360849
• RGDID: 1310650
• Length: 1672
• Species: Rattus norvegicus
• Alignment Length: 751
• Identity: 224/751 - (29%)
• Similarity: 334/751 - (44%)
• Gaps: 198/751 - (26%)

  Fly     2 PQEEANAGTTAQLDD--EIEN--VRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATAN 62
            |:|::....|....|  ::||  |.|.||.||..|.|.:..|...  |.:....|||..|:.
  Rat   371 PEEKSTVQNTFTEPDSLKVENSQVTVAVRVRPFSKREKTEKASQV--VFRNGEEITVEHPDM--- 430

  Fly    63 EPPKTYY----------FDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTM 117
               |..|          ||....|.:||..:|...|.|::|:..||||..:.||||||:||:|||
  Rat   431 ---KQIYSFIYDVAFWSFDECHPGYANQTTVYETLAAPLLDRAFEGYNTCLFAYGQTGSGKSYTM 492

  Fly   118 SGNPDSPQTKGIIPNAFAHIFGHIAKAKENQ-KFLVRVSYMEIYNEEVRDLL---GKDVGKS--L 176
            .|..:.|   ||||.....:|..|||.:.:: .:.:.:|:.|:|||::.|||   |::..:.  |
  Rat   493 MGLNEEP---GIIPRFCEDLFAQIAKKQASEVSYHLEMSFFEVYNEKIHDLLVCKGENGQRKQPL 554

  Fly   177 EVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSI--TVERSE 239
            .|:|.|..|.:|:.||..||.:..|:::.:.||||.||..||.||.:|||||::|::  |..::|
  Rat   555 RVREHPVSGPYVEGLSMNVVSSYSDIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTE 619

  Fly   240 LGEGDVQHVRM-GKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISAL---VDGKST 300
            ..||:....|: .::.|:|||||||.|...:||:||||...||.||..||.|||||   .:||..
  Rat   620 FVEGEEHDHRITSRINLIDLAGSERCSTAHSSGERLKEGVSINKSLLTLGKVISALSEQANGKRV 684

  Fly   301 HIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDA 365
            .||||.|.||.||::||||||||.|.||||||.||..||:||||||::|:.|.|...:||:....
  Rat   685 FIPYRESTLTWLLKESLGGNSKTAMIATISPAASNIEETLSTLRYATQARLIVNVAKVNEDMNAK 749

  Fly   366 LLRHFQEEIARLR---------------------------------------------------- 378
            |:|..:.||.:|:
  Rat   750 LIRELKAEIEKLKAAQKSSRNIDPERYRLCRQEISSLRMKLHQQERDMAEIQRVWKEKFEQAEKR 814

  Fly   379 -----KQLEEGD-------------SLEEEPPSSE------EEEDT------------------- 400
                 |:|::..             :|.|:|..||      :|..|
  Rat   815 KLQETKELQKAGVTFQMDNHLPNLVNLNEDPQLSEMLLYMVKEGITTVGKHTPNSSHDIQLSGVL 879

  Fly   401 -ADDEL---------------EAPLEI---ELESSTI------------------QAVEKKPKKK 428
             |||..               ||...:   .:...|:                  ..||.:..||
  Rat   880 IADDHCTIRSYGGTVSIVPAGEAKTYVNGMHISEPTVLHHGDRVVLGGDHYFRFNHPVEVQKGKK 944

  Fly   429 REKTD-----------AEKEELAKRKNEHQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKA 482
            ..:.:           |:.|.||.:::..:.||:.|:     |:.|...::| |.:..|...::.
  Rat   945 TSRNNLTSEGPKDFEFAKNELLAAQRSRLEAEIKDAQ-----LKAKEEMMQG-IQIAKEMAQQEL 1003

  Fly   483 QTQELLLEQSIAELE---QHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQM 544
            .:|....|..|..||   :.|...:.|::...|||:.:|:..|:.....:....:.|:  |:...
  Rat  1004 SSQRAAYENKIRALEAELREESQRKRLEEINNQKASHKIEELEKAKQHLEQEVYVNKR--RLEME 1066

  Fly   545 LMGVKSELADQQQEH-------QREKEGIYENIRSL 573
            .:..|..|.|.:..|       :|||:.|.|.::.|
  Rat  1067 TLATKQALEDHRIRHARILEALEREKQKIAEEVQIL 1102

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	156/356 (44%)
		Smc	<433..>578	CDD:440809	36/162 (22%)
Kif14	NP_001414162.1	None