DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment shep and rbms1

DIOPT Version :9

Sequence 1:	NP_001246636.1	Gene:	shep / 38605	FlyBaseID:	FBgn0052423	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_012825364.1	Gene:	rbms1 / 100036596	XenbaseID:	XB-GENE-1011124	Length:	408	Species:	Xenopus tropicalis

Alignment Length:	466	Identity:	186/466 - (39%)
Similarity:	233/466 - (50%)	Gaps:	99/466 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 YAAYTPHTATTPATTTVSFLSQPVDYYWYGQRVP----TAASPSNTNSSSSSNTGSQSGTLSTSL 213
            :|.:.|:..:..||.     .||:        ||    ...|||.|.|:::|::.|.|
Frog     7 HAGFGPYYRSLNATR-----KQPI--------VPAHPMAPPSPSTTGSNNNSSSSSSS------- 51

  Fly   214 SNTTNTNTNMGPNGTVQNQNQQGGEQLSKTNLYIRGLQQGTTDKDLVNMCAQYGTIISTKAILDK 278
                                 .|.:||||||||||||...|||:|||.:|..||.|:||||||||
Frog    52 ---------------------SGWDQLSKTNLYIRGLSPNTTDQDLVKLCQPYGKIVSTKAILDK 95

  Fly   279 TTNKCKGYGFVDFEQPAFAECAVKGLQGKGVQAQMAKQQEQDPTNLYIANLPPHFKETDLEAMLS 343
            |||||||||||||:.||.|:.||..|:..|||||||||||||||||||:|||....|.:||:||.
Frog    96 TTNKCKGYGFVDFDSPAAAQKAVSALKASGVQAQMAKQQEQDPTNLYISNLPLSMDEQELESMLK 160

  Fly   344 KYGQVVSTRILRDQQMNSKGVGFARMESREKCEQIIQMFNG---NTIPGAK---DPLLVKFADGG 402
            .:|||:|||||||....|:|||||||||.||||.:|..|||   .|:||..   :|||.||||||
Frog   161 PFGQVISTRILRDSSGTSRGVGFARMESTEKCEAVISHFNGKFIKTLPGVSAPAEPLLCKFADGG 225

  Fly   403 PKKKNLFKTPDPNARAW---RDVSAEGIPVAYDPTMQ--QNG-VSVNVGTPIGVPYSR------- 454
            .||:........|.|||   .:|...|:.:.||||..  ||| |.....||..:..:|
Frog   226 QKKRQNQNKYVQNGRAWPREGEVRLAGMTLTYDPTTAAIQNGYVRRFYPTPYSIATNRMITQTSI 290

  Fly   455 --FSAPQVGGYPVAGSQWIPGYMMTQVDDQTSYSPQYMQMAAAPPLGVTSYKPEAVNQVQPRG-- 515
              :.|..|..|.|....|||.            .|..||.|.|    |.:...|....:||..
Frog   291 TPYIASPVSTYQVQSPSWIPP------------QPYIMQHAGA----VLTPSMEHTMSLQPASMM 339

  Fly   516 --ISMMVSGDTGVPYGTMMPQLATLQIGNSYISPTYPYYAPPPTIIPTMPMTDSE---QASTAAS 575
              ::..:|..:....||.||  ||..:..:||    |.|    |.:.|..::..|   |...|..
Frog   340 SPLTQQMSHLSLSSSGTYMP--ATTAMQGAYI----PQY----THVQTAAVSVEEPSGQQQVAVE 394

  Fly   576 PDEAYTQYPHQ 586
            ....::.|.:|
Frog   395 TSSEHSPYTYQ 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
shep	NP_001246636.1	RRM1_MSSP	243..313	CDD:240689	49/69 (71%)
shep	NP_001246636.1	RRM2_MSSP	322..400	CDD:240690	49/83 (59%)
rbms1	XP_012825364.1	RRM1_MSSP1	53..138	CDD:240914	62/84 (74%)
rbms1	XP_012825364.1	RRM2_MSSP2	139..224	CDD:240918	50/84 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7482
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	256	1.000	Inparanoid score	I3074
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001320
OrthoInspector	1	1.000	-	-		otm49125
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X530
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.150