Protein Alignment Klp64D and klp-11

DIOPT Version :9

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001369897.1
• Gene: klp-11 / 177685
• WormBaseID: WBGene00002222
• Length: 782
• Species: Caenorhabditis elegans
• Alignment Length: 656
• Identity: 275/656 - (41%)
• Similarity: 391/656 - (59%)
• Gaps: 46/656 - (7%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMDL 83
            |.|:|:||.||:...|: |...|.|...:..|....:|.....:||.|.:.||.::|..|.|.||
 Worm    12 ETVKVIVRCRPLSSQEI-ANNYSKIVHMRPQRGQIELKNPKEQDEPSKDFTFDAIYDENSTQSDL 75

  Fly    84 YVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKENQ 148
            |.:|.|.:||.||.|||.||.||||||||||:||.|....|:.:|:|.....|||.|:| |..||
 Worm    76 YEETFRDLVDSVLNGYNATIFAYGQTGTGKTHTMEGKSSDPEQRGVIYKCIDHIFEHMA-ASHNQ 139

  Fly   149 KFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIMRLGNKNR 213
            ::|||.||:|||.||:||||..:..|.||:|||||.||:||||:..:.....::..:|..||.:|
 Worm   140 EYLVRASYLEIYQEELRDLLEAESNKKLEIKERPDGGVYVKDLTSKLTRTVGEIHEVMIRGNGHR 204

  Fly   214 AVGATKMNQESSRSHAIFSITVERSELGEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEAT 278
            :||.|.||:.||||||||.||||.|.:||....|:.:|:|.|||||||||||||.|:|:|.||||
 Worm   205 SVGRTNMNEHSSRSHAIFIITVECSRIGEDGESHITVGRLNLVDLAGSERQSKTGATGERFKEAT 269

  Fly   279 KINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTL 343
            |||||||.||||||||||.||.|||||:|||||||||||||||||||.|.|.||..|:.||:.||
 Worm   270 KINLSLSALGNVISALVDAKSAHIPYRDSKLTRLLQDSLGGNSKTVMVACIGPASYNFEETLGTL 334

  Fly   344 RYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSS---EEEEDTADDEL 405
            |||:|||||:|:..|||:|||||||.|||||..||:||::..:...:..:.   :.|....:|::
 Worm   335 RYANRAKNIKNQPKINEDPKDALLREFQEEIEMLREQLKQRKTRSRDGATQSFYDAERAKLEDDI 399

  Fly   406 EAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHAKTEQETLRNKLVSLEGK 470
            ||   |:.:.|.|:              .||:.|.:...|....:|..:.||..:..::.:::.:
 Worm   400 EA---IQKDDSLIK--------------HEKDRLIREIQEKHDLLEKERIEQARVAERIANIQSR 447

  Fly   471 ILVGGE---NLLEKAQTQELLLEQSIAELEQHEKSEEALKQTLQQKATERIDIEERYSTLQDAST 532
            ::||.|   .|..:.:.|...||:...||.:.::.|..:.:.|:::..:.:|:::.:|.|:....
 Worm   448 LIVGSEEDGRLESRTKEQHAQLEKKRRELAEQKRREREMVEALERQEEDTVDLKQTFSDLRTEVE 512

  Fly   533 GITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMIN 597
            ..|||:.:::..|...::|:.|....:..|::.:.:.|..:|:||.|..|::.:::|::....|.
 Worm   513 AKTKKLKKMLIKLRQARNEIRDVSGAYSDERQDLDQTIAEVSKELKLKLLIVENFIPRDVSERIK 577

  Fly   598 QYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSAR 662
            :...||||..||.:.....|.:|....::.                .:..|.|||..  ||..|
 Worm   578 ERAEWNEDSFEWNVNAFQSTSSNSSTPLNN----------------TIEVNEDGVFT--RSSGA- 623

  Fly   663 PRTSGV 668
              .|||
 Worm   624 --DSGV 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	192/332 (58%)
		Kinesin	26..352	CDD:278646	188/325 (58%)
		RILP-like	<437..556	CDD:304877	25/121 (21%)
klp-11	NP_001369897.1	Motor_domain	12..343	CDD:419868	192/332 (58%)
		SMC_prok_B	337..>584	CDD:274008	70/263 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145782at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101005
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820