DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and AT1G63070

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_176495.1	Gene:	AT1G63070 / 842610	AraportID:	AT1G63070	Length:	590	Species:	Arabidopsis thaliana

Alignment Length:	570	Identity:	123/570 - (21%)
Similarity:	224/570 - (39%)	Gaps:	115/570 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 STKKVQDFGDPDT---FGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVEYARQIKD------- 156
            |.|.:||....|.   ||| .|.:...|..||..:.||...:.:|....:....|:::
plant    47 SRKVLQDLKLDDAIGLFGD-MVKSRPFPSIVEFSKLLSAIAKMNKFDLVISLGEQMQNLGISHNL 110

  Fly   157 ---------HLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQ 212
                     ..:.::|:.|:|:| .:|:|.... |.....|.|::|........:|..|..:|.:
plant   111 YTYSIFINYFCRRSQLSLALAIL-GKMMKLGYG-PSIVTLNSLLNGFCHGNRISEAVALVDQMVE 173

  Fly   213 RGLQVTGGTYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTA 277
            .|.|....|:|:|.:........|:.:|    |.|.|:.||.:|::..|.|:|....:.|:.|.|
plant   174 MGYQPDTVTFTTLVHGLFQHNKASEAVA----LVERMVVKGCQPDLVTYGAVINGLCKRGEPDLA 234

  Fly   278 YMLADEMMERQLELNADTFNFLLQACASNSEHGFRH---ALLTWHNMLQRGISPDYYSFNAMLRC 339
            ..|.::|.:.::|.:...:|.::.....     ::|   |...::.|..:||.||.:::|.::.|
plant   235 LNLLNKMEKGKIEADVVIYNTIIDGLCK-----YKHMDDAFDLFNKMETKGIKPDVFTYNPLISC 294

  Fly   340 ARDCGFG-------------------DLDSMREVIDKIAPSAARKKPVLQLEKGQQDDL------ 379
            .  |.:|                   ||.....:||    :..::..:::.|| ..|::
plant   295 L--CNYGRWSDASRLLSDMLEKNINPDLVFFNALID----AFVKEGKLVEAEK-LYDEMVKSKHC 352

  Fly   380 -PSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLE-- 441
             |.|.|..|.:....:.......:|:...:..:..:|:.|....:            :.||.:
plant   353 FPDVVAYNTLIKGFCKYKRVEEGMEVFREMSQRGLVGNTVTYTTL------------IHGFFQAR 405

  Fly   442 ----------HMKQHNITPDIETFTAMLEVIPPTNAAEKQLLTF--VRKIGLKADIDFFNILIKK 494
                      .|....:.|||.|:..:|:.:......|..|:.|  ::|..:|.||..:..:|:.
plant   406 DCDNAQMVFKQMVSDGVHPDIMTYNILLDGLCNNGNVETALVVFEYMQKRDMKLDIVTYTTMIEA 470

  Fly   495 RSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CR--TQEEARELLEQMHVAGIKMNMPILG 556
            .......|...::...:...|::|::|||..:..| ||  .:|||..|..:|...|...|
plant   471 LCKAGKVEDGWDLFCSLSLKGVKPNVVTYTTMMSGFCRKGLKEEADALFVEMKEDGPLPN----- 530

  Fly   557 AMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLRHLHNFHRGCARAIDA 606
                      |.:| |.:|:..|.:|   :||....|....|.|..|.||
plant   531 ----------SGTY-NTLIRARLRDG---DEAASAELIKEMRSCGFAGDA 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	10/38 (26%)
		PPR_2	182..231	CDD:289786	12/48 (25%)
		PPR	185..215	CDD:279828	6/29 (21%)
		PPR repeat	186..213	CDD:276811	6/26 (23%)
		PPR repeat	219..252	CDD:276811	8/32 (25%)
		PPR_1	252..284	CDD:289614	10/31 (32%)
		PPR_2	256..304	CDD:289786	11/47 (23%)
		PPR repeat	258..287	CDD:276811	8/28 (29%)
		PPR repeat	293..324	CDD:276811	4/33 (12%)
		PPR repeat	330..357	CDD:276811	7/45 (16%)
		PPR repeat	485..514	CDD:276811	3/28 (11%)
		PPR repeat	552..576	CDD:276811	3/23 (13%)
AT1G63070	NP_176495.1	PPR_2	73..122	CDD:289786	7/48 (15%)
		PPR repeat	78..104	CDD:276811	4/25 (16%)
		PPR_2	109..157	CDD:289786	10/49 (20%)
		PPR	111..145	CDD:273253	7/35 (20%)
		PPR repeat	112..139	CDD:276811	5/27 (19%)
		PPR_2	143..190	CDD:289786	12/46 (26%)
		PPR_1	143..172	CDD:289614	6/28 (21%)
		PPR repeat	147..174	CDD:276811	6/26 (23%)
		PPR_1	174..207	CDD:289614	9/36 (25%)
		PPR_2	178..227	CDD:289786	14/52 (27%)
		PPR repeat	180..209	CDD:276811	8/32 (25%)
		PPR_1	209..242	CDD:289614	10/32 (31%)
		PPR_2	213..262	CDD:289786	11/48 (23%)
		PPR repeat	217..244	CDD:276811	8/26 (31%)
		PPR_1	246..277	CDD:289614	4/35 (11%)
		PPR_2	249..297	CDD:289786	10/54 (19%)
		PPR repeat	252..279	CDD:276811	4/31 (13%)
		PPR_1	279..311	CDD:289614	8/33 (24%)
		PPR repeat	285..314	CDD:276811	4/30 (13%)
		PPR_1	314..347	CDD:289614	7/37 (19%)
		PPR_2	318..368	CDD:289786	11/54 (20%)
		PPR repeat	320..349	CDD:276811	6/33 (18%)
		PPR_1	350..383	CDD:289614	5/32 (16%)
		PPR_2	354..401	CDD:289786	7/58 (12%)
		PPR repeat	358..385	CDD:276811	3/26 (12%)
		PPR_1	385..418	CDD:289614	4/44 (9%)
		PPR repeat	391..420	CDD:276811	4/40 (10%)
		PPR_1	420..453	CDD:289614	8/32 (25%)
		PPR_2	424..473	CDD:289786	13/48 (27%)
		PPR repeat	428..455	CDD:276811	5/26 (19%)
		PPR_2	460..508	CDD:289786	10/47 (21%)
		PPR repeat	461..490	CDD:276811	3/28 (11%)
		PPR	462..496	CDD:273253	4/33 (12%)
		PPR_1	490..523	CDD:289614	12/32 (38%)
		PPR_2	494..540	CDD:289786	18/61 (30%)
		PPR repeat	496..525	CDD:276811	11/28 (39%)
		PPR repeat	531..559	CDD:276811	9/31 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960