DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and OTP43

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_177628.2	Gene:	OTP43 / 843829	AraportID:	AT1G74900	Length:	453	Species:	Arabidopsis thaliana

Alignment Length:	375	Identity:	88/375 - (23%)
Similarity:	154/375 - (41%)	Gaps:	70/375 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SRLVILPATWSCSQNRLLHVRITDQQAGLETKREANRNQNPFREEVFEELITAAPKEHQKFKPEK 96
            :||.:.|..||     |:| |:...:.|...|..|         .|.|...:|.       ||:|
plant   102 ARLHLHPTVWS-----LIH-RMRSLRIGPSPKTFA---------IVAERYASAG-------KPDK 144

  Fly    97 KPK------EKSTKKVQDFGDPDTFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVEYARQIK 155
            ..|      |...  .||....:|..|....:..    ||:...|..:.|....:..|.|...:.
plant   145 AVKLFLNMHEHGC--FQDLASFNTILDVLCKSKR----VEKAYELFRALRGRFSVDTVTYNVILN 203

  Fly   156 DHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGG 220
            ......|..:|:.||::  :.|....|:...||.::.|..:||..|.|:..:.:|::|..::...
plant   204 GWCLIKRTPKALEVLKE--MVERGINPNLTTYNTMLKGFFRAGQIRHAWEFFLEMKKRDCEIDVV 266

  Fly   221 TYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMM 285
            |||::.:..    .|:..:.:|:.:.:.|:.:|..|:|..|||||:...:..:|:.|.::.:||:
plant   267 TYTTVVHGF----GVAGEIKRARNVFDEMIREGVLPSVATYNAMIQVLCKKDNVENAVVMFEEMV 327

  Fly   286 ERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARDC------- 343
            .|..|.|..|:|.|::......|......|:  ..|...|..|::.::|.|:|...:|
plant   328 RRGYEPNVTTYNVLIRGLFHAGEFSRGEELM--QRMENEGCEPNFQTYNMMIRYYSECSEVEKAL 390

  Fly   344 ------GFGD----LDSMREVID-----------KIAPSAARKKPVLQLE 372
                  |.||    ||:...:|.           .:|.:.|..|.:|:|:
plant   391 GLFEKMGSGDCLPNLDTYNILISGMFVRKRSEDMVVAGNQAFAKEILRLQ 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	9/38 (24%)
		PPR_2	182..231	CDD:289786	13/48 (27%)
		PPR	185..215	CDD:279828	9/29 (31%)
		PPR repeat	186..213	CDD:276811	8/26 (31%)
		PPR repeat	219..252	CDD:276811	6/32 (19%)
		PPR_1	252..284	CDD:289614	10/31 (32%)
		PPR_2	256..304	CDD:289786	17/47 (36%)
		PPR repeat	258..287	CDD:276811	10/28 (36%)
		PPR repeat	293..324	CDD:276811	6/30 (20%)
		PPR repeat	330..357	CDD:276811	10/54 (19%)
		PPR repeat	485..514	CDD:276811
		PPR repeat	552..576	CDD:276811
OTP43	NP_177628.2	PPR repeat	60..85	CDD:276811
		PPR repeat	98..120	CDD:276811	8/23 (35%)
		PPR repeat	126..155	CDD:276811	9/44 (20%)
		PPR_2	<136..173	CDD:404055	10/45 (22%)
		PLN03218	<161..>415	CDD:215636	62/265 (23%)
		PPR repeat	163..190	CDD:276811	6/30 (20%)
		PPR repeat	197..224	CDD:276811	5/28 (18%)
		PPR repeat	232..259	CDD:276811	8/26 (31%)
		PPR repeat	265..294	CDD:276811	6/32 (19%)
		PPR repeat	300..329	CDD:276811	10/28 (36%)
		PPR repeat	335..364	CDD:276811	6/30 (20%)
		PPR repeat	370..396	CDD:276811	4/25 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000