Protein Alignment Klp64D and Klp31E

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_061516566.1
• Gene: Klp31E / 1278143
• VectorBaseID: AGAMI1_013230
• Length: 1675
• Species: Anopheles gambiae
• Alignment Length: 833
• Identity: 237/833 - (28%)
• Similarity: 361/833 - (43%)
• Gaps: 233/833 - (27%)

  Fly    15 DDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDGGSN 79
            :|:..:|||.||.||....||       |.:.::...:|..:|...... .|.:.||.|||..:.
Mosquito     4 EDKESSVRVAVRIRPQIPREL-------IDMCRVCTQVTPGEPQVLLGS-DKAFTFDYVFDMSTT 60

  Fly    80 QMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGN-----PDSPQTKGIIPNAFAHIFG 139
            |:.:|.:....:||..|:|||.|:|||||||:||||||...     |::.:  ||||.|..|:|.
Mosquito    61 QVSVYNNCIEKLVDGALQGYNATVLAYGQTGSGKTYTMGTGFERALPEAQE--GIIPRAVRHLFE 123

  Fly   140 HIAKAKENQ-----------KFLVRVSYMEIYNEEVRDLL-----GKDVGKSLEVKERPD----- 183
            .||:.::|.           .|.|...:||:|||||.|||     |..|.|..|     |
Mosquito   124 GIAQLQQNPYDEDGTYLGTVTFSVAAQFMELYNEEVIDLLDPYNKGARVFKIFE-----DATGGI 183

  Fly   184 --IGVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSEL------ 240
              .|..:|.|:|     ..:..|.::.|...|...:|:||::||||||:|:|.:.|..:
Mosquito   184 SVAGATIKPLAG-----PQEALNCLQQGALARTTASTQMNEQSSRSHALFTILIRRQRVMTAEQC 243

  Fly   241 --GEGDVQHVRMGKLQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVD--GKSTH 301
              .|||.:.: ..|...||||||||..:|.|:|:|.:|...||..|..||||||||.|  .|.:|
Mosquito   244 GNAEGDTETL-TSKFHFVDLAGSERLKRTGATGERAREGISINCGLLALGNVISALGDKTKKVSH 307

  Fly   302 IPYRNSKLTRLLQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDAL 366
            :|||:|||||||||||||||:|:|.|.:||:|.::|||::||:||:||:||:|::.||::.....
Mosquito   308 VPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVQINQDQSSRT 372

  Fly   367 LRHFQEEIARLRKQLEE-----------GD------SLEEEPPSSEEE----------------- 397
            :...:.|||.|:.::.|           |:      |||.|..|.:.:
Mosquito   373 ISLLRREIANLQLEILEYKQGKRSIDADGNIAISDVSLENEMLSQDNKRLQQRVKAMQETINALT 437

  Fly   398 -------------------------------------------EDTADDELEAPLEIELESSTIQ 419
                                                       .|:|..||......|:|....:
Mosquito   438 EKNAALQAQQTIASLHKASAAGDGGADATSTNNGSSPVGTAGGNDSAMQELIVGYISEIEKLKAK 502

  Fly   420 AVE--------KKPKKKREK---------TDAEKEELAKRKNEHQKE-----------IEH---- 452
            .:|        ||.|..:.|         .|..:..:...|:|.:||           :||
Mosquito   503 LIESEQMFQQFKKAKSSQSKLGIKTYPFIEDNPETMINMLKHEMEKERETLMSRSLPGLEHESSS 567

  Fly   453 --------AKTEQ----ETLR------NKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQH 499
                    :.||.    |.||      |..:.|:.:::   |.|.|..|..:::       .:|:
Mosquito   568 MDQNSDSDSDTESDDKAEVLRAEMSDVNSDIELKVRLI---EQLEESQQRLQIM-------RQQY 622

  Fly   500 EKSEEALKQTLQQKATERIDIEERYSTLQDASTGITKK----------IHRVMQMLMGVKSELAD 554
            ||....:|:.:.....||   :|..:|:.:..||....          |.||.:......:||..
Mosquito   623 EKQFNLMKEKISNTERER---DEVLATIGNGGTGAMNNKGQNSGNETAIKRVKEDYERKLNELRR 684

  Fly   555 Q-------QQEH---QREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQYTHWNEDIGEW 609
            |       .:||   ||..:.....|::|..|||..:.|....:.|     |.:.::.::::...
Mosquito   685 QLNHFQATNKEHLRLQRNMQAQDAKIKTLRGELAELKQVKTRLMKK-----IQEESNRHKEMESR 744

  Fly   610 QLKCVAYTGNNMRKH---ISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSK 659
            :.:.:|......|||   |.:.:..|...|.:      |...|:.|.|..:|:
Mosquito   745 KTREIAQLRKETRKHKNMIKSLQAQGAAKDQV------LKRKTEEVFNLRKSQ 791

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	151/370 (41%)
		Smc	<433..>578	CDD:440809	41/197 (21%)
Klp31E	XP_061516566.1	None