DRSC/TRiP Functional Genomics Resources

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Protein Alignment shep and PABPC1L2A

DIOPT Version :9

Sequence 1:NP_001246636.1 Gene:shep / 38605 FlyBaseID:FBgn0052423 Length:590 Species:Drosophila melanogaster
Sequence 2:NP_001012995.1 Gene:PABPC1L2A / 340529 HGNCID:27989 Length:200 Species:Homo sapiens


Alignment Length:153 Identity:41/153 - (26%)
Similarity:76/153 - (49%) Gaps:16/153 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   244 NLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGL---- 304
            :||:..|....|:..|....:..|.|:|.:...||.|.:..||.:|:::||..|:.|::.|    
Human     3 SLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRALETLNFDV 67

  Fly   305 -QGKGVQAQMAKQQEQDPT-------NLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNS 361
             :|:.|:...:   ::||:       |::|.||........|..:.|.:|.::|.::..|:: ..
Human    68 IKGRPVRIMWS---QRDPSLRKSGVGNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEK-GP 128

  Fly   362 KGVGFARMESREKCEQIIQMFNG 384
            ||.||...:.:|..|:.|.:.||
Human   129 KGYGFVHFQKQESAERAIDVMNG 151

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
shepNP_001246636.1 RRM1_MSSP 243..313 CDD:240689 21/73 (29%)
RRM2_MSSP 322..400 CDD:240690 18/70 (26%)
PABPC1L2ANP_001012995.1 PABP-1234 2..>196 CDD:130689 41/153 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 170..200
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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