DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4603 and otub-3

DIOPT Version :9

Sequence 1:	NP_001261435.1	Gene:	CG4603 / 38603	FlyBaseID:	FBgn0035593	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001255319.1	Gene:	otub-3 / 177679	WormBaseID:	WBGene00009007	Length:	330	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	56/251 - (22%)
Similarity:	84/251 - (33%)	Gaps:	69/251 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 EEKAAPA---------PAAPVPGGT--------------TVEDDEALARRLQAEEE-------AQ 115
            |.:|.||         |.:|.|.|:              ||:.....|::...:::       |:
Worm    94 ESEAVPAENPEASTLSPPSPNPEGSDNDGEGPSSSAFYKTVKISNKAAKKQDKKKKTADKMKAAE 158

  Fly   116 LLQETAGGPVAQAADYQLPVAPTESGPNGDFNGILLKKV-VPADNSCLFTSIRFVLN-------- 171
            ...:.||  ..|.:|.|:..|..:.....|.    :|.: :|||..|::.:|...|.
Worm   159 AADKEAG--KNQLSDRQMEKAAVKEMLAEDH----MKMIDIPADGDCMYNAISHQLQEEGIEISV 217

  Fly   172 -------GKVDNEGSEMMRHIIAQEVAADPQSYNDAVLGKSNAEYCAWIQKADS----WGGAIEV 225
                   |....|.||..|..|......|..|        |.|.|...::....    |||.:|:
Worm   218 RKLRKRCGTYMREHSEDFRPFIEDMANMDSDS--------SWATYLGGVENVAEIGGVWGGELEL 274

  Fly   226 SILSNYYGIEIDVVDIQNAIINRFGED----KNFGLRVFLLFDGIHYDPLYMETSP 277
            ...|..:...| ||..|....:..||:    |:..|||..|.........|..|.|
Worm   275 KACSMIFEKTI-VVYKQYGGRHTIGEEYSSPKDRALRVVFLRHAYSLGEHYNSTCP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4603	NP_001261435.1	UBQ	5..80	CDD:214563
		UBQ	10..80	CDD:294102
		COG5539	<158..346	CDD:227826	34/143 (24%)
otub-3	NP_001255319.1	OTU	194..324	CDD:334900	33/138 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910