DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4603 and Yod1

DIOPT Version :9

Sequence 1:	NP_001261435.1	Gene:	CG4603 / 38603	FlyBaseID:	FBgn0035593	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001008889.1	Gene:	Yod1 / 363982	RGDID:	1359726	Length:	303	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	148/351 - (42%)
Similarity:	198/351 - (56%)	Gaps:	61/351 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VKLKSKKGQFIVNDLNEHTTLGELKTKIVQATDIEATQLHVLVGYPPKPLDLSQQQEQRALKAVG 71
            ::.|:|.|..::..|:..|.|.||:.:|...|.|......:||||||:.||||.:  ...|..:.
  Rat     4 LRCKAKGGTHVLQGLSNRTRLRELQGQIAAITGIAPGSQRILVGYPPECLDLSDR--DITLGDLP 66

  Fly    72 INSGETLIVEE-----KAAPA---PAAPVPGGTTVEDDEALARRLQAEEEAQLLQETAGGPVAQA 128
            |.||:.|||||     ||:||   ..||                       ..::||
  Rat    67 IQSGDMLIVEEDQTRPKASPAFSKHGAP-----------------------SYVRET-------- 100

  Fly   129 ADYQLPVAPTESGPNGDFNGILLKKVVPADNSCLFTSIRFVLNGKVDNEG-SEMMRHIIAQEVAA 192
                |||              |.:..|||||||||||:.:|:.|.|.|.. :..||.:|||.||:
  Rat   101 ----LPV--------------LTRTAVPADNSCLFTSVYYVVEGGVLNPACAPEMRRLIAQIVAS 147

  Fly   193 DPQSYNDAVLGKSNAEYCAWIQKADSWGGAIEVSILSNYYGIEIDVVDIQNAIINRFGEDKNFGL 257
            ||..|::|:|||:|.|||.||::.|:||||||:||||.:|..||.|||.|...|:|||||..:..
  Rat   148 DPDLYSEAILGKTNEEYCDWIRRDDTWGGAIEISILSKFYQCEICVVDTQTVRIDRFGEDAGYTK 212

  Fly   258 RVFLLFDGIHYDPLYME-TSPSAAPATIFPVEELGVYQQAEQLANEAQSSRQYTNVDKFTLRCMQ 321
            ||.|::||||||||... ..|...|.|||...:..|..||.:||:||:..||:|:|::||||||.
  Rat   213 RVLLIYDGIHYDPLQRNFPDPDTPPLTIFSSNDDIVLVQALELADEARRKRQFTDVNRFTLRCML 277

  Fly   322 CDVRLVGQVQAQEHAKQTGHKNFGEI 347
            |...|.||.:|::||::|||.||||:
  Rat   278 CQKGLTGQAEARDHARETGHTNFGEV 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4603	NP_001261435.1	UBQ	5..80	CDD:214563	26/72 (36%)
		UBQ	10..80	CDD:294102	26/69 (38%)
		COG5539	<158..346	CDD:227826	101/189 (53%)
Yod1	NP_001008889.1	UBQ	<23..70	CDD:294102	18/48 (38%)
		COG5539	32..302	CDD:227826	137/320 (43%)
		OTU	110..225	CDD:303090	66/114 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340494
Domainoid	1	1.000	105	1.000	Domainoid score	I6524
eggNOG	1	0.900	-	-		E1_COG5539
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13176
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3242
OMA	1	1.010	-	-		QHG53653
OrthoDB	1	1.010	-	-		D1327072at2759
OrthoFinder	1	1.000	-	-		FOG0005589
OrthoInspector	1	1.000	-	-		oto98631
orthoMCL	1	0.900	-	-		OOG6_102949
Panther	1	1.100	-	-	LDO	PTHR13312
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3996
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770