DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shep and rbms2

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_004911950.1	Gene:	rbms2 / 100495159	XenbaseID:	XB-GENE-494623	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	493	Identity:	179/493 - (36%)
Similarity:	217/493 - (44%)	Gaps:	146/493 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 AAYRYTAPLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGS 204
            |::.||....:..|.:...|.|                          ..||||   ||....|.
Frog    12 ASFSYTRSHKKQTYVSAAQHMA--------------------------PPSPSN---SSGGGEGG 47

  Fly   205 QSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTI 269
            ..|                            |||||||||||||||...|||:|||.:|..||.|
Frog    48 GGG----------------------------GGEQLSKTNLYIRGLHPSTTDQDLVKLCQPYGKI 84

  Fly   270 ISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAK------------QQEQDPT 322
            :|||||||||||||||||||||:.|..|:.||..|:..||||||||            |||||||
Frog    85 VSTKAILDKTTNKCKGYGFVDFDSPGAAQKAVTALKASGVQAQMAKVTSNLSTHTLRHQQEQDPT 149

  Fly   323 NLYIANLPPHFKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGNTI 387
            ||||:|||....|.:||::|..:|||:|||||||....|:|||||||||.||||.:|..|||..|
Frog   150 NLYISNLPVSMDEQELESLLKPFGQVISTRILRDASGTSRGVGFARMESTEKCEAVISHFNGKYI 214

  Fly   388 ------PGAKDPLLVKFADGGPKKKNLFKTPDPNARAW-RDVSAEGIPVAYDPTMQ-QNGVSVNV 444
                  |..::|||.||||||.||:........|.|.| |:....|:.:.||||.. |||...
Frog   215 KTPPGVPAPQEPLLCKFADGGQKKRQTQGKYIQNGRGWGREGETGGMTLTYDPTSALQNGFYT-- 277

  Fly   445 GTPIGVPYSRFSAPQ---------------VGGYPVAGSQWIP--GYMM--------TQVDDQTS 484
                 .|||  .||.               |..|.|....|:|  .|:|        ..:|...|
Frog   278 -----APYS--IAPNRVIAQAALSPYLPSPVSSYQVHNPSWMPHQSYLMQPTGTVLTPTMDHAIS 335

  Fly   485 YSPQYMQMAAAPPLGVTSYKPEAVNQVQPRGISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTY 549
            ..|..|.......||..|.                  |.|    |..||..|.:|      .|..
Frog   336 IQPASMMGPLTQQLGHLSL------------------GST----GAYMPAAAAMQ------GPYI 372

  Fly   550 PYYAPPPTIIPTMPMTDS----EQASTAASPDEAYTQY 583
            |.|   |::..|:.:.:|    :|.:..::.:.|...|
Frog   373 PQY---PSVPSTVSIEESSGQPQQVAVESTTEHATYSY 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	48/69 (70%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	47/83 (57%)
rbms2	XP_004911950.1	RRM_SF	54..148	CDD:388407	60/93 (65%)
rbms2	XP_004911950.1	RRM2_MSSP2	149..234	CDD:240918	48/84 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7482
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3074
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm49125
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050