DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4669 and ms(3)76Cc

DIOPT Version :9

Sequence 1:	NP_647956.2	Gene:	CG4669 / 38608	FlyBaseID:	FBgn0035598	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_649136.1	Gene:	ms(3)76Cc / 40142	FlyBaseID:	FBgn0036895	Length:	1174	Species:	Drosophila melanogaster

Alignment Length:	555	Identity:	231/555 - (41%)
Similarity:	333/555 - (60%)	Gaps:	32/555 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 KGCTRM-RRNDIDR-SLGYPIGVVSGTTVVKSGI---PNQES---VRFASNLKAFAHSYYTRRDE 125
            |.|.:: .|:|::. |||.|:|:|.....|.:..   |.|:.   :.||:.|||||..|.....:
  Fly    58 KFCEKVPNRSDVEADSLGCPVGLVCSNATVNNPCGCSPKQQEANVLNFATYLKAFALIYVLPETD 122

  Fly   126 WKPDTIDMVVNEGQVLFNDSENM----DPPNASD--SPDIYDENEQKVTRHFKINDIEFAMELEA 184
            |..:.|||::.||..||..|.::    |.|:...  .|:||...|:::.|:|.:....|.:.||.
  Fly   123 WTAEKIDMLLEEGTDLFRASSDVNQGHDDPDEHKLLEPEIYTNEEKRIKRNFNLEGHTFTLALEP 187

  Fly   185 PFEVYGYE-------NVIRNLRRILRAFFKKAKYGVFFTPNWYLLIWKEKGVWMVLDLNGRDKNT 242
            .:...|.:       ::|:||..||::|||.::|.:..|...:||||:.:.|:.|||:.||.|:.
  Fly   188 RYLGVGSKPLDQQPPHIIKNLGTILQSFFKSSRYCLLLTRVGHLLIWRRRRVFFVLDVKGRAKDD 252

  Fly   243 MKPNNEEGYPLLLGLKSFDNVVWLIKKESYLDKNAKFSIREILVVRLATPGSTGQSWEREHGMRM 307
            :....:.|..:|:.|||.||||.|....|.:....:|||||::||||.||  .|:.:.|:...|.
  Fly   253 LATVKDNGVAMLVCLKSIDNVVHLASNLSGISPRDEFSIRELVVVRLETP--DGRIYMRDTSHRS 315

  Fly   308 SQFDVIASDYAYVKSNLHLTLNSKDALRNRSALPVAVATALASKIDHPATWDQKMYDKVMCYGVN 372
            .:|.|:...|||:|..|||:||..|.:||||:|.|||.:.|||||||||.||..|.|:::.|||.
  Fly   316 IEFKVVNKSYAYLKGTLHLSLNKDDPVRNRSSLMVAVGSVLASKIDHPANWDTNMLDRLISYGVE 380

  Fly   373 MCKNCWEPCMDPSKPMDLDDFPRQIRLGQFVAEIMLTPNAYEGWWKCVPMYKFNDFHLMLEKALD 437
            :|::||..|:...:|:|||.||.|:|:||||.|:.|.||...|.|:|.......||...:.:||.
  Fly   381 LCRSCWSDCLRDRRPIDLDTFPTQLRMGQFVLELKLIPNVRTGHWRCGVRIIGTDFEAHVSQALK 445

  Fly   438 QNDYIIFQINNQMYSLWKKSDFIYLMDPYRHNIVGRILEE--GEDPKSATVRMFGNMDRLLSVFH 500
            :...::||||||||::|.|..|.||:|||||.|||..:.|  .|..|.||||||.:...:|||||
  Fly   446 ELGNVVFQINNQMYAIWLKDGFYYLVDPYRHTIVGTHVAEDKAEGAKWATVRMFRDQLTMLSVFH 510

  Fly   501 QILLESNRSAVFHIHTLRIRNITECPPGTAPALLP-PD--EDVEVRSLNENIRFDEN--YDKCLQ 560
            |:|.||||.:.:::|.:||||:.|||.|.  |||| ||  :..||:||||.|.|:|.  ...|.:
  Fly   511 QLLKESNRQSAYYVHVVRIRNLAECPEGY--ALLPMPDGKDSCEVKSLNETIFFNEQQCVRVCNK 573

  Fly   561 ELGEISDFEEDLVSEIEPIVEISSSEEMVEEEEGG 595
            .|.||||:|||:||.:....:|...:.:.|::.||
  Fly   574 SLAEISDYEEDVVSLLTDKSDIDHFQVLDEQQNGG 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
CG4669	NP_647956.2	None
ms(3)76Cc	NP_649136.1	AF-4	<631..>1049	CDD:282905
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28NDP
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0010003
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR40552
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840