Protein Alignment Klp64D and Klp61F

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_061499619.1
• Gene: Klp61F / 1269725
• VectorBaseID: AGAMI1_012015
• Length: 1101
• Species: Anopheles gambiae
• Alignment Length: 651
• Identity: 215/651 - (33%)
• Similarity: 338/651 - (51%)
• Gaps: 99/651 - (15%)

  Fly     5 EANAGTTAQLDDEIENVRVVVRTRPMDKNE---LSAGALSAISVDKINRAITVMKPNATANEPPK 66
            |.|....|......:||:|.||.||.:..|   .|...:..:|..::.     :|.|.|.:...|
Mosquito     9 ERNQSNNAYRPKSNQNVQVYVRVRPTNAREKLIRSQEVVEVVSTRELQ-----LKSNYTDSRTSK 68

  Fly    67 TYYFDNVFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGN---------PD 122
            .:.||..|...|.|.::|.....|.:::||.|:|.|:.||||||||||:||.|.         .|
Mosquito    69 KFTFDRTFAPNSKQHEVYQAVVAPYIEEVLSGFNCTVFAYGQTGTGKTHTMVGEEEQNLSAAWED 133

  Fly   123 SPQTKGIIPNAFAHIFGHIAKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDI--- 184
            ..|| ||||.|..|:|..:...:  .:|.:|:||:|:||||:.|||..|  .:::::...|:
Mosquito   134 DTQT-GIIPRAVNHLFDELRMTE--LEFSMRISYLELYNEELCDLLSTD--DTIKIRIFDDVQKK 193

  Fly   185 -GVFVKDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSELGEGDVQHV 248
             .|.|:.|....||:.||:..::..|.:.|...:|.||.:|||||.||||.|...|.|....:.:
Mosquito   194 GSVIVQGLEEIPVHSKDDVYKLLAKGQERRKTASTLMNAQSSRSHTIFSIIVHIKENGIDGEEML 258

  Fly   249 RMGKLQLVDLAGSERQSKT-QASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRL 312
            ::|||.||||||||..||. ...|.|.:|...||.||..||.||:|||: |:.|||||.||||||
Mosquito   259 KIGKLNLVDLAGSENISKAGNEKGIRTRETVNINQSLLTLGRVITALVE-KTPHIPYRESKLTRL 322

  Fly   313 LQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEE-PKDALLRHFQEEIAR 376
            ||:||||.:||.:.||:||.:.::.||:|||.||.|||||||:...|:: .|..:::.:.|||.|
Mosquito   323 LQESLGGRTKTSIIATVSPGNKDFEETLSTLEYAHRAKNIQNKPEANQKLSKKTVIKEYTEEIDR 387

  Fly   377 LRKQL-----EEGDSLEEEPPS-----SEEEEDTADDELEAPLEIELESSTIQAV---------E 422
            |::.|     :.|..|.||..:     ||......:|:|.....::.:.:..:|:         |
Mosquito   388 LKRDLMAARDKNGIYLAEETYNEMVYKSEAATKELNDKLALIKALKEDLARKEAIFNEVACSLAE 452

  Fly   423 KKPKKKRE-----KTDAE----KEELAKRKNEH-QKEI---EHAKTEQETLRNKLVSLEGKILVG 474
            ::.:.:|.     :|.||    |:.|:|.|..: :|::   .|.||||      :::.:.|.|:
Mosquito   453 REEQLRRTADDLGQTRAELSNTKKNLSKTKRRYVEKKVILEHHLKTEQ------MLTGQAKELI- 510

  Fly   475 GENLLEKAQTQELLLEQSI---AELEQHEKSEEALKQTLQQKATER-ID-IEERYSTLQDASTGI 534
              |::|........|..::   .||:...||           |||: :| :..|..|:||..:.:
Mosquito   511 --NVVESVTEDTNGLHDTVDRRRELDSRNKS-----------ATEQFVDRVRHRIGTIQDDVSKM 562

  Fly   535 TKKIHRV-MQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALCELVLNSYVPKEYQSMINQ 598
            ..:.:|: :.|.:|.:|        :.:::|..|...::   .|:..|.|.:|.: ::..|::..
Mosquito   563 ADECNRLTVDMNVGWES--------YNKQQEAAYIETKA---HLSTLETVSHSLL-QQNASLVGA 615

  Fly   599 Y 599
            :
Mosquito   616 F 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	148/349 (42%)
		Smc	<433..>578	CDD:440809	35/158 (22%)
Klp61F	XP_061499619.1	None