Protein Alignment Klp64D and kif20bb

DIOPT Version :10

• Sequence 1: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_073774416.1
• Gene: kif20bb / 100007502
• ZFINID: ZDB-GENE-030131-9684
• Length: 1547
• Species: Danio rerio
• Alignment Length: 777
• Identity: 204/777 - (26%)
• Similarity: 331/777 - (42%)
• Gaps: 193/777 - (24%)

  Fly    17 EIENVRVVVRTRPMDKNELSAG-ALSAISVDKINRAI-TVMKPNATANEPPK-------TYYFDN 72
            |.|:::|.:|.||....|.:.| :...||::..:..| ...|.:.||....:       .:.|..
Zfish    40 EKEHLQVYLRVRPFTSTERAEGESQDCISIEPPDTVILKAPKASLTARHSERFGPQLAQRFQFSQ 104

  Fly    73 VFDGGSNQMDLYVDTARPIVDKVLEGYNGTILAYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAHI 137
            |:...:.|.:::..|.:.:|.:||:|.|..|..||.|..|||:|..| |:|  ..||:|.:...|
Zfish   105 VYGPETTQKEIFDGTTKSLVKEVLDGGNSLIFTYGVTNAGKTFTFLG-PES--DGGILPRSLNVI 166

  Fly   138 FGHI-------------------------------------AKAKENQ----------------- 148
            |..|                                     .:.|:|.
Zfish   167 FNSIEGRIYLQNNIKPHRCVDFTRLTKEQQDEEATNKRNLLRRFKDNDSQKTLSSMSSSSCSSFD 231

  Fly   149 --------------------KFLVRVSYMEIYNEEVRDLL-----GKDVGKSLEVKERPDIGVFV 188
                                ||.|.||:.|||||.:.|||     |.....:|.:.:......||
Zfish   232 SSTSSDMNGDSVYLDEDSHVKFSVWVSFCEIYNESIHDLLDFVPNGSHRRNALRLAQDVKSNSFV 296

  Fly   189 KDLSGYVVHNADDLENIMRLGNKNRAVGATKMNQESSRSHAIFSITVERSE-LGEGDVQHVRMGK 252
            |||....|::||:...::::|.||::..:||:|..|||||:||||.:.|.| :|...||.:  .:
Zfish   297 KDLKWVQVNSADEALKVVKIGRKNQSFSSTKLNNISSRSHSIFSIRMLRIEDVGVPRVQTI--SE 359

  Fly   253 LQLVDLAGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKS-----THIPYRNSKLTRL 312
            |.|.|||||||.::||..|:|||||..||.||..||..|:||...::     .|||:|.||||..
Zfish   360 LSLCDLAGSERCARTQNRGERLKEAGNINTSLLTLGKCINALRLNQTQSKFHQHIPFRESKLTHY 424

  Fly   313 LQDSLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDAL-LRHFQEEIAR 376
            ||....|..|..|...|:...|.|.||::.|::::.|:.:   :.:|.:|..:: |:....:::.
Zfish   425 LQGYFCGRGKACMIININQCASVYDETLNVLKFSAVAQKV---VVLNPKPAPSIALKRSARDVSM 486

  Fly   377 LRKQLEEGD------------SLEEEPPSSEEEEDTADDELEAPLEIELESSTIQAVEKKPKKKR 429
            :....::.|            || |:....|.:||..::|:|:..|..::.:.::.||.:
Zfish   487 IINNADKKDWTRRSSIMGWEMSL-EDVQEDENDEDMDEEEVESDDESIVDRTVLETVENQ----- 545

  Fly   430 EKTDAEKEELAKRKNEHQKEIEHAKTEQETLRNKL---VSLEGKILVGGENLLEKAQTQELLLEQ 491
                 |..||..:..|.|:::...::|:.||..::   |:.|...|...   :||..::.|..|:
Zfish   546 -----ELCELQVKIEELQEKLIKEESEKLTLEARIREEVTTEFMELFSN---MEKDYSERLQREK 602

  Fly   492 SIAELEQHEKSEEALK----QTLQQKATERIDIEERYSTLQDA-----STGITK----------- 536
            .|.| |:.|:..|.||    :|:::..|:....:|....|.|.     .:.:||
Zfish   603 EIVE-ERAERRLEILKNLVNRTIEEMTTDENAAKEAKMELLDTMIEAMRSDLTKIKGDAESVQLC 666

  Fly   537 ---------KIHRVMQMLMGVKSE-LADQQQEHQREKE-------------------GIYENIRS 572
                     |:..:...|..:|:| |..|||...:.||                   ..|||.:.
Zfish   667 LANVPESPGKLSHLRTELEEIKAELLKSQQQLSLKSKEFEESCIQMQDLNDQLLQATRNYENQKV 731

  Fly   573 LSREL-ALCELVLNSYVPKEYQSMINQYTHWNEDIGEWQLKCVAYTGNNMRKHISAHKTSGK 633
            ..:|| ::|:         |...|:::.....|...|...|..|.. ||:|:.|...|.|.|
Zfish   732 RCQELMSICQ---------EKDDMVSKLQTALEQNDEAASKDRALI-NNIREEILHFKNSCK 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	130/426 (31%)
		Smc	<433..>578	CDD:440809	44/197 (22%)
kif20bb	XP_073774416.1	None