Protein Alignment Klp64D and kif3a

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_017947685.1
• Gene: kif3a / 100145686
• XenbaseID: XB-GENE-986464
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 682
• Identity: 402/682 - (58%)
• Similarity: 507/682 - (74%)
• Gaps: 20/682 - (2%)

  Fly    12 AQLDDEIENVRVVVRTRPMDKNELSAGALSAISVDKINRAITVMKPNATANEPPKTYYFDNVFDG 76
            |...:..:||:||||.||:::.|.:..:..|:.||::...|||.|.: :.||||||:.||.||..
 Frog    73 ADKPESCDNVKVVVRCRPLNERERAMNSKMAVGVDEMRGTITVHKVD-SMNEPPKTFTFDTVFGP 136

  Fly    77 GSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHIFGHI 141
            .|||:|:|..|||||:|.|||||||||.||||||||||:||.|....|:.:|||||:|||:||||
 Frog   137 DSNQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAVPELRGIIPNSFAHVFGHI 201

  Fly   142 AKAKENQKFLVRVSYMEIYNEEVRDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLENIM 206
            |||:.:.:|||||||:||||||||||||||..:.||||||||:||::||||||||:||||::.||
 Frog   202 AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQSQRLEVKERPDVGVYIKDLSGYVVNNADDMDRIM 266

  Fly   207 RLGNKNRAVGATKMNQESSRSHAIFSITVERSELG-EGDVQHVRMGKLQLVDLAGSERQSKTQAS 270
            .||:|||:||||.||:.||||||||:||:|.||.| :|:: |||||||.||||||||||:||.|:
 Frog   267 TLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGADGNI-HVRMGKLHLVDLAGSERQAKTGAT 330

  Fly   271 GQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQDSLGGNSKTVMCATISPADSN 335
            |||||||||||||||.|||||||||||||||:|||||||||||||||||||||:|||.|.|||.|
 Frog   331 GQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYN 395

  Fly   336 YMETISTLRYASRAKNIQNRMHINEEPKDALLRHFQEEIARLRKQLEEGDSLEEEPPSSEEEEDT 400
            |.|||||||||:|||||:|:..|||:|||||||.||:||..|:|:||||:.:.....|..|::|.
 Frog   396 YDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEDLKKKLEEGEDVSGSDDSGTEDDDD 460

  Fly   401 ADDELEAPLEIEL-----------ESSTIQA-VEKKPKKKREKTDAEKEELAKRKNE---HQKEI 450
            .|.|:....|.:.           :.:.:|| ::::.|....|.|.|:||..|.:.|   .:|::
 Frog   461 EDGEIGEDGEKKKKRRGKKKGSPDKMAEMQARIDEERKALEAKLDMEEEERNKARAELERREKDL 525

  Fly   451 EHAKTEQETLRNKLVSLEGKILVGGENLLEKAQTQELLLEQSIAELEQHEKSEEALKQTLQQKAT 515
            ..|:.|..:|..||.:||.|::|||.:||.||:.||.|||:|..|||:..|..|.|::.|::|..
 Frog   526 FKAQQEHHSLLEKLSALEKKVIVGGVDLLAKAEEQERLLEESNFELEERRKRAEKLRRELEEKEQ 590

  Fly   516 ERIDIEERYSTLQDASTGITKKIHRVMQMLMGVKSELADQQQEHQREKEGIYENIRSLSRELALC 580
            ||:||||:|::||:.:.|.|||:.:|..|||..|||:||.|||||||.||:.||||.|||||.|.
 Frog   591 ERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELRLQ 655

  Fly   581 ELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGKEPDFLDLSHVYL 645
            ..:::|::|:|||.||..|.|||||||||||||||||||||||.........|:|..:|||||||
 Frog   656 MNIIDSFIPQEYQEMIENYVHWNEDIGEWQLKCVAYTGNNMRKQTPVPDKKEKDPFEVDLSHVYL 720

  Fly   646 SYNTDGVSNPMRSKSARPRTS-GVPRPTTARR 676
            :|..:.:...: .|..||||| |..||.|.||
 Frog   721 AYTEESLRQSL-MKLERPRTSKGKTRPKTGRR 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	238/333 (71%)
		Smc	<433..>578	CDD:440809	75/147 (51%)
kif3a	XP_017947685.1	KISc_KIF3	80..412	CDD:276822	238/333 (71%)
		Smc	<485..>655	CDD:440809	80/169 (47%)