DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shep and rbms1a

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_005155779.1	Gene:	rbms1a / 564994	ZFINID:	ZDB-GENE-030131-4967	Length:	398	Species:	Danio rerio

Alignment Length:	469	Identity:	188/469 - (40%)
Similarity:	232/469 - (49%)	Gaps:	112/469 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 PLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGSQSGTLST 211
            ||..|:|....|   ..|.|..::              .|:.::.|:||:||||
Zfish     9 PLRTPSYRKQPP---VAPPTLPMA--------------PPSPSTNSSTNNSSSS----------- 45

  Fly   212 SLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAIL 276
              |:||                  |.|||||||||||||..||||.|||.:|..||.|:||||||
Zfish    46 --SSTT------------------GWEQLSKTNLYIRGLPPGTTDHDLVKLCQPYGKIVSTKAIL 90

  Fly   277 DKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAM 341
            |||||||||||||||:.|..|:.||..|:..||||||||||||||||||::|||....|.:||.:
Zfish    91 DKTTNKCKGYGFVDFDSPVSAQKAVAALKTNGVQAQMAKQQEQDPTNLYLSNLPVSMDEQELENL 155

  Fly   342 LSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTIP------GAKDPLLVKFAD 400
            |..:|||||||||||....|:|||||||||.|||:.:|..|||..|.      ||.:|||.||||
Zfish   156 LKPFGQVVSTRILRDTNGMSRGVGFARMESTEKCDAVISHFNGKFIKSSSGMLGASEPLLCKFAD 220

  Fly   401 GGPKKKNLFKTPDPNARAW-RD--VSAEGIPVAYDP-TMQQNG-------VSVNVGTPIGVPYSR 454
            ||.||:.......||.|.| ||  |...|:.:.||| |..|||       :...:.|..||  |.
Zfish   221 GGQKKRQSQAKYIPNGRTWTRDAEVRLSGMTLTYDPNTALQNGYYAAPYAMGNRLMTQPGV--SP 283

  Fly   455 FSAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYKPEAVNQVQPRGISMM 519
            :.:| :..|||....|:|            :.|..||    .|..|.|...|....:||..:...
Zfish   284 YISP-ISTYPVQNPSWMP------------HQPYIMQ----HPGAVLSPSMEHPMSLQPSAMLAP 331

  Fly   520 VSGDTG----------VPYGTMMPQLATLQIGNSYISPTYPYYA--PPPTIIPTMPMTDSEQAST 572
            ::...|          :|..|.||        .:||    |:|.  .||.|.|........|..:
Zfish   332 LTQQMGHLSLGGTATFIPANTAMP--------GAYI----PHYTHIQPPAIPPEQESGVQPQDVS 384

  Fly   573 AASPDEAYTQYPHQ 586
            ::.|    :.||.|
Zfish   385 SSDP----SSYPFQ 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	49/69 (71%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	47/83 (57%)
rbms1a	XP_005155779.1	RRM_SF	50..135	CDD:302621	63/84 (75%)
rbms1a	XP_005155779.1	RRM_SF	136..221	CDD:302621	48/84 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7401
eggNOG	1	0.900	-	-		E1_KOG4733
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2939
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm24925
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.920