Protein Alignment Klp64D and klp8

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_594675.1
• Gene: klp8 / 2542849
• PomBaseID: SPAC144.14
• Length: 511
• Species: Schizosaccharomyces pombe
• Alignment Length: 513
• Identity: 163/513 - (31%)
• Similarity: 245/513 - (47%)
• Gaps: 99/513 - (19%)

  Fly    20 NVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKP--------NATANEPPKTYYFDNVFDG 76
            ||||:||.||....|||..|...:|||..|:.:|:..|        :......|:|:.||..|..
pombe     5 NVRVIVRVRPKSLRELSKSAEDLLSVDSHNKTVTITPPKHGLKHSRHKNRVNGPRTFAFDECFAP 69

  Fly    77 G-------SNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAF 134
            .       |.|.|:|..|...:|..:|||:|...:.|||.||||||::.|....|   ||||:..
pombe    70 SAPESKNLSGQEDVYESTGPLLVKSILEGFNSCFITYGQKGTGKTYSVVGLRGQP---GIIPHIS 131

  Fly   135 AHIFGHIAKAKE---NQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFV-KD-LSGY 194
            ..||..|.|.|:   |....|.:|..||..|...|||..:|..|    ..|...||| || |:||
pombe   132 ESIFEEIDKLKKKSPNTTITVSISLAEIIEETPYDLLQPNVNSS----HTPGETVFVQKDSLTGY 192

  Fly   195 VVH--------NADDLENIMRLGNKNRAVGATKMNQESS--RSHAIFSITVERSELGEGDVQH-- 247
            .:|        :|.:::..:||..||.   .|:::..|.  :.|::||:.|:: .:.:...:|
pombe   193 HLHGLSEFEVGSAQEIDAFLRLAAKNI---RTELSDISGVRKGHSVFSLVVQQ-RIIDPKTRHSL 253

  Fly   248 VRMGKLQLVDLA----GSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKS-THIPYRNS 307
            .:..:||::|||    ||:|.....:.     |::..|.|||||..||:||...|: ..|||::|
pombe   254 KKASRLQIIDLASFSKGSQRNESISSF-----ESSSNNKSLSVLNRVIAALTSKKNDVLIPYKDS 313

  Fly   308 KLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHIN------------- 359
            .||.||||:||||.:|:|...:||.|  :.:|.|.|||:..|:.|:|..:||
pombe   314 VLTTLLQDALGGNCRTIMLTCVSPCD--FDDTFSALRYSEAARRIKNISNINCKEAYSTNNEGEL 376

  Fly   360 -------EEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDTADDELEA---------- 407
                   |..::.|.|| :|...:|.|.:||..:..||...:.|.:::|   |:|
pombe   377 DDILTTLESDREQLRRH-EEHSQKLLKFIEEIRNDYEERIHALESQNSA---LKAHLRLAVDAYL 437

  Fly   408 -PLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHAKTEQETLRNKL 464
             |||...:...:     |.|:......|.|:||    |..|.|:.....:.:.::::|
pombe   438 NPLEFNFDDKNV-----KLKEFGSPNIAYKQEL----NSFQGELSSLFKDLKLVKSQL 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	131/368 (36%)
		Smc	<433..>578	CDD:440809	8/32 (25%)
klp8	NP_594675.1	KISc	5..354	CDD:276812	130/366 (36%)