DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT1G52620

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_175671.1	Gene:	AT1G52620 / 841694	AraportID:	AT1G52620	Length:	819	Species:	Arabidopsis thaliana

Alignment Length:	626	Identity:	132/626 - (21%)
Similarity:	228/626 - (36%)	Gaps:	147/626 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 DTFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVEYARQIKDH-LKAN--RLNEAIAVLEQRM 174
            :|||      |...|..:|.:|:::....|          ::|:. |:.:  .||..|....:..
plant   276 ETFG------TMINGFCKEGDFVASDRLLS----------EVKERGLRVSVWFLNNIIDAKYRHG 324

  Fly   175 LKEDRA-----------KPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNA 228
            .|.|.|           |||...||:||:...|.|....|.....:..::||.....:|..|..|
plant   325 YKVDPAESIGWIIANDCKPDVATYNILINRLCKEGKKEVAVGFLDEASKKGLIPNNLSYAPLIQA 389

  Fly   229 CANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNA 293
            ...:....  :|...:|:  |.|:|.:|::..|..:|......|.:|.|..:..::::|.:..:|
plant   390 YCKSKEYD--IASKLLLQ--MAERGCKPDIVTYGILIHGLVVSGHMDDAVNMKVKLIDRGVSPDA 450

  Fly   294 DTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARDCGF---GDLDSMREVI 355
            ..:|.|:........  |..|.|.:..||.|.|.||.|.:..::.     ||   ||.|..|:|.
plant   451 AIYNMLMSGLCKTGR--FLPAKLLFSEMLDRNILPDAYVYATLID-----GFIRSGDFDEARKVF 508

  Fly   356 DKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVAL 420
            .            |.:|||.:.|:                                .|..:::
plant   509 S------------LSVEKGVKVDV--------------------------------VHHNAMI-- 527

  Fly   421 EEVTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLE--VIPPTNAAEKQLLTFVRKIGLKA 483
                :...|..:|......:..|.:.::.||..|::.:::  |.....|...::..::.|...|.
plant   528 ----KGFCRSGMLDEALACMNRMNEEHLVPDKFTYSTIIDGYVKQQDMATAIKIFRYMEKNKCKP 588

  Fly   484 DIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGV----LALGCRTQEEARELLEQMH 544
            ::..:..||.....:.|::.|:|....::...|.|::|||..    ||....|.|:|....|.|.
plant   589 NVVTYTSLINGFCCQGDFKMAEETFKEMQLRDLVPNVVTYTTLIRSLAKESSTLEKAVYYWELMM 653

  Fly   545 VAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLRHLHNFHR-------GCAR 602
            ......|......:| ||...|:...|     |:..:|....::.| ....|||       ..|.
plant   654 TNKCVPNEVTFNCLL-QGFVKKTSGKV-----LAEPDGSNHGQSSL-FSEFFHRMKSDGWSDHAA 711

  Fly   603 AIDAR------HPSTKTAAF------KKGHSK-----------FC-----DKYR-LYYEEQGLSG 638
            |.::.      |...|||..      |||.|.           ||     .::| :.:...|..|
plant   712 AYNSALVCLCVHGMVKTACMFQDKMVKKGFSPDPVSFAAILHGFCVVGNSKQWRNMDFCNLGEKG 776

  Fly   639 LKLEDAIAKVKERPYDQFKLPPVNGMEPLKHEQL-KHKTKQ 678
            |::....::|.|:...|   |.:.....:.|..: |..||:
plant   777 LEVAVRYSQVLEQHLPQ---PVICEASTILHAMVEKADTKE 814

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	14/52 (27%)
		PPR_2	182..231	CDD:289786	14/48 (29%)
		PPR	185..215	CDD:279828	7/29 (24%)
		PPR repeat	186..213	CDD:276811	7/26 (27%)
		PPR repeat	219..252	CDD:276811	6/32 (19%)
		PPR_1	252..284	CDD:289614	7/31 (23%)
		PPR_2	256..304	CDD:289786	10/47 (21%)
		PPR repeat	258..287	CDD:276811	5/28 (18%)
		PPR repeat	293..324	CDD:276811	8/30 (27%)
		PPR repeat	330..357	CDD:276811	8/29 (28%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	5/23 (22%)
AT1G52620	NP_175671.1	PPR repeat	101..128	CDD:276811
		PLN03218	<123..>422	CDD:215636	38/165 (23%)
		PPR repeat	136..163	CDD:276811
		PPR repeat	170..198	CDD:276811
		PPR repeat	210..234	CDD:276811
		PPR_2	238..287	CDD:372443	5/16 (31%)
		PPR repeat	242..269	CDD:276811
		PPR repeat	275..304	CDD:276811	9/43 (21%)
		PLN03218	<343..>668	CDD:215636	80/385 (21%)
		PPR repeat	347..374	CDD:276811	7/26 (27%)
		PPR repeat	382..409	CDD:276811	6/30 (20%)
		PPR repeat	417..444	CDD:276811	5/26 (19%)
		PPR repeat	452..479	CDD:276811	7/28 (25%)
		PPR repeat	487..514	CDD:276811	8/43 (19%)
		PPR repeat	522..549	CDD:276811	4/32 (13%)
		PPR repeat	555..584	CDD:276811	3/28 (11%)
		PPR repeat	590..619	CDD:276811	5/28 (18%)
		PPR repeat	625..655	CDD:276811	10/29 (34%)
		PPR_2	712..756	CDD:372443	9/43 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050