Protein Alignment CG4603 and OTU1

DIOPT Version :9

• Sequence 1: NP_001261435.1
• Gene: CG4603 / 38603
• FlyBaseID: FBgn0035593
• Length: 371
• Species: Drosophila melanogaster
• Sequence 2: NP_116610.1
• Gene: OTU1 / 850500
• SGDID: S000001850
• Length: 301
• Species: Saccharomyces cerevisiae
• Alignment Length: 357
• Identity: 109/357 - (30%)
• Similarity: 164/357 - (45%)
• Gaps: 73/357 - (20%)

  Fly     1 MTGSFSVKLKSKKGQFIVNDLNEHTTLGELKTKIVQATDIEATQLHVLVGYPPKPLDLSQQQE-- 63
            :||:...::.:.|....:|||.||..: ::||              :..||||:.::|..:..
Yeast     5 VTGAGINQVVTLKQDATLNDLIEHINV-DVKT--------------MRFGYPPQRINLQGEDASL 54

  Fly    64 -QRALKAVGINSGETLIVE-----EKAAPAPAAPVPGGTTVEDDEALARRLQAEEEAQLLQETAG 122
             |..|..:||||||.:.:|     |..:..|..|.|            :|:....|..:     |
Yeast    55 GQTQLDELGINSGEKITIESSDSNESFSLPPPQPKP------------KRVLKSTEMSI-----G 102

  Fly   123 GPVAQAADYQLPVAPTESGPNGDFNGILLKKVVPADNSCLFTSIRFVLNGKVDNEGSEMMRHIIA 187
            |                ||.|     :|....|..||||||.:|.:   |....:....:|.:::
Yeast   103 G----------------SGEN-----VLSVHPVLDDNSCLFHAIAY---GIFKQDSVRDLREMVS 143

  Fly   188 QEVAADPQSYNDAVLGKSNAEYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGED 252
            :||..:|..:|||:|.|.|.:|..||.|.:|||||||:.|:|:...:.|.||||....|.:|.||
Yeast   144 KEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNED 208

  Fly   253 KNFGLRVFLLFDGIHYDPLYMETSPSAAPATIF---PVEELGVYQQAEQLANEAQSSRQYTNVDK 314
            | |...:.:||:|||||.|.|...     .|:|   ..|...|...|.|||:..:.:....|..|
Yeast   209 K-FDNYILILFNGIHYDSLTMNEF-----KTVFNKNQPESDDVLTAALQLASNLKQTGYSFNTHK 267

  Fly   315 FTLRCMQCDVRLVGQVQAQEHAKQTGHKNFGE 346
            ..::|..|.:..||:.:...||:.|||.:||:
Yeast   268 AQIKCNTCQMTFVGEREVARHAESTGHVDFGQ 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4603	NP_001261435.1	UBQ	5..80	CDD:214563	21/77 (27%)
		UBQ	10..80	CDD:294102	21/72 (29%)
		COG5539	<158..346	CDD:227826	71/190 (37%)
OTU1	NP_116610.1	COG5539	1..300	CDD:227826	109/357 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343619
Domainoid	1	1.000	70	1.000	Domainoid score	I2279
eggNOG	1	0.900	-	-		E1_COG5539
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13176
Inparanoid	1	1.050	136	1.000	Inparanoid score	I1214
Isobase	1	0.950	-	0.811278	Normalized mean entropy	S2422
OMA	1	1.010	-	-		QHG53653
OrthoFinder	1	1.000	-	-		FOG0005589
OrthoInspector	1	1.000	-	-		oto100280
orthoMCL	1	0.900	-	-		OOG6_102949
Panther	1	1.100	-	-	LDO	PTHR13312
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R880
SonicParanoid	1	1.000	-	-		X3996
TreeFam	1	0.960	-	-
	16	15.740