DRSC/TRiP Functional Genomics Resources

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Protein Alignment Klp64D and Kifc1

DIOPT Version :10

Sequence 1:NP_523934.1 Gene:Klp64D / 38611 FlyBaseID:FBgn0004380 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_001005878.1 Gene:Kifc1 / 294286 RGDID:1359118 Length:693 Species:Rattus norvegicus


Alignment Length:373 Identity:142/373 - (38%)
Similarity:198/373 - (53%) Gaps:53/373 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 QLDDEIENVRVVVRTRPMDKNEL--SAGAL---------------SAISVDKINRAITVMKPNAT 60
            ||.:...|:||..|.||:.:.|.  |.|.|               ..:|.....|:.....|.|.
  Rat   323 QLQELKGNIRVFCRVRPVLEGESTPSPGFLVFPPGPAGPSDPPTRLCLSRSDDRRSTLTRAPAAA 387

  Fly    61 ANEPPKTYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNP-DSP 124
            ...   .:.||.||..||.|.:::.:.:. :|...|:||...|.||||||:|||:||.|.| ..|
  Rat   388 TRH---DFSFDRVFPPGSKQEEVFEEISM-LVQSALDGYPVCIFAYGQTGSGKTFTMEGGPRGDP 448

  Fly   125 QTKGIIPNAFAHIFGHIAKAKENQ--KFLVRVSYMEIYNEEVRDLLG----KDVGKSLEVKERPD 183
            |.:|:||.|..|:|. :|:....|  .:....||:|||||.|||||.    |..|...|::.   
  Rat   449 QLEGLIPRAMRHLFS-VAQEMSGQGWTYSFVASYVEIYNETVRDLLATGTRKGQGGDCEIRR--- 509

  Fly   184 IGVFVKDLSGYVVHNA--------DDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSEL 240
            .|...::|:   |.||        .::|.::.|..:||||..|..|:.|||||::|.:.:.    
  Rat   510 AGPGSEELT---VTNARYVPVSCEKEVEALLHLAQQNRAVARTAQNERSSRSHSVFQLQIS---- 567

  Fly   241 GEGDVQHVRMG-KLQLVDLAGSER--QSKTQASGQ--RLKEATKINLSLSVLGNVISALVDGKST 300
            ||...:.::.| .|.|||||||||  ...|...|:  ||:|...||.|||.||.||.|| ..|.:
  Rat   568 GEHAARGLQCGAPLNLVDLAGSERLDPGLTLGPGERDRLRETQAINSSLSTLGLVIMAL-SNKES 631

  Fly   301 HIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASR 348
            |:||||||||.|||:||||::|.:|...|||.:.|..|::::||:||:
  Rat   632 HVPYRNSKLTYLLQNSLGGSAKMLMFVNISPLEENVSESLNSLRFASK 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Klp64DNP_523934.1 KISc_KIF3 19..352 CDD:276822 140/367 (38%)
Smc <433..>578 CDD:440809
Kifc1NP_001005878.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..24
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 48..156
SMC_prok_B <165..327 CDD:274008 2/3 (67%)
KISc_C_terminal 328..685 CDD:276817 140/368 (38%)
Blue background indicates that the domain is not in the aligned region.

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