DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT1G73710

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_177512.1	Gene:	AT1G73710 / 843706	AraportID:	AT1G73710	Length:	991	Species:	Arabidopsis thaliana

Alignment Length:	625	Identity:	132/625 - (21%)
Similarity:	227/625 - (36%)	Gaps:	153/625 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 EEEEFLSNSTRRSKKLKAVEYARQIKDHL-KANRLNEAIAVL-------EQRM----LKEDRAKP 182
            |:...|...||..:.|:...:.:..:.:: .....|..:..|       |.|:    :..:...|
plant   114 EQTVLLKEQTRWERVLRVFRFFQSHQSYVPNVIHYNIVLRALGRAGKWDELRLCWIEMAHNGVLP 178

  Fly   183 DKYIYNLLISGCAKAGYTRKAFFLYTKMRQR---GLQVTGGTYTSLFNA--------------CA 230
            ....|.:|:....|||..::|......|.||   ..:||..|...:|..              ||
plant   179 TNNTYGMLVDVYGKAGLVKEALLWIKHMGQRMHFPDEVTMATVVRVFKNSGEFDRADRFFKGWCA 243

  Fly   231 -----NAPSVSD----GLAKAQI-LRE------------NMLEKGY-----------EPNV-KNY 261
                 :..|:.|    |.|::.: |::            |.:||..           :|.: ..:
plant   244 GKVDLDLDSIDDFPKNGSAQSPVNLKQFLSMELFKVGARNPIEKSLHFASGSDSSPRKPRLTSTF 308

  Fly   262 NAMIKAYGRCGDVDTAYMLADEMMERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGI 326
            |.:|..||:.|.::.|..|..||::..:.::..|||.::..|.::.......:||  ..|.::||
plant   309 NTLIDLYGKAGRLNDAANLFSEMLKSGVPIDTVTFNTMIHTCGTHGHLSEAESLL--KKMEEKGI 371

  Fly   327 SPDYYSFNAMLRCARDCGFGDLDSMREVIDKIA-----PSAARKKPVLQLEKGQQDDLPSVEANT 386
            |||..::|.:|....|.  ||:::..|...||.     |.....:.||.: ..|:..:..|||..
plant   372 SPDTKTYNILLSLHADA--GDIEAALEYYRKIRKVGLFPDTVTHRAVLHI-LCQRKMVAEVEAVI 433

  Fly   387 TTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLEHMKQHNITPD 451
            ..:...   :....|..:|.::....:.|.:|..:.:   .|||              |.:....
plant   434 AEMDRN---SIRIDEHSVPVIMQMYVNEGLVVQAKAL---FERF--------------QLDCVLS 478

  Fly   452 IETFTAMLEVIPPTNAAEKQLLTFVRKI--------GLKADIDFFNILIKKRSMRFDYESAKEVL 508
            ..|..|:::|.     |||.|......:        |.:.|:..:|::||.......:|.|..:.
plant   479 STTLAAVIDVY-----AEKGLWVEAETVFYGKRNMSGQRNDVLEYNVMIKAYGKAKLHEKALSLF 538

  Fly   509 LMIRTAGLRPDIVTYGVL---ALGCRTQEEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSY 570
            ..::..|..||..||..|   ..|....:||:.:|.:|..:|.|.......||:.        ||
plant   539 KGMKNQGTWPDECTYNSLFQMLAGVDLVDEAQRILAEMLDSGCKPGCKTYAAMIA--------SY 595

  Fly   571 VN--------EIIQLSLEEGLKPNEAFLRHLHNFHRGCARAIDARHPSTKTAAFKKGHSKFCDKY 627
            |.        ::.:...:.|:||||.....|.|   |.|               :.|..:...:|
plant   596 VRLGLLSDAVDLYEAMEKTGVKPNEVVYGSLIN---GFA---------------ESGMVEEAIQY 642

  Fly   628 RLYYEEQGLSG-----LKLEDAIAKV-----KERPYDQFK 657
            ....||.|:..     ..|..|.:||     ..|.||:.|
plant   643 FRMMEEHGVQSNHIVLTSLIKAYSKVGCLEEARRVYDKMK 682

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	7/50 (14%)
		PPR_2	182..231	CDD:289786	16/70 (23%)
		PPR	185..215	CDD:279828	9/32 (28%)
		PPR repeat	186..213	CDD:276811	7/26 (27%)
		PPR repeat	219..252	CDD:276811	10/68 (15%)
		PPR_1	252..284	CDD:289614	9/43 (21%)
		PPR_2	256..304	CDD:289786	13/48 (27%)
		PPR repeat	258..287	CDD:276811	9/29 (31%)
		PPR repeat	293..324	CDD:276811	7/30 (23%)
		PPR repeat	330..357	CDD:276811	6/26 (23%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	5/31 (16%)
AT1G73710	NP_177512.1	PLN03218	<129..>438	CDD:215636	66/313 (21%)
		PPR repeat	147..174	CDD:276811	4/26 (15%)
		PPR repeat	180..209	CDD:276811	7/28 (25%)
		PPR repeat	215..239	CDD:276811	4/23 (17%)
		PLN03077	307..897	CDD:215561	98/432 (23%)
		PPR repeat	307..334	CDD:276811	9/26 (35%)
		PPR repeat	340..369	CDD:276811	7/30 (23%)
		PPR repeat	375..403	CDD:276811	8/29 (28%)
		PPR repeat	410..439	CDD:276811	6/29 (21%)
		PPR repeat	445..470	CDD:276811	4/27 (15%)
		PPR repeat	481..508	CDD:276811	7/31 (23%)
		PPR repeat	514..544	CDD:276811	6/29 (21%)
		PPR repeat	552..579	CDD:276811	8/26 (31%)
		PPR repeat	587..614	CDD:276811	5/34 (15%)
		PPR repeat	620..649	CDD:276811	8/46 (17%)
		PPR repeat	655..684	CDD:276811	8/28 (29%)
		PPR repeat	690..719	CDD:276811
		PPR repeat	724..753	CDD:276811
		PPR repeat	759..786	CDD:276811
		PPR repeat	865..892	CDD:276811
		PPR repeat	898..927	CDD:276811
		PPR repeat	933..959	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050