Protein Alignment Klp64D and Kif16b

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_038960967.1
• Gene: Kif16b / 311478
• RGDID: 1310146
• Length: 1876
• Species: Rattus norvegicus
• Alignment Length: 790
• Identity: 243/790 - (30%)
• Similarity: 343/790 - (43%)
• Gaps: 215/790 - (27%)

  Fly    29 PMDKNELSAGALSAISVDKINRAITVMK-PNA----TANEPPKTYYFDNVFDGGSNQMDLYVD-- 86
            ||.|.|....|...|.::|....||.:| |..    :..|..||:.:|..|.....:...||.
  Rat    15 PMSKQEKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFYSADTKSPDYVSQE 79

  Fly    87 -----TARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNP-DSPQTKGIIPNAFAHIFGHIAKAK 145
                 ....:|....||||..:.||||||:||:|||.||. ||    |:||.....:|..|.:..
  Rat    80 TVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS----GLIPRICEALFSRINETT 140

  Fly   146 --ENQKFLVRVSYMEIYNEEVRDLLGKDVGK--SLEVKERPDIGVFVKDLSGYVVHNADDLENIM 206
              :...|...|||:|||||.|||||.:...|  :|.|:|.|..|.:|:|||.::|.|..|:|.:|
  Rat   141 RWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPKEGPYVEDLSKHLVQNYSDVEELM 205

  Fly   207 RLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASG 271
            ..||.||...||.||..||||||||:|...:::. :.::....:.|:.|||||||||...|.|:|
  Rat   206 DAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKF-DAEMPCETVSKIHLVDLAGSERADATGATG 269

  Fly   272 QRLKEATKINLSLSVLGNVISALVD-----------GKSTHIPYRNSKLTRLLQDSLGGNSKTVM 325
            .||||...||.||..||||||||.|           .|...:|||:|.||.||:|||||||||:|
  Rat   270 VRLKEGGNINKSLVTLGNVISALADLSQDAANPLVKKKQVFVPYRDSVLTWLLKDSLGGNSKTIM 334

  Fly   326 CATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGD--SLE 388
            .|||||||.||.||:||||||:|||||.|:..|||:....|:|..:.|||||:..|.:|:  :|.
  Rat   335 IATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALL 399

  Fly   389 EEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKTD--AEKEELAKRKN------- 444
            :.|.:...||....:|           :.:|.:.|:...|..:|.  .:::.||.||.
  Rat   400 DSPTALSMEEKLHQNE-----------ARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLD 453

  Fly   445 --------------------EHQKE------IEHAKTEQETLRN------------------KLV 465
                                .|.||      .|.|.|||:.:.:                  .|:
  Rat   454 SELPHLIGIDDDLLSTGIILYHLKEGQTYVGREDASTEQDIVLHGLDLESEHCVFENAGGTVTLI 518

  Fly   466 SLEGK--------------------ILVGGENL-------------------------------- 478
            .|.|.                    ||:|..|:
  Rat   519 PLSGSQCSVNGVQIVDATQLNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLS 583

  Fly   479 ----------------------------LEKAQTQELLLEQS----IAELEQHEKSEEALKQTLQ 511
                                        .|:.|.:||...:|    |.|:|:.:||::|..:.:|
  Rat   584 KSCENLSAVMLYNPGLFPMKGPICLRLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQ 648

  Fly   512 Q------KATERI--DIEERYSTLQDASTGITKKIHRVMQMLMGVKSE-LADQQ--QEHQREKEG 565
            |      |.||.:  .|.::..:|:..|..|..|:..::......:.| |.:||  ::.:|::|.
  Rat   649 QEVETRRKETEIVQRQIRKQEESLKRRSFHIENKLKDLLAEKERFEEERLREQQGLEQQKRQEED 713

  Fly   566 IYENIRSLSRELALCELVLNSYVPKEYQSMIN--QYTHWNEDIGEWQLKC--------------- 613
            .:..||...|.|.    .|||:...|....:.  .:.|..:|....:|:.
  Rat   714 SFFRIREELRRLQ----ELNSHEQAEKGQPLQDLDWLHREQDAQSAKLQLEKRRLEEQEKEQVLR 774

  Fly   614 VAYTGNNMRK 623
            ||:....:||
  Rat   775 VAHLEEQLRK 784

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	158/350 (45%)
		Smc	<433..>578	CDD:440809	49/292 (17%)
Kif16b	XP_038960967.1	KISc_KIF1A_KIF1B	15..368	CDD:276816	161/357 (45%)
		Kinesin_assoc	367..479	CDD:465047	27/122 (22%)
		FHA	449..565	CDD:469597	15/115 (13%)
		Smc	<609..>1087	CDD:440809	42/180 (23%)