DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shep and Pabpc5

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001103836.1	Gene:	Pabpc5 / 688518	RGDID:	1587661	Length:	382	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	46/174 - (26%)
Similarity:	84/174 - (48%)	Gaps:	21/174 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 QGGEQLSKT---NLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAF 296
            |..:.|.|:   |::|:.|.:...::.|..:.:.:|.|:|.|.:.|  .|..|||.:|.|:..|.
  Rat    95 QPDDHLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCD--DNGSKGYAYVHFDSLAA 157

  Fly   297 AECAVKGLQG-------------KGVQAQMAKQQEQDP---TNLYIANLPPHFKETDLEAMLSKY 345
            |..|:..:.|             |..:.:.|:.:.:|.   ||:::.|......:..|:.:.|:|
  Rat   158 ANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNFGDDIDDEKLKKLFSEY 222

  Fly   346 GQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIPG 389
            |...|.:::||....|||.||.|.|:.|..::.:...:|.:|.|
  Rat   223 GPTESVKVIRDATGKSKGFGFVRYETHEAAQKAVLELHGKSIDG 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	20/85 (24%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	21/68 (31%)
Pabpc5	NP_001103836.1	RRM1_I_PABPs	22..98	CDD:240824	1/2 (50%)
		ELAV_HUD_SF	29..271	CDD:273741	46/174 (26%)
		RRM2_I_PABPs	104..179	CDD:240825	19/76 (25%)
		RRM3_I_PABPs	198..277	CDD:240826	21/69 (30%)
		RRM_SF	301..377	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910