DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shep and rbms3

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_004915433.2	Gene:	rbms3 / 100488273	XenbaseID:	XB-GENE-493365	Length:	418	Species:	Xenopus tropicalis

Alignment Length:	473	Identity:	183/473 - (38%)
Similarity:	226/473 - (47%)	Gaps:	112/473 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 QQAAYRYTAPLPQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNT 202
            ||..|        |.|..|.||...|..    |:...|         .|.|....:||||::|
Frog     7 QQPMY--------PQYTYYYPHYLQTKQ----SYAPAP---------HPMAPPSPSTNSSNNS-- 48

  Fly   203 GSQSGTLSTSLSNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYG 267
                       ||:.                   ||||||||||||||...|||:||:.:|..||
Frog    49 -----------SNSI-------------------GEQLSKTNLYIRGLPPCTTDQDLIKLCQPYG 83

  Fly   268 TIISTKAILDKTTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPH 332
            .|:||||||||.||:|||||||||:.||.|:.||..|:..|||||||||||||||||||:|||..
Frog    84 KIVSTKAILDKNTNQCKGYGFVDFDTPAAAQKAVSSLKASGVQAQMAKQQEQDPTNLYISNLPIS 148

  Fly   333 FKETDLEAMLSKYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGN------TIPGAK 391
            ..|.:||.||..:|.|:|||||||....|:|||||||||.||||.:||.|||.      .:|...
Frog   149 MDEQELENMLKPFGHVISTRILRDASGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGVPAPS 213

  Fly   392 DPLLVKFADGGPKKKNLFKTPDPNARAWRDVSAEGIPVAYDP-TMQQNGVSVNVGTPIGVPYSRF 455
            :|||.||||||.||:........|.|.|......|:.:.||| ...|||.              :
Frog   214 EPLLCKFADGGQKKRQNPSKYTQNGRPWPREGDAGMALTYDPAAAMQNGF--------------Y 264

  Fly   456 SAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGV-----TSYKPEAVNQVQPRG 515
            |:|    |.:|.::.||         |||.:|    ..||.|:..     ||:.|.....:||.|
Frog   265 SSP----YNIATNRMIP---------QTSITP----FIAASPVSTYQVQSTSWMPHPPYVMQPTG 312

  Fly   516 ISMMVSGDTGV---PYGTMMP---QLATLQIG--NSYISPT-------YPYYAP-PPTIIPTMPM 564
            ..:..:.|..:   |...|.|   |:..|.:|  .:|::..       .|.|.| |||.:....:
Frog   313 AVITPAMDHTMSIQPANMMGPLTQQMNHLSLGTTGTYMTAAAPMQGTFIPQYTPVPPTAVQVEGV 377

  Fly   565 TDSEQASTAASPDEAYTQ 582
            .......|..|..||..|
Frog   378 VADNSPQTVPSSQEASGQ 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	46/69 (67%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	47/83 (57%)
rbms3	XP_004915433.2	RRM_SF	54..137	CDD:418427	59/82 (72%)
rbms3	XP_004915433.2	RRM2_RBMS3	137..224	CDD:240919	50/86 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7482
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3074
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm49125
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.050