Protein Alignment Klp64D and LOC1277078

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_061498142.1
• Gene: LOC1277078 / 1277078
• VectorBaseID: AGAMI1_012463
• Length: 2263
• Species: Anopheles gambiae
• Alignment Length: 733
• Identity: 210/733 - (28%)
• Similarity: 306/733 - (41%)
• Gaps: 204/733 - (27%)

  Fly    19 ENVRVVVRTRPMDKNELSAGALSAISV-DKINRAITVMKPNATANEPPKTYYFDNVFDGGSNQMD 82
            :||:|.::.||:.|.|.....:|...: |.|...|       ..|..|  :.||::||.......
Mosquito     3 DNVKVSIKVRPLIKRERENKLVSQWRIRDNIIATI-------DGNGDP--FVFDHIFDETVPTRQ 58

  Fly    83 LYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHIAKAKEN 147
            |:....||::...|.|.||||.|||||.:||||||.||...|   |::|.....||..|.:.||.
Mosquito    59 LFDTVCRPVILSALNGINGTIFAYGQTSSGKTYTMIGNDREP---GVVPLTAREIFEQIKRIKER 120

  Fly   148 QKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERP--DIGVFVKD----LSGYVVHNADDLENIM 206
            | ||:||.::|||||::.||| .....:|::.|..  |:.|..|:    .:..::.:.||
Mosquito   121 Q-FLIRVGFIEIYNEKIHDLL-NTANTNLKIVENQCGDVSVNSKECITNCAEQIIQHVDD----- 178

  Fly   207 RLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEG-------DVQHVRMGKLQLVDLAGSERQ 264
              |||.|.:|.|.||:.|||||.||.||:|...:|..       |.:.|::|.|.|||||||||.
Mosquito   179 --GNKARKIGETNMNERSSRSHTIFRITIESRVIGPANGVDGGMDNEAVQIGILNLVDLAGSERA 241

  Fly   265 SKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTH-IPYRNSKLTRLLQDSLGGNSKTVMCAT 328
            .:|.|:|.|.||...||.||..|..||..|.:..... |.||:|||||:||.|||||:.|.|...
Mosquito   242 DQTGATGSRFKEGVCINKSLLSLSCVIQKLSENSDKQFINYRDSKLTRILQASLGGNAVTSMICN 306

  Fly   329 ISPADSNYMETISTLRYASRAKNIQNRMHINEEPKD-ALLRHFQEEIARLRKQLEEGDSLEEEPP 392
            |:||..:  ||..||.:|.|||||:|:..:||...| |:::..:.||.||:.:|.
Mosquito   307 ITPAVVD--ETYYTLSFAMRAKNIRNKPKVNEILTDAAMMKRLEREIKRLQSELR---------- 359

  Fly   393 SSEEEEDTADDELEAPLEIELESSTI----QAVEKKPKKKREKT--------------------- 432
             ||:.:::....:|....|.|.::..    ||.:......|.:|
Mosquito   360 -SEQNKNSKIKTMELQNAITLRTNQFINSNQAQQSLADNARRRTWCPSTTEIPRLAPGHRPTPDL 423

  Fly   433 -------------------------------------DAEKEELAKRKN---------------- 444
                                                 .|:::.:|.|..
Mosquito   424 MGEGGRTLMGPPPAVTNGGQYLVTMNGATPQIAIRSMSADEDYVATRSGDIRASDGFAATLALIG 488

  Fly   445 ------EHQKEIEH----AKTEQETLRNKLV---SLEGKILVGGENL------------------ 478
                  ::::.::|    |:..:.|..|.|:   |..|...|.||.:
Mosquito   489 EDEPNIQYRELLDHQDLLARRVRSTSPNGLLNPFSSYGDEFVPGEQISFGSASVSPLSTMERELH 553

  Fly   479 -------LEKAQT-----------------QELLLEQSIAELE-----QHEKSE--------EAL 506
                   ..::.|                 ||||..|...:||     ||.|.|        ..|
Mosquito   554 TPKSLRRTRRSSTGDSPPQFNFEQRCRELEQELLELQEFTKLENSVETQHLKKELDKRTGELSEL 618

  Fly   507 KQTLQQKATERIDIEERYSTLQDASTGITKKIHRV-MQMLMGVKSELA--DQQQEHQREKEGI-- 566
            |..|::|......:|||.:.|:....|....:.:. ..:.:.||...|  .:.:.|:.:..||
Mosquito   619 KHDLEKKEQRLEQLEERCAQLEVELKGQMATVSKAENDLALAVKERQAAVREAELHRNQHTGIEF 683

  Fly   567 -YENI--RSLSRELALCE 581
             ||..  ||.:||..|.|
Mosquito   684 EYERYRQRSEAREKELIE 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	141/347 (41%)
		Smc	<433..>578	CDD:440809	46/236 (19%)
LOC1277078	XP_061498142.1	None