Protein Alignment Klp64D and Kifc3

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001359241.1
• Gene: Kifc3 / 16582
• MGIID: 109202
• Length: 987
• Species: Mus musculus
• Alignment Length: 362
• Identity: 138/362 - (38%)
• Similarity: 209/362 - (57%)
• Gaps: 33/362 - (9%)

  Fly    20 NVRVVVRTRPMDKNELSAG--ALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMD 82
            |:||:.|.||:.|.: ..|  |.:|::.|..:.:|.    :......|.::..|.||...::|.|
Mouse   599 NIRVIARVRPVTKED-GEGPEATNAVTFDPDDDSII----HLLHKGKPVSFELDKVFSPWASQQD 658

  Fly    83 LYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKEN 147
            ::.: .:.::...::|:|..|.||||||.||||||.|.|::|   ||...|...:|..:.:...:
Mouse   659 VFQE-VQALITSCIDGFNVCIFAYGQTGAGKTYTMEGTPENP---GINQRALQLLFSEVQEKASD 719

  Fly   148 QKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIG--VFVKDLSGYVVHNADDLENIMRLGN 210
            .::.:.||..|||||.:||||||:..:.||::..||..  ::|..|:.:.|.:.||:..:...|.
Mouse   720 WQYNITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVDDINKVFEFGY 784

  Fly   211 KNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHVR-MGKLQLVDLAGSERQSKTQASGQRL 274
            .||....|.:|:.||||||:..:||...:...|    :| .|||.|||||||||..|:.|.|.||
Mouse   785 NNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTG----LRTTGKLNLVDLAGSERVGKSGAEGNRL 845

  Fly   275 KEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMET 339
            :||..||.|||.||:||:|| ..:..|:|:||||||.||||||.|:|||:|...:||.:.|..||
Mouse   846 REAQHINRSLSALGDVIAAL-RSRQGHVPFRNSKLTYLLQDSLSGDSKTLMVVQVSPVEKNTSET 909

  Fly   340 ISTLRYASRAKNIQ--------------NRMHINEEP 362
            :.:||:|.|.::::              ::.|:..||
Mouse   910 LYSLRFAERVRSVELGPGSRRTELGSWSSQEHLEWEP 946

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	135/336 (40%)
		Smc	<433..>578	CDD:440809
Kifc3	NP_001359241.1	SMC_N	<230..543	CDD:481474
		KISc_C_terminal	597..924	CDD:276817	135/338 (40%)