| Sequence 1: | NP_000517.3 | Gene: | KRT14 / 3861 | HGNCID: | 6416 | Length: | 472 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001260974.1 | Gene: | LamC / 36615 | FlyBaseID: | FBgn0010397 | Length: | 640 | Species: | Drosophila melanogaster |
| Alignment Length: | 415 | Identity: | 127/415 - (30%) |
|---|---|---|---|
| Similarity: | 195/415 - (46%) | Gaps: | 96/415 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 115 EKVTMQNLNDRLASYLDKVRALEEANADLEVKI---RDWYQRQRPAEIKDYSPYFKTIEDLRNKI 176
Human 177 LTATVDNANVLLQIDNARLAAD--------DFRTKYET--ELNLRMSVEA--DING--------- 220
Human 221 ----------------LRRVLDEL-------TLARADLEMQIESLKEELAYLKKNHEEEMNALR- 261
Human 262 ------GQVGGDVNVEMDAAPGVDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEEL----NRE 316
Human 317 V---ATNSELVQSGKSEISELRRTMQNLEIELQSQLSMK-ASLENSLEETKGRYCMQLAQIQEMI 377
Human 378 GSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHL---------------S 427
Human 428 SSQFSSGSQSSRD--VTSSSRQIRT 450 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KRT14 | NP_000517.3 | Head | 1..114 | ||
| Filament | 114..425 | CDD:306535 | 116/371 (31%) | ||
| Coil 1A | 115..150 | 16/37 (43%) | |||
| Linker 1 | 151..168 | 3/16 (19%) | |||
| Coil 1B | 169..260 | 40/134 (30%) | |||
| Linker 12 | 261..283 | 4/28 (14%) | |||
| Coil 2 | 284..422 | 49/145 (34%) | |||
| Tail | 423..472 | 11/45 (24%) | |||
| Interaction with Type I keratins and keratin filaments | 425..472 | 11/43 (26%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 426..472 | 11/42 (26%) | |||
| LamC | NP_001260974.1 | Filament | 45..401 | CDD:278467 | 116/371 (31%) |
| ATP-synt_B | <67..>142 | CDD:304375 | 21/79 (27%) | ||
| MreC | <178..>224 | CDD:302802 | 20/45 (44%) | ||
| LTD | 473..574 | CDD:279300 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||