DRSC/TRiP Functional Genomics Resources

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Protein Alignment shep and RBMS2

DIOPT Version :10

Sequence 1:NP_001246636.1 Gene:shep / 38605 FlyBaseID:FBgn0052423 Length:590 Species:Drosophila melanogaster
Sequence 2:XP_006719604.1 Gene:RBMS2 / 5939 HGNCID:9909 Length:477 Species:Homo sapiens


Alignment Length:387 Identity:170/387 - (43%)
Similarity:205/387 - (52%) Gaps:85/387 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 QRVPTAASPSNTNSSSSSNTGSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYI 247
            |..|.:.|.|..||||.||                                  |.:|||||||||
Human    30 QMAPPSPSNSTPNSSSGSN----------------------------------GNDQLSKTNLYI 60

  Fly   248 RGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQ 312
            ||||.||||:|||.:|..||.|:|||||||||||||||||||||:.|:.|:.||..|:..|||||
Human    61 RGLQPGTTDQDLVKLCQPYGKIVSTKAILDKTTNKCKGYGFVDFDSPSAAQKAVTALKASGVQAQ 125

  Fly   313 MAKQQEQDPTNLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQ 377
            ||||||||||||||:|||....|.:||.||..:|||:|||||||....|:|||||||||.||||.
Human   126 MAKQQEQDPTNLYISNLPLSMDEQELEGMLKPFGQVISTRILRDTSGTSRGVGFARMESTEKCEA 190

  Fly   378 IIQMFNGNTI------PGAKDPLLVKFADGGPKKKNLFKTPDPNARAW-RDVSAEGIPVAYDPTM 435
            ||..|||..|      |...||||.|||||||||:........|.||| |:.....:.:.|||| 
Human   191 IITHFNGKYIKTPPGVPAPSDPLLCKFADGGPKKRQNQGKFVQNGRAWPRNADMGVMALTYDPT- 254

  Fly   436 QQNGVSVNVGTPIGVPYSRFSAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSP-------QYMQMA 493
                                :|.|.|.|| |.....|..|:.    |::.||       .|.::.
Human   255 --------------------TALQNGFYP-APYNITPNRMLA----QSALSPYLSSPVSSYQRVT 294

  Fly   494 AAPPLGVTSYKPEAVNQ----VQPRGISMMVSG---DTGVPYGTMMPQLATLQIGNSYISPT 548
            ...||.|.:  |..::.    :||.| |::..|   ...:...:||..| |.|:|:..:|.|
Human   295 QTSPLQVPN--PSWMHHHSYLMQPSG-SVLTPGMDHPISLQPASMMGPL-TQQLGHLSLSST 352

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shepNP_001246636.1 RRM_SF 240..321 CDD:473069 61/80 (76%)
RRM2_MSSP 322..400 CDD:409690 50/83 (60%)
RBMS2XP_006719604.1 RRM1_MSSP2 51..134 CDD:409901 62/82 (76%)
RRM2_MSSP2 135..220 CDD:409904 51/84 (61%)

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