DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shep and PAB1

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_174676.2	Gene:	PAB1 / 840313	AraportID:	AT1G34140	Length:	407	Species:	Arabidopsis thaliana

Alignment Length:	334	Identity:	85/334 - (25%)
Similarity:	134/334 - (40%)	Gaps:	73/334 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   226 NGT-VQNQN-------QQGGEQLSK--TNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTT 280
            ||| ::||:       .:|....|:  ||:|::.|.:..||.||..:..::|.|.|. .::....
plant    92 NGTLIRNQHIHVCPFVSRGQWDKSRVFTNVYVKNLVETATDADLKRLFGEFGEITSA-VVMKDGE 155

  Fly   281 NKCKGYGFVDFEQPAFAECAVKGLQGKGV--------QAQMAKQQEQD----------------- 320
            .|.:.:|||:||:...|..|::.:.|..|        :||....:.:|
plant   156 GKSRRFGFVNFEKAEAAVTAIEKMNGVVVDEKELHVGRAQRKTNRTEDLKAKFELEKIIRDMKTR 220

  Fly   321 -PTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNG 384
             ..|||:.||......|.||.:.|::|.:.|.:::......||||||....:.|:..:.:...||
plant   221 KGMNLYVKNLDDSVDNTKLEELFSEFGTITSCKVMVHSNGISKGVGFVEFSTSEEASKAMLKMNG 285

  Fly   385 NTIPGAKDPLLVKFADGGPKKK----NLFKTPDPNARAWRDVSAEGIPVAYDPTM--QQNGVSVN 443
            ..: |.| |:.|..|....:.|    ..|..|.|:.......|....|.    ||  ||
plant   286 KMV-GNK-PIYVSLAQCKEQHKLHLQTQFNNPPPSPHQQPIFSQVVAPA----TMLSQQ------ 338

  Fly   444 VGTPIG----VPYSRFSAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYK 504
              ||:.    .|||...:......|...   ||.:|:.|....|.|.|       ||.:|:....
plant   339 --TPLRGYNFQPYSMCGSRMPNSCPPIS---IPNFMVPQPFRPTLYPP-------APLVGLYGSL 391

  Fly   505 PEAVNQVQP 513
            |:.:  :||
plant   392 PQPL--LQP 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	22/77 (29%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	24/77 (31%)
PAB1	NP_174676.2	RRM_SF	<1..23	CDD:302621
		RRM2_I_PABPs	29..105	CDD:240825	5/12 (42%)
		ELAV_HUD_SF	30..296	CDD:273741	54/206 (26%)
		RRM3_I_PABPs	118..197	CDD:240826	23/79 (29%)
		RRM4_I_PABPs	222..299	CDD:240827	24/78 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010