DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4611 and RPF2

DIOPT Version :9

Sequence 1:NP_647949.1 Gene:CG4611 / 38601 FlyBaseID:FBgn0035591 Length:703 Species:Drosophila melanogaster
Sequence 2:NP_001319294.1 Gene:RPF2 / 842564 AraportID:AT1G62670 Length:630 Species:Arabidopsis thaliana


Alignment Length:465 Identity:105/465 - (22%)
Similarity:188/465 - (40%) Gaps:77/465 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   161 NRLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSL 225
            |:.:||:|::::.:.|  ..:||...|.::::|..|.|.|..||.|..||.|..|:.....|.::
plant   200 NKASEAMALIDRMVAK--GCQPDLVTYGVVVNGLCKRGDTDLAFNLLNKMEQGKLEPGVLIYNTI 262

  Fly   226 FNACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKA---YGRCGDVDTAYMLADEMMER 287
            .:.......:.|.|.    |.:.|..||..|||..|:::|..   |||..|   |..|..:|:||
plant   263 IDGLCKYKHMDDALN----LFKEMETKGIRPNVVTYSSLISCLCNYGRWSD---ASRLLSDMIER 320

  Fly   288 QLELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLR--CARDCGFGDLDS 350
              ::|.|.|.|.....|...|.....|...:..|::|.|.|...::::::.  |..|    .||.
plant   321 --KINPDVFTFSALIDAFVKEGKLVEAEKLYDEMVKRSIDPSIVTYSSLINGFCMHD----RLDE 379

  Fly   351 MREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLG 415
            .:::.:.:.               .:...|.|....|.:....:.......:|:...:..:..:|
plant   380 AKQMFEFMV---------------SKHCFPDVVTYNTLIKGFCKYKRVEEGMEVFREMSQRGLVG 429

  Fly   416 SLVALEEVTRPHERFLLLGGL---------TGFLEHMKQHNITPDIETFTAMLEVIPPTNAAEKQ 471
            :.|...         :|:.||         ....:.|....:.|:|.|:..:|:.:......||.
plant   430 NTVTYN---------ILIQGLFQAGDCDMAQEIFKEMVSDGVPPNIMTYNTLLDGLCKNGKLEKA 485

  Fly   472 LLTF--VRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CR-- 531
            ::.|  :::..::..|..:||:|:........|...::...:...|::||:|.|..:..| ||  
plant   486 MVVFEYLQRSKMEPTIYTYNIMIEGMCKAGKVEDGWDLFCNLSLKGVKPDVVAYNTMISGFCRKG 550

  Fly   532 TQEEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLRHLHNF 596
            ::|||..|.::|...|...|         .||       .|.:|:..|.:|.:...|   .|...
plant   551 SKEEADALFKEMKEDGTLPN---------SGC-------YNTLIRARLRDGDREASA---ELIKE 596

  Fly   597 HRGCARAIDA 606
            .|.|..|.||
plant   597 MRSCGFAGDA 606

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4611NP_647949.1 PPR_2 <157..196 CDD:289786 9/34 (26%)
PPR_2 182..231 CDD:289786 15/48 (31%)
PPR 185..215 CDD:279828 11/29 (38%)
PPR repeat 186..213 CDD:276811 10/26 (38%)
PPR repeat 219..252 CDD:276811 5/32 (16%)
PPR_1 252..284 CDD:289614 13/34 (38%)
PPR_2 256..304 CDD:289786 18/50 (36%)
PPR repeat 258..287 CDD:276811 10/31 (32%)
PPR repeat 293..324 CDD:276811 7/30 (23%)
PPR repeat 330..357 CDD:276811 4/28 (14%)
PPR repeat 485..514 CDD:276811 5/28 (18%)
PPR repeat 552..576 CDD:276811 3/23 (13%)
RPF2NP_001319294.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 104 1.000 Inparanoid score I2129
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.960

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