| Sequence 1: | NP_000517.3 | Gene: | KRT14 / 3861 | HGNCID: | 6416 | Length: | 472 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_508160.1 | Gene: | ifd-2 / 180430 | WormBaseID: | WBGene00002058 | Length: | 443 | Species: | Caenorhabditis elegans |
| Alignment Length: | 377 | Identity: | 74/377 - (19%) |
|---|---|---|---|
| Similarity: | 166/377 - (44%) | Gaps: | 86/377 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Human 115 EKVTMQNLNDRLASYLDKVRALEEANADLE--------------VKIRDWYQRQRPAEIKDYSPY 165
Human 166 FKTIEDLRNKILTATVDNANVLLQIDNARLAAD-DFRTKYET------ELNLRMSVEADINGLR- 222
Human 223 ----------RVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
Human 278 VDLSR-------------------ILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSEL 323
Human 324 VQSGKSEISELRRTMQNLEIELQSQLSMKASLENSL-----------EETKGRYCMQLAQIQEMI 377
Human 378 GSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLSSS 429 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KRT14 | NP_000517.3 | Head | 1..114 | ||
| Filament | 114..425 | CDD:459643 | 72/371 (19%) | ||
| Coil 1A | 115..150 | 18/48 (38%) | |||
| Linker 1 | 151..168 | 1/16 (6%) | |||
| Coil 1B | 169..260 | 16/108 (15%) | |||
| Linker 12 | 261..283 | 4/40 (10%) | |||
| Coil 2 | 284..422 | 32/148 (22%) | |||
| Tail | 423..472 | 2/7 (29%) | |||
| Interaction with Type I keratins and keratin filaments | 425..472 | 2/5 (40%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 426..472 | 1/4 (25%) | |||
| ifd-2 | NP_508160.1 | Filament | 55..402 | CDD:459643 | 72/369 (20%) |
| Blue background indicates that the domain is not in the aligned region. | |||||