Protein Alignment Klp64D and Kif20b

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_006231343.1
• Gene: Kif20b / 309523
• RGDID: 1308497
• Length: 1781
• Species: Rattus norvegicus
• Alignment Length: 784
• Identity: 191/784 - (24%)
• Similarity: 321/784 - (40%)
• Gaps: 213/784 - (27%)

  Fly     6 ANAGTTAQLDDEIEN-VRVVVRTRPMDKNELSAGALSAISV-DKINRAITVMKPNA--------T 60
            ||.|..:.   |.:| ::|.:|.||..::|....|...:.| |  ::.:.:..|.:        :
  Rat    46 ANPGANSL---ESKNYLQVCLRIRPFTQSEKGHEAEGCVQVLD--SQTVLLKDPQSILGHLSEKS 105

  Fly    61 ANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQ 125
            :.:..:.:.|..||...::|.:.:.......|..:|:|::..|..||.|.:|||||..|   :.:
  Rat   106 SGQMAQKFSFSRVFGPETSQKEFFQGCIMQPVKDLLKGHSRLIFTYGLTNSGKTYTFQG---TEE 167

  Fly   126 TKGIIPNAFAHIF---------------------------------------------------- 138
            ..||:|.....:|
  Rat   168 NIGILPRTLNVLFDSLQERLYTKMSFKPHRCREYLQLSSDQEKEESANKNTLLRQIKEVTIHNDS 232

  Fly   139 -----GHIAKA-------------------KENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVK 179
                 |.:..:                   .:|.|:.|.||:.|||||.:.||.   |..|.:::
  Rat   233 YDILCGRLTNSLTIPEFEETMNNCEQSSLNVDNIKYSVWVSFFEIYNESIYDLF---VPVSSKLQ 294

  Fly   180 ERPDIGV--------FVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVE 236
            :|..:.:        |:|||....|.::.:...:::||.|:::|..||:|..|||||:||:|.:.
  Rat   295 KRKMLRLSQDVKGYSFIKDLQWIQVSDSKEAYRLLKLGVKHQSVAFTKLNNASSRSHSIFTIRIL 359

  Fly   237 RSELGEGDVQHV-RMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKST 300
            :.|  :.::..| |:.:|.|.|||||||..|||:.|:||:||..||.||..||..||.|.:...:
  Rat   360 QIE--DSEIPRVTRVSELSLCDLAGSERSMKTQSEGERLREAGNINTSLLTLGKCISVLKNSDKS 422

  Fly   301 ----HIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAK----------- 350
                |:|:|.||||...|....|..|..|...||...|.|.||::.|::::.|:
  Rat   423 KIQQHVPFRESKLTHYFQSFFTGKGKICMIINISQCCSAYDETLNVLKFSTVAQKVYVPDTLSSS 487

  Fly   351 ------------------NIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEE 397
                              |:.|:: :|.:.|.....:..|::......:|:   |||...:...|
  Rat   488 QEKSFGSTKSLQDVSLGSNLDNKI-LNVKRKTVSWENSLEDVVENEDLVED---LEENEETQNME 548

  Fly   398 EDTADDELEAPLEIELESSTIQAVEKKPKK---------------KREKTDAE---KEELAKRKN 444
            .:..|::.:.|    ||...:.|...|.||               |:||...|   :||:.:...
  Rat   549 TELTDEDSDKP----LEEGGVCAGHGKNKKLLDLIENLKKRLINEKKEKLTLEFKIREEVTQEFT 609

  Fly   445 EH--QKEIEHAKTEQETLRNKLVSLEG---------KILVG--GENLLEKAQ---TQELLLEQSI 493
            ::  |:|.:.    :|||.::...||.         |.|||  ||:..|.|.   |.||..|:|
  Rat   610 QYWSQREADF----KETLLHEREILEENAERRLAIFKDLVGKPGESQDEPASRFCTMELETEES- 669

  Fly   494 AELEQHEKSEEALKQTLQQKATE---RIDIEERYSTL----QDASTGITKKIHRVMQMLMGVKSE 551
                .:....|.:..:|:...|:   :.::...|.|.    |:|...:..|.::|...|...|.|
  Rat   670 ----HNYVGVEDIFDSLEDDVTDIKKQAELAHLYITSLVDPQEAIACLQLKYNQVKAELAETKEE 730

  Fly   552 LADQQQE-HQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQ---YTH-----WNED-- 605
            |...|:| ..:|.:.:.:.:::.|:  ....|:.|.....|...|..:   .||     .|||
  Rat   731 LIKAQEELKNKESDSLVQALKTSSK--VDTSLISNKSTGNETTEMPKKSRTQTHSERKRLNEDGL 793

  Fly   606 -IGE 608
             :||
  Rat   794 QLGE 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	115/460 (25%)
		Smc	<433..>578	CDD:440809	40/171 (23%)
Kif20b	XP_006231343.1	KISc_KIF23_like	58..476	CDD:276819	113/427 (26%)
		RBD_KIF20B	599..647	CDD:409644	12/51 (24%)
		SMC_prok_B	675..1490	CDD:274008	28/125 (22%)