DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4669 and CG32436

DIOPT Version :9

Sequence 1:	NP_647956.2	Gene:	CG4669 / 38608	FlyBaseID:	FBgn0035598	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_730622.1	Gene:	CG32436 / 40362	FlyBaseID:	FBgn0052436	Length:	1737	Species:	Drosophila melanogaster

Alignment Length:	566	Identity:	133/566 - (23%)
Similarity:	224/566 - (39%)	Gaps:	112/566 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 AFAHSYYTRRDEWKPDTIDMVVNEGQVLFNDSENMDPPNASDSPDIYDENEQKVTRHFKINDIEF 178
            ||..::....|.|...|:|.::..|..|...|.:::  ..||..| :|..:|...|       :.
  Fly   323 AFVETFRLNPDFWTGSTMDGILKRGVKLTKKSADLN--YKSDVND-FDIIQQVAER-------DA 377

  Fly   179 AMELEAPFEVYGYENVIRNLRRILRAFFKKAKYGVFFTPNWYLLIWKE-KGVWMVLDLNGRDKNT 242
            |:|::..|.  |......|:.:.|..||.|....:|.:.:.:|||||. ...:.:.|.||||:|.
  Fly   378 AVEIKIHFS--GLLKNEPNMYKALSLFFSKYNACIFTSRDLFLLIWKRCLNSYYIFDPNGRDENC 440

  Fly   243 MKPNNEEGYPLLLGLKSFDNVVWLIKKESYLDKNAKFSIREILVV---RLATPGSTGQSWEREHG 304
            .: |.|||...|:..:..:::|.||.|.|.|....:|:|.||.:.   :|..|.......|..|.
  Fly   441 ER-NFEEGKCSLMATRYTEHLVHLITKFSDLQPQDEFNIFEISLTQYGKLKEPPINSAENEEYHK 504

  Fly   305 MRMSQFDVIASDYAYVKSN----------LH--LTLNSKDALRNRSALPVAVATALASKIDHPAT 357
            :           :|.|..|          :|  ::.|.|:|     :|.|::...:.|:.:....
  Fly   505 L-----------WAPVNENFAVKTAATGGIHQPISGNEKNA-----SLVVSLIALIYSEFELAKL 553

  Fly   358 WDQKMYDKVMCYGVNMCKNC----------WEPCMDPSKP-MDLDDFPRQIRLGQFVAEIMLTPN 411
            |.....|.::.|||...|..          |:    ..|| :::.|.|....:|.|.|.:...|.
  Fly   554 WKPGTVDDIIRYGVAYYKTLRKKFRLDGKRWK----NKKPHLNVVDLPEMFLMGAFKATVRKHPF 614

  Fly   412 AYEGWWKCVPMYKFNDFHLMLEKA--LDQNDYIIFQINNQMYSLWKKSDFIYLMDPYRHNIVGRI 474
            ...|.......|..:...:.|.:.  |.|....:.||:|.:.::|:..:|.|:.||:|.|..|.:
  Fly   615 MINGHVADCRNYLESQLTMALHQLFNLPQWPSALLQIDNSVMAVWRDREFFYVFDPFRRNRTGLV 679

  Fly   475 LEEGEDPKS------ATVRMFGNMDRLLSVFHQILLESNRSAVFHIHTLR---IRNITECPPGT- 529
            :    ||..      |.:::....|..:.|.:...|:..|...|.||.:|   ||.:....|.|
  Fly   680 V----DPDDYSIKGLAVLQLHATFDSFVRVIYMNALKMRRGGKFFIHGVRTGCIRPLQVMTPQTN 740

  Fly   530 -APALL---------PPDEDVE----VRSLNENIRF---DEN----------YDKCLQELGEISD 567
             .|.|.         ||..:::    :.|:.|..||   ||.          .:..::||.|...
  Fly   741 RFPGLQMGLPTFTDEPPMPELKQKKSIESIPEEDRFPTVDEKEMVEELINMIINSIIKELPEPQP 805

  Fly   568 FEEDLVSEIEPIVEISSSEEM----VEEEEGGGGGAVEGGEGEEDD 609
            ....|....:.::..|..|.:    :..:.|     .|.|:.||:|
  Fly   806 KRPHLYKPAQKVLLRSDQENLKALRLRIKRG-----YELGQEEEED 846

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG4669	NP_647956.2	None
CG32436	NP_730622.1	Bud13	1072..>1134	CDD:286779
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28NDP
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0010003
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR40552
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910