Protein Alignment Klp64D and kif13a

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_073781621.1
• Gene: kif13a / 100331282
• ZFINID: ZDB-GENE-090901-1
• Length: 1937
• Species: Danio rerio
• Alignment Length: 710
• Identity: 234/710 - (32%)
• Similarity: 350/710 - (49%)
• Gaps: 130/710 - (18%)

  Fly    21 VRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKP---NA--TANEPPKTYYFDNVF---DGG 77
            |:|.||.|||::.|:.......:.::. |:  ||:.|   ||  .:.:.||.:.||:.|   |..
Zfish     6 VKVAVRVRPMNRREIELNTKCVVEMED-NQ--TVLHPPPSNAKGESRKQPKVFAFDHCFWSMDES 67

  Fly    78 -----SNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHI 137
                 :.|..::......|:....:|||..|.||||||:||:::|.|:.|.|   |:||.....:
Zfish    68 NIPKYAGQEVVFKCLGEGILQNAFQGYNACIFAYGQTGSGKSFSMMGSGDQP---GLIPRLCCSL 129

  Fly   138 FGHIA-KAKENQKFLVRVSYMEIYNEEVRDLLG-KDVGKSLEVKERPDIGVFVKDLSGYVVHNAD 200
            |..:: :..::..|.|.|||||||||:|||||. |...:||:|:|...:|.:|..||...|.:.:
Zfish   130 FERVSTQQSDSNSFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLGPYVDGLSQLAVTSFE 194

  Fly   201 DLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERS--ELGEGDVQHVRMGKLQLVDLAGSER 263
            |:|::|..|||:|.|.||.||:|||||||:||:.:.::  :|..|: ...::.|:.|||||||||
Zfish   195 DIESLMSEGNKSRTVAATNMNEESSRSHAVFSVILTQTLYDLQSGN-SGEKVSKISLVDLAGSER 258

  Fly   264 QSKTQASGQRLKEATKINLSLSVLGNVISALVD---GKSTH--IPYRNSKLTRLLQDSLGGNSKT 323
            .|||.|:|:||||.:.||.||:.||.|||||.|   |||.:  :|||:|.||.||:|:|||||||
Zfish   259 VSKTGAAGERLKEGSNINKSLTTLGCVISALADQSAGKSRNKFVPYRDSVLTWLLKDNLGGNSKT 323

  Fly   324 VMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLE 388
            .|.||||||..||.||:||||||.|||.|.|...:||:|...::|..:||:.:||:||.:.:|
Zfish   324 AMIATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNARIIRELREEVEKLREQLSQAES-- 386

  Fly   389 EEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKREKTDAEKEELAKRKNEHQKEIEHA 453
                            |:||   ||:    :.:::..|..:|.|...:|:|  ||.|     |.|
Zfish   387 ----------------LKAP---ELQ----EKLQESEKLIQEMTVTWEEKL--RKTE-----EIA 421

  Fly   454 KTEQETLRNKLVSLEGKILVGGE--NLLEKAQTQELLLEQSIAELEQHEKSEEALKQTLQQKATE 516
            :..|:.|.:..:|||...:..||  :.|........|.|..:..|:.|.:......|.:|...
Zfish   422 QERQKQLESMGISLESSGIKVGEDKSFLVNLNADPALNELLVYYLKDHTRVGADTTQDIQLFG-- 484

  Fly   517 RIDIEERYSTLQDASTG------------------ITKKIH-----------------------R 540
             |.|:..:..|:..:.|                  :..|:|                       |
Zfish   485 -IGIQSEHCVLEVTADGDVTLTPAHNARTCVNGMMVYSKVHVWHGDRILWGNNHFFRVNLPNRKR 548

  Fly   541 VMQMLMGVKSEL---ADQQQEHQREKEGIYENIRSLSRELALCELVL-----NSYVPKEYQSMIN 597
            ...:..|...|.   ||.:...:...|..|      |.|.|..|:::     |..:....|::..
Zfish   549 RKDLDRGSPRESFIEADVETASEASSEQDY------SYEFAQMEVMMKALGNNDPMQNAVQALEK 607

  Fly   598 QYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMR 657
            ||........|.|.........::|:.::..:.:         .|..|||||....:.:|
Zfish   608 QYVEEKRLALEEQRLMYERELQSLRQQLTPERNT---------QHQRLSYNTHNTHSRLR 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	161/352 (46%)
		Smc	<433..>578	CDD:440809	36/190 (19%)
kif13a	XP_073781621.1	None