Protein Alignment Klp64D and Kif12

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_006238315.1
• Gene: Kif12 / 313254
• RGDID: 1308487
• Length: 648
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 157/483 - (32%)
• Similarity: 239/483 - (49%)
• Gaps: 67/483 - (13%)

  Fly    21 VRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDLY- 84
            ::||:|.|||...||..|..||:.... .|.:.|..|   ...|...:.|..|.||...|.|::
  Rat    26 IQVVLRVRPMSTVELRRGEQSALHCSG-TRTLQVSPP---GGGPDVAFRFGAVLDGARTQEDVFR 86

  Fly    85 VDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGI-IPNAFAHI----------- 137
            ....:.:.:..|.|::.|:..:||||:|||||::|.|  ||.:|: :|.:.|.|
  Rat    87 ACGVKRLGELALRGFSCTVFTFGQTGSGKTYTLTGPP--PQAEGVPVPPSLAGIMQRTFTWLLDR 149

  Fly   138 FGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDL 202
            ..|:     :....:|.||:|||||:|:|||.:...:.|.|:.....|.:|:.|......:.:.|
  Rat   150 MQHL-----DSPVTLRASYLEIYNEQVQDLLSQGSPRPLPVRWSKARGFYVEQLRLVECGSLEAL 209

  Fly   203 ENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERS--------ELGEGDVQHVRMGKLQLVDLA 259
            ..::::|...|...:..:||.||||||:.::.:.|.        :|||..|.    |||..||||
  Rat   210 MELLQMGLSRRRSSSHTLNQASSRSHALLTLHISRPTSQQVPPVDLGEPPVG----GKLCFVDLA 270

  Fly   260 GSERQSKTQASGQRLKEATKINLSLSVLGNVISALVD--GKSTHIPYRNSKLTRLLQDSLGGNSK 322
            |||:.:.|.:.||.:.||..||.||..||:.||.|:|  .|.:|||:|:||||:||.|||||...
  Rat   271 GSEKVAATGSRGQLMLEANSINRSLLALGHCISLLLDPQRKQSHIPFRDSKLTKLLADSLGGRGV 335

  Fly   323 TVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPK-------DALLRHFQEEIARLRKQ 380
            |:|.|.:||:.....||:|||||||||:.|..|....:.|.       :|.|...|||...||.|
  Rat   336 TLMVACVSPSAQCLPETLSTLRYASRAQRITTRPQGPKSPAVKPPQQVEAELLQLQEENRCLRLQ 400

  Fly   381 LEEGDSLEEEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNE 445
            |   |.:..:.|                   .:..:.:...::......::...|.|:|.|...:
  Rat   401 L---DQMYTKAP-------------------RVHGARVAWAQRNLYGMLQEFMLENEKLRKEMRQ 443

  Fly   446 HQKEIEHAKTEQETLRNKLVSLEGKILV 473
            .:...:.|:.||..|..::..||.::|:
  Rat   444 LRSSRDLAQAEQHVLAQQIHELERRLLL 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	132/353 (37%)
		Smc	<433..>578	CDD:440809	11/41 (27%)
Kif12	XP_006238315.1	KISc	25..363	CDD:276812	131/351 (37%)