Protein Alignment Klp64D and Kif3b

DIOPT Version :9

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001099999.1
• Gene: Kif3b / 296284
• RGDID: 1306815
• Length: 747
• Species: Rattus norvegicus
• Alignment Length: 639
• Identity: 304/639 - (47%)
• Similarity: 424/639 - (66%)
• Gaps: 44/639 - (6%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDL 83
            |:||||||.|||:..|.:|.....:.||.....::|..|..|::|.|||:.||.|:|..:.|.:|
  Rat     8 ESVRVVVRCRPMNGKEKAAAYDKVVDVDVKLGQVSVKNPKGTSHEMPKTFTFDAVYDWNAKQFEL 72

  Fly    84 YVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQ 148
            |.:|.||:||.||:|:||||.|||||||||||||.|....|:.:|:|||:|.|||.||::: :||
  Rat    73 YDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGVRGDPEKRGVIPNSFDHIFTHISRS-QNQ 136

  Fly   149 KFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNR 213
            ::|||.||:|||.||:||||.||..|.||:|||||.||:|||||.:|..:..::|::|.:||:||
  Rat   137 QYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTKSVKEIEHVMNVGNQNR 201

  Fly   214 AVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEAT 278
            :||||.||:.||||||||.||||.||:|.....|:|:|||.||||||||||:||.|.|:||||||
  Rat   202 SVGATNMNEHSSRSHAIFVITVECSEVGLDGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEAT 266

  Fly   279 KINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTL 343
            |||||||.|||||||||||||||||||:||||||||||||||:||||.|.:.||..|..||::||
  Rat   267 KINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTL 331

  Fly   344 RYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEE---------------------GDSL 387
            |||:|||||:|:..:||:|||||||.||||||||:.|||:                     |:..
  Rat   332 RYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEE 396

  Fly   388 EEEPPSSEEEEDTADD---ELEAPLEIE----LESSTIQAVEKKPKKKREKTDAEKEELAKRKNE 445
            |||....|||.|..||   |.:..||||    :|..::.|             .||..|.|.|.:
  Rat   397 EEEGEEGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVA-------------EEKMRLLKEKEK 448

  Fly   446 HQKEIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEEALKQTL 510
            ..:::...|...|.|..|:.::|.|:||||:|:::....|:.:|||...|:.:.::.|..::|.:
  Rat   449 KMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQM 513

  Fly   511 QQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSR 575
            :.:..|.::::|.|::||......|||:.::...|..||:|:.|.|:||.:|::.:.:....|:|
  Rat   514 ESRDEETLELKETYTSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTR 578

  Fly   576 ELALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNN--MRKHISA 627
            ||.|..|::.:::|.|.::.|...:.::::...|:|..:....|.  |::.:||
  Rat   579 ELKLKHLIIENFIPLEEKNKIMNRSFFDDEEDHWKLHPITRLENQQMMKRPVSA 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	209/332 (63%)
		Kinesin	26..352	CDD:278646	203/325 (62%)
		RILP-like	<437..556	CDD:304877	34/118 (29%)
Kif3b	NP_001099999.1	KISc_KIF3	8..340	CDD:276822	209/332 (63%)
		Smc	<352..>614	CDD:224117	83/274 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG4280
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101005
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720