DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and NG1

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_176459.2	Gene:	NG1 / 842570	AraportID:	AT1G62720	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	384	Identity:	83/384 - (21%)
Similarity:	157/384 - (40%)	Gaps:	66/384 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 IKDHLKANRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVT 218
            |....:.||:.:||.::.:  ::|...:||..|||.:|.|..|.|....|..|:.:|.:.|::..
plant   146 INGFCQGNRVFDAIDLVSK--MEEMGFRPDVVIYNTIIDGSCKIGLVNDAVELFDRMERDGVRAD 208

  Fly   219 GGTYTSLFNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADE 283
            ..||.||......:...||.   |:::|: |:.:...|||..:.|:|..:.:.|....|..|.:|
plant   209 AVTYNSLVAGLCCSGRWSDA---ARLMRD-MVMRDIVPNVITFTAVIDVFVKEGKFSEAMKLYEE 269

  Fly   284 MMERQLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDL 348
            |..|               |                      :.||.:::|:::...  |..|.:
plant   270 MTRR---------------C----------------------VDPDVFTYNSLINGL--CMHGRV 295

  Fly   349 DSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPH 413
            |..::::|            |.:.||   .||.|....|.:....:........:|...:..:..
plant   296 DEAKQMLD------------LMVTKG---CLPDVVTYNTLINGFCKSKRVDEGTKLFREMAQRGL 345

  Fly   414 LGSLVALEEVTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAAEKQLLTF--V 476
            :|..:....:.   :.:...|......|...:.:..|:|.|::.:|..:......||.|:.|  :
plant   346 VGDTITYNTII---QGYFQAGRPDAAQEIFSRMDSRPNIRTYSILLYGLCMNWRVEKALVLFENM 407

  Fly   477 RKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CRTQE 534
            :|..::.||..:||:|.......:.|.|.::...:...||:||:|:|..:..| ||.::
plant   408 QKSEIELDITTYNIVIHGMCKIGNVEDAWDLFRSLSCKGLKPDVVSYTTMISGFCRKRQ 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	12/38 (32%)
		PPR_2	182..231	CDD:289786	17/48 (35%)
		PPR	185..215	CDD:279828	10/29 (34%)
		PPR repeat	186..213	CDD:276811	10/26 (38%)
		PPR repeat	219..252	CDD:276811	9/32 (28%)
		PPR_1	252..284	CDD:289614	8/31 (26%)
		PPR_2	256..304	CDD:289786	11/47 (23%)
		PPR repeat	258..287	CDD:276811	8/28 (29%)
		PPR repeat	293..324	CDD:276811	1/30 (3%)
		PPR repeat	330..357	CDD:276811	4/26 (15%)
		PPR repeat	485..514	CDD:276811	6/28 (21%)
		PPR repeat	552..576	CDD:276811
NG1	NP_176459.2	PPR_2	67..116	CDD:289786
		PPR repeat	71..98	CDD:276811
		PPR_2	103..151	CDD:289786	1/4 (25%)
		PPR	105..139	CDD:273253
		PPR repeat	106..133	CDD:276811
		PPR_1	134..166	CDD:289614	5/21 (24%)
		PPR_2	137..186	CDD:289786	13/41 (32%)
		PPR repeat	141..168	CDD:276811	5/23 (22%)
		PPR_1	168..201	CDD:289614	11/32 (34%)
		PPR_2	172..220	CDD:289786	17/47 (36%)
		PPR repeat	174..203	CDD:276811	10/28 (36%)
		PPR_1	203..236	CDD:289614	9/36 (25%)
		PPR repeat	211..238	CDD:276811	9/30 (30%)
		PPR_1	238..270	CDD:289614	8/31 (26%)
		PPR_2	242..290	CDD:289786	15/86 (17%)
		PPR repeat	246..273	CDD:276811	7/26 (27%)
		PPR_1	273..306	CDD:289614	10/83 (12%)
		PPR_2	277..326	CDD:289786	14/65 (22%)
		PPR repeat	279..308	CDD:276811	6/42 (14%)
		PPR_1	308..340	CDD:289614	7/34 (21%)
		PPR_2	312..359	CDD:289786	5/49 (10%)
		PPR repeat	314..340	CDD:276811	3/25 (12%)
		PPR_1	343..375	CDD:289614	3/34 (9%)
		PPR_2	348..392	CDD:289786	6/46 (13%)
		PPR repeat	349..378	CDD:276811	2/31 (6%)
		PPR	382..416	CDD:273253	7/33 (21%)
		PPR repeat	383..410	CDD:276811	6/26 (23%)
		PPR_2	415..463	CDD:289786	14/47 (30%)
		PPR repeat	416..445	CDD:276811	6/28 (21%)
		PPR	418..451	CDD:273253	8/32 (25%)
		PPR_1	445..478	CDD:289614	9/22 (41%)
		PPR_2	449..>484	CDD:289786	7/18 (39%)
		PPR repeat	451..480	CDD:276811	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960