DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment shep and LOC100333618

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_017213345.1	Gene:	LOC100333618 / 100333618	-ID:	-	Length:	401	Species:	Danio rerio

Alignment Length:	469	Identity:	190/469 - (40%)
Similarity:	234/469 - (49%)	Gaps:	107/469 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 PQPAYAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVPTAASPSNTNSSSSSNTGSQSGTLSTSL 213
            ||..| .|.|:....|.....|....|          |:..:.|:||.||||:        ||:
Zfish    10 PQYTY-YYPPYLQAKPPVGPASHPMAP----------PSPGTNSSTNHSSSSS--------STA- 54

  Fly   214 SNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDK 278
                                  |.|||||||||||||...|||.|||.:|..||.|:||||||||
Zfish    55 ----------------------GWEQLSKTNLYIRGLLPSTTDHDLVKLCQPYGKIVSTKAILDK 97

  Fly   279 TTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLS 343
            |||||||||||||:.||.|:.||..|:..|||||||||||||||||||:|||....|.:|||||.
Zfish    98 TTNKCKGYGFVDFDSPAAAQKAVSALKTSGVQAQMAKQQEQDPTNLYISNLPLTMDEQELEAMLK 162

  Fly   344 KYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNGN------TIPGAKDPLLVKFADGG 402
            .:|||||||||||....|:|||||||||.||||.:|..|||.      .:....:|||.||||||
Zfish   163 PFGQVVSTRILRDTNGASRGVGFARMESTEKCEAVISHFNGKFLKTPAGVMAPSEPLLCKFADGG 227

  Fly   403 PKKKNLFKTPDPNARAW-RDVSAE--GIPVAYDPTMQQNGVSVNVGTPIGVPYSRFSAPQVGGYP 464
            .||:........|.|.| ||..:.  |:.:.||||.                    :|.|.|.||
Zfish   228 QKKRQSQNKYVQNGRGWGRDGESRLAGMTLTYDPTT--------------------AAMQNGFYP 272

  Fly   465 VAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYK---PEAVNQ---VQPRG--ISMMVS 521
            .|.|  |...|:||.......||            |::|:   |..|:|   ||..|  ||..:.
Zfish   273 TAYS--ITNRMITQTPMSPYISP------------VSTYQVQNPSWVHQPYIVQHPGAVISPSID 323

  Fly   522 GDTGVPYGTMM----PQLATLQIGNS-YISPTYPY----YAPPPTIIPTMPMT---DSEQASTAA 574
            ....:...:||    .|::||.:.:: ...|..|.    |.||.|.:.|..::   :|.||...:
Zfish   324 HSMSLQQASMMSPLTQQMSTLSLSSAGTFMPASPALQGPYIPPYTHMQTAAVSVEENSPQAQVES 388

  Fly   575 SPDEAYTQYPHQAA 588
            |.|  ::.|.:|.|
Zfish   389 SSD--HSPYTYQQA 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	49/69 (71%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	48/83 (58%)
LOC100333618	XP_017213345.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I7401
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm24925
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.010