Protein Alignment Klp64D and kif11

DIOPT Version :9

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_775368.2
• Gene: kif11 / 195818
• ZFINID: ZDB-GENE-020426-1
• Length: 1062
• Species: Danio rerio
• Alignment Length: 631
• Identity: 221/631 - (35%)
• Similarity: 331/631 - (52%)
• Gaps: 66/631 - (10%)

  Fly    12 AQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDG 76
            |:.|::..|::||||.||.:..|..:|:.:.:..|:..:.:.:....||.....|||.||.||..
Zfish     9 AKKDEKGRNIQVVVRCRPFNTVERKSGSHTVVECDQNRKEVIMRTGGATDKAARKTYTFDMVFGP 73

  Fly    77 GSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSG--NPDSPQT------KGIIPNA 133
            .:.|:::|.....||:|:|:.|||.||.||||||||||:||.|  :|:...|      .||||..
Zfish    74 SAKQIEVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGDRSPNEEFTWEEDPLAGIIPRT 138

  Fly   134 FAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLL--GKDVGKSLEVKERP--DIGVFVKDLSGY 194
            ...||..:  :....:|.|:||.:||||||:.|||  ..||.:.|::.:.|  ..||.:|.|...
Zfish   139 LHQIFEKL--SNNGTEFSVKVSLLEIYNEELFDLLSPAPDVTERLQLFDDPRNKRGVTIKGLEEI 201

  Fly   195 VVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLA 259
            .|||.:::..|:..|...|...:|.||..|||||::||:|:...|:.....:.|::|||.|||||
Zfish   202 TVHNKNEVYQILERGAAKRKTASTLMNAYSSRSHSVFSVTIHMKEITLDGEELVKIGKLNLVDLA 266

  Fly   260 GSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTV 324
            |||...::.|..:|.:||..||.||..||.||.|||: :..|:|||.|||||:|||||||.:||.
Zfish   267 GSENIGRSGAVDKRAREAGNINQSLLTLGRVIKALVE-RGPHVPYRESKLTRILQDSLGGRTKTS 330

  Fly   325 MCATISPADSNYMETISTLRYASRAKNIQNRMHINEE-PKDALLRHFQEEIARLRKQL-----EE 383
            :.||:|||..|..||:|||.||:|||:|.|:..:|:: .|..|::.:.|||.||::.|     :.
Zfish   331 IIATVSPASINLEETLSTLDYANRAKSIMNKPEVNQKLTKRTLIKEYTEEIERLKRDLAATRDKH 395

  Fly   384 GDSLEEEPPS-------SEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAK 441
            |..|..:...       |:||:.|...|..|.:|.||:.  |..:....|:|.|:...:.::..:
Zfish   396 GVYLSVDNYETLNGKIVSQEEQITEYTERIAAMEEELKK--IIDLFTDSKQKLEQCTEDLQDKNQ 458

  Fly   442 RKNEHQK---EIEHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSE 503
            |..|..|   |..|...::|.:..:|.:.|..:....:.||..|:..    .|.:..|  |.|
Zfish   459 RLEEAHKDLSETRHRLNQEEFISTQLQTNESHLYNTADQLLSTAEAS----TQDVGGL--HAK-- 515

  Fly   504 EALKQTLQQKATERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYE 568
                  ||:|.    |:|...|.:|::.:...:..:..||      :.|.:|.|:|    ..:.:
Zfish   516 ------LQRKK----DVELHNSKVQESFSQCMENCYNSMQ------TSLKEQSQKH----AAMID 560

  Fly   569 NIRSLSRELALCELVLNSYVPKEYQSMI-NQYTHWNEDIGEWQLKC 613
            ..||...||    |..|..|.||..|.: ..|:.....:||...:|
Zfish   561 YYRSSVGEL----LNTNGKVFKETLSAVCESYSSIKGAVGEGVERC 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	151/344 (44%)
		Kinesin	26..352	CDD:278646	147/337 (44%)
		RILP-like	<437..556	CDD:304877	25/121 (21%)
kif11	NP_775368.2	KISc_BimC_Eg5	15..367	CDD:276815	154/354 (44%)
		KISc	17..365	CDD:214526	153/350 (44%)
		Microtub_bind	926..1061	CDD:290642

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4221
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940