DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and RPF3

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_176481.2	Gene:	RPF3 / 842594	AraportID:	AT1G62930	Length:	629	Species:	Arabidopsis thaliana

Alignment Length:	437	Identity:	105/437 - (24%)
Similarity:	189/437 - (43%)	Gaps:	62/437 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSL 225
            |:.:||:|::::.:.:  ..:||.:.|..:::|..|.|....|..|..||.:..::.....||::
plant   199 NKASEAVALIDRMVAR--GCQPDLFTYGTVVNGLCKRGDIDLALSLLKKMEKGKIEADVVIYTTI 261

  Fly   226 FNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKA---YGRCGDVDTAYMLADEMMER 287
            .:|..|..:|:|.|.    |...|..||..|||..||::|:.   |||..|   |..|..:|:||
plant   262 IDALCNYKNVNDALN----LFTEMDNKGIRPNVVTYNSLIRCLCNYGRWSD---ASRLLSDMIER 319

  Fly   288 QLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLR--CARDCGFGDLDS 350
            ::..|..||:.|:.|..  .|.....|...:..|::|.|.||.:::::::.  |..|    .||.
plant   320 KINPNVVTFSALIDAFV--KEGKLVEAEKLYDEMIKRSIDPDIFTYSSLINGFCMHD----RLDE 378

  Fly   351 MREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLG 415
            .:.:.:            |.:.|   |..|:|....|.:....:.......:||...:..:..:|
plant   379 AKHMFE------------LMISK---DCFPNVVTYNTLIKGFCKAKRVEEGMELFREMSQRGLVG 428

  Fly   416 SLVALEEVTRPHERFLLLGGL---------TGFLEHMKQHNITPDIETFTAMLEVIPPTNAAEKQ 471
            :.|...         .|:.||         ....:.|....:.|||.|::.:|:.:......||.
plant   429 NTVTYN---------TLIQGLFQAGDCDMAQKIFKKMVSDGVPPDIITYSILLDGLCKYGKLEKA 484

  Fly   472 LLTF--VRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CR-- 531
            |:.|  ::|..::.||..:||:|:........|...::...:...|::|:::.|..:..| ||
plant   485 LVVFEYLQKSKMEPDIYTYNIMIEGMCKAGKVEDGWDLFCSLSLKGVKPNVIIYTTMISGFCRKG 549

  Fly   532 TQEEARELLEQMHVAGIKMNM----PILGAMLRQGCANKSFSYVNEI 574
            .:|||..|..:|...|...|.    .::.|.||.|....|...:.|:
plant   550 LKEEADALFREMKEDGTLPNSGTYNTLIRARLRDGDKAASAELIKEM 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	8/34 (24%)
		PPR_2	182..231	CDD:289786	13/48 (27%)
		PPR	185..215	CDD:279828	8/29 (28%)
		PPR repeat	186..213	CDD:276811	8/26 (31%)
		PPR repeat	219..252	CDD:276811	9/32 (28%)
		PPR_1	252..284	CDD:289614	14/34 (41%)
		PPR_2	256..304	CDD:289786	20/50 (40%)
		PPR repeat	258..287	CDD:276811	11/31 (35%)
		PPR repeat	293..324	CDD:276811	7/30 (23%)
		PPR repeat	330..357	CDD:276811	4/28 (14%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	6/27 (22%)
RPF3	NP_176481.2	PPR repeat	54..74	CDD:276811
		PPR_2	78..127	CDD:289786
		PPR repeat	83..109	CDD:276811
		PPR_2	114..162	CDD:289786
		PPR	116..150	CDD:273253
		PPR repeat	117..144	CDD:276811
		PPR_1	145..176	CDD:289614
		PPR_2	148..195	CDD:289786
		PPR repeat	152..179	CDD:276811
		PPR_2	183..232	CDD:289786	8/34 (24%)
		PPR repeat	185..214	CDD:276811	4/14 (29%)
		PPR	186..219	CDD:273253	4/21 (19%)
		PPR_1	214..247	CDD:289614	9/34 (26%)
		PPR repeat	222..249	CDD:276811	8/26 (31%)
		PPR_2	254..302	CDD:289786	17/51 (33%)
		PPR	256..290	CDD:273253	12/37 (32%)
		PPR repeat	257..284	CDD:276811	9/30 (30%)
		PPR_1	284..316	CDD:289614	14/34 (41%)
		PPR repeat	292..319	CDD:276811	10/29 (34%)
		PPR_1	319..351	CDD:289614	8/33 (24%)
		PPR_2	323..371	CDD:289786	12/49 (24%)
		PPR repeat	327..354	CDD:276811	7/28 (25%)
		PPR repeat	360..389	CDD:276811	5/44 (11%)
		PPR	361..395	CDD:273253	8/52 (15%)
		PPR_1	389..422	CDD:289614	7/35 (20%)
		PPR_2	393..440	CDD:289786	8/55 (15%)
		PPR repeat	395..424	CDD:276811	4/28 (14%)
		PPR_2	429..477	CDD:289786	10/56 (18%)
		PPR repeat	430..459	CDD:276811	5/37 (14%)
		PPR	431..461	CDD:279828	5/38 (13%)
		PPR_1	459..489	CDD:289614	8/29 (28%)
		PPR_2	463..512	CDD:289786	15/48 (31%)
		PPR repeat	465..494	CDD:276811	7/28 (25%)
		PPR_2	498..547	CDD:289786	10/48 (21%)
		PPR repeat	500..529	CDD:276811	5/28 (18%)
		PPR	501..535	CDD:273253	6/33 (18%)
		PPR_1	529..562	CDD:289614	10/32 (31%)
		PPR_2	533..579	CDD:289786	12/45 (27%)
		PPR repeat	535..564	CDD:276811	9/28 (32%)
		PPR_2	568..615	CDD:289786	7/29 (24%)
		PPR repeat	570..598	CDD:276811	6/27 (22%)
		PPR repeat	605..629	CDD:276811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960