Protein Alignment Klp64D and kif20a

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001154942.2
• Gene: kif20a / 325449
• ZFINID: ZDB-GENE-050522-252
• Length: 921
• Species: Danio rerio
• Alignment Length: 808
• Identity: 191/808 - (23%)
• Similarity: 310/808 - (38%)
• Gaps: 277/808 - (34%)

  Fly     3 QEEANAGTTAQLDDEIENVRVVVRTRPM-----DKNELSAGALSAISVDKINRAITVMKPNATAN 62
            |.:::.......||..:.::|.:|.||:     |:.| ..|.::..|.|.    :.:..|..:.|
Zfish    61 QIKSDISRRGSTDDGSDKLKVFLRIRPLTEAEKDRGE-EQGCVNVQSEDN----LLLKAPKDSRN 120

  Fly    63 ---------EPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMS 118
                     :....:.|..:|...::|.::|..|.|.:|..||.|.|..:..||.|.:|||||:.
Zfish   121 MKSAERGVAQSVHKFTFTKIFGPQTSQQEVYDHTIREMVRDVLRGENRLLYTYGVTNSGKTYTIQ 185

  Fly   119 GNPDSPQTKGIIPNAFAHIF--------------------------------------------- 138
            |   :....|::|.|...:|
Zfish   186 G---AGAEAGLLPRALVSVFLKLSGRLYTAMDLKPVLSQEVRKLDVGEVRAEEMRRDALLKEDES 247

  Fly   139 ---------------------GHIA----------------------KAKENQKFLVRVSYMEIY 160
                                 .|||                      ..:|..:|.|.||:.|||
Zfish   248 NQSRLRAGLSWDSGISGLSATSHIATQLEDSDGVCLEANGLCLSGGEDLEEGVQFSVWVSFYEIY 312

  Fly   161 NEEVRDLLGKDVGKSLEVKERPDIGV--------FVKDLSGYVVHNADDLENIMRLGNKNRAVGA 217
            ||.:.|||  |...||:.::|..:.:        :||||:...||:|::...::::|.:|::..:
Zfish   313 NEFLYDLL--DAPPSLQSRKRVTLRLSDDKHGNPYVKDLTWIQVHSAEEAWKVLKVGQRNQSFAS 375

  Fly   218 TKMNQESSRSHAIFSITV--ERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKI 280
            |.:|..|||||:||:|.|  .:.:||    |..|:.:|.:.||||||| .|.|.:|:|:|||..|
Zfish   376 THLNHNSSRSHSIFTIRVLHVKPQLG----QVTRISELSVCDLAGSER-CKAQQNGERMKEANNI 435

  Fly   281 NLSLSVLGNVISALVDGKSTH------IPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMET 339
            |.||..||..|:||...::..      :|:|:|||||:||....|:.::.|...|:|..|.|.||
Zfish   436 NTSLLTLGRCITALRHNQTNKSRPPVVVPFRDSKLTRVLQSFFCGHGRSCMVVNINPCASTYDET 500

  Fly   340 ISTLRYASRAKNI------------------QNRMHIN--------EEPKD-----------ALL 367
            :..|::::.|..:                  :...|.|        ||..|           |||
Zfish   501 LQALKFSAIATQLVHGPCSKTRVAYILSLLREQPTHPNDTTLLEEDEEESDEEGDITMFDPEALL 565

  Fly   368 RH---FQEEIARLRKQLEEGDSLEEEPPSSEEEE--DTADDELEAPLEIE--------------L 413
            :.   .:.|:.|.|::.||.::...|...:|..|  ....|:....||.|              |
Zfish   566 KAIDVLKREVLRQRQEKEELEAKVREEVCTEMMEVISRMQDDFSETLESERDLMEKRCENKINNL 630

  Fly   414 ESST----IQAVEKKPKKKREKTDAEKEELA----------------------------KRKNEH 446
            :||.    .|.:|::..:.||.|.|.||:.|                            ||..:|
Zfish   631 KSSLKKYYSQELEERDDEIRELTAALKEKEAGNTAPVAIFPPLNDDGGLRRSQRLASTHKRDADH 695

  Fly   447 QK--------EIEHAKTE----QETLRNKLVSLE------------GKILVGGENLLEKAQ--TQ 485
            :.        |:|:.:.|    |..||.|.:.|:            |.:....|..||:.|  .:
Zfish   696 ESIELFRCKAELENCRAELDLKQTELRLKTLELKRFQDNLPSMGVTGTLTTTAERKLEEGQRNLK 760

  Fly   486 ELLLEQSIAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDASTGITK------KIHRVMQM 544
            :|.:|..:..::.........:.|         |.|:....|..|.:.:.|      ::|..:|:
Zfish   761 QLRMELQLLGIKLQSGERACCRNT---------DGEKLRHALSSADSKLAKQDQMLVELHTSLQL 816

  Fly   545 LMGVKSEL------------ADQQQEHQ 560
               ||:||            ..|.|.||
Zfish   817 ---VKAELRKKDELLTRFQNTQQAQSHQ 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	122/450 (27%)
		Smc	<433..>578	CDD:440809	38/200 (19%)
kif20a	NP_001154942.2	None