Protein Alignment lama and Plbd2

DIOPT Version :9

• Sequence 1: NP_001261440.1
• Gene: lama / 38610
• FlyBaseID: FBgn0016031
• Length: 658
• Species: Drosophila melanogaster
• Sequence 2: NP_076114.2
• Gene: Plbd2 / 71772
• MGIID: 1919022
• Length: 594
• Species: Mus musculus
• Alignment Length: 699
• Identity: 173/699 - (24%)
• Similarity: 271/699 - (38%)
• Gaps: 183/699 - (26%)

  Fly    12 TRIGTYILIGA--GLLVIGAFFIGYMERPEYDGTYCATALWTKQVGFQIENWKQQND-------- 66
            |.:.|..|:.:  |||:.|.                |.||.|...|     |::||.
Mouse    24 TSLTTLALLASLTGLLLSGP----------------AGALPTLGPG-----WQRQNPDPPVSRTR 67

  Fly    67 --LVNIPTGVGRI---CYKDSV---------YENGWAQIEVETQRTYPDWVQAYAAGMLEGSLTW 117
              |::..:|..|:   .:.|:|         .|.|||.:::.|...|.|.:||||||::|.|::.
Mouse    68 SLLLDAASGQLRLEDGFHPDAVAWANLTNAIRETGWAYLDLSTNGRYNDSLQAYAAGVVEASVSE 132

  Fly   118 RNIYNQWSNTISSSCERDESTQKFCGWLRDLLTTNYHRLKRQTEKAENDHYWHQLHLFITQLEGL 182
            ..||..|.||:.:.|...|....:|..|::.|..|...::|:.|...:..||||:.|.:.||:||
Mouse   133 ELIYMHWMNTVVNYCGPFEYEVGYCEKLKNFLEANLEWMQREMELNPDSPYWHQVRLTLLQLKGL 197

  Fly   183 ETGYKRGASRARSDLEEEIPFS---------DFLLMNAAADIQDLKIYYENYELQNSTEHTEEPG 238
            |..|           |..:.|.         .|||:..:.|::||:      ...|.|......|
Mouse   198 EDSY-----------EGRLTFPTGRFTIKPLGFLLLQISGDLEDLE------PALNKTNTKPSLG 245

  Fly   239 TDQPKNFFLPSATMLTKIVQEEESPQVLQLLFGHSTAGSYSSMLRIQKRYKFHYHFSSKLRSNTV 303
            :.        |.:.|.|::     |....||..|:|..||.:||||.|:|:..:....:.....|
Mouse   246 SG--------SCSALIKLL-----PGGHDLLVAHNTWNSYQNMLRIIKKYRLQFREGPQEEYPLV 297

  Fly   304 PGVDITFTGYPGILGSTDDFYTIKGRHLHAIVGGVGIKNENLQLWKTVDPKKMVPLVARVMAANR 368
            .|.::.|:.|||.:.|.|||| |.|..|..:...:|  |:|..|||.|.|:..|....|.:.|||
Mouse   298 AGNNLVFSSYPGTIFSGDDFY-ILGSGLVTLETTIG--NKNPALWKYVQPQGCVLEWIRNVVANR 359

  Fly   369 ISQNRQTWASAMSR-HPFTGAKQWITVDLNKMKVQDNLYNVLEGDDKHDDAPVVLNEKDRTAIQQ 432
            ::.:..|||....| :..|...||:.||          |.....:.....:.|:.
Mouse   360 LALDGATWADVFKRFNSGTYNNQWMIVD----------YKAFLPNGPSPGSRVLT---------- 404

  Fly   433 RHDQLRDMVWIAEQLPGMMTKKDVTQGFLVPGNTSWLANGVPYFKNVLELSGV-----------N 486
                      |.||:|||:...|.|....  ..|.|.:..:|||:.|...||:           :
Mouse   405 ----------ILEQIPGMVVVADKTAELY--KTTYWASYNIPYFETVFNASGLQALVAQYGDWFS 457

  Fly   487 YSEDQQLTV--ADEEELTSLASVDKYLRTHGFRGDLLGSQESIAYGNIDLKLFSYNARLGISDFH 549
            |:::.:..:  .|:..:..:.::.:.:|.:.|..|.|...|:     .:.|..:.||....||.:
Mouse   458 YTKNPRAKIFQRDQSLVEDMDAMVRLMRYNDFLHDPLSLCEA-----CNPKPNAENAISARSDLN 517

  Fly   550 AFAGPVFLRFQHTQPRTLEDEGQDGGVPPAASMGDERLSVSIEDADSLAEMELITERRSVRNDMR 614
            ...|....:..|.:..        ||:           .|.:........|.::.
Mouse   518 PANGSYPFQALHQRAH--------GGI-----------DVKVTSFTLAKYMSMLA---------- 553

  Fly   615 AIAMRKIGSG-------PFKWSEMSPVEEGGGHEGHPDEWNFDKVSPKW 656
                   .||       ||:||: ||. ....|.|.||.|.|..:...|
Mouse   554 -------ASGPTWDQCPPFQWSK-SPF-HSMLHMGQPDLWMFSPIRVPW 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lama	NP_001261440.1	Phospholip_B	19..654	CDD:282734	170/688 (25%)
Plbd2	NP_076114.2	Phospholip_B	86..589	CDD:282734	154/610 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I4279
eggNOG	1	0.900	-	-		E1_KOG3774
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4317
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54246
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002308
OrthoInspector	1	1.000	-	-		otm43329
orthoMCL	1	0.900	-	-		OOG6_101392
Panther	1	1.100	-	-	LDO	PTHR12370
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2726
SonicParanoid	1	1.000	-	-		X4061
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860