DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT1G13630

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001320809.1	Gene:	AT1G13630 / 837924	AraportID:	AT1G13630	Length:	831	Species:	Arabidopsis thaliana

Alignment Length:	768	Identity:	143/768 - (18%)
Similarity:	263/768 - (34%)	Gaps:	247/768 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 EANRNQNPFREEVFEELITAAPKEHQKFKPEKKPKEKSTKKVQDFGDPDTFGDAKVAATE----- 124
            :.:|:.:||...:|    |.:.....|...|..|...||...:.|.....||..|:...|
plant    12 KVSRSLSPFSSLLF----TKSSFSVAKMDDESLPTTNSTSDHRGFYKEILFGMKKIGFREFLHGY 72

  Fly   125 -------DPGDVEEEEFLSNSTRRSKKLKAVEYARQIKD---------------HLKA--NRLNE 165
                   :...|..||.:......|..| :|.:.::::|               |:.|  .|..|
plant    73 HFRGLVSELRHVHVEEIMDELMSESSDL-SVWFFKELRDIYAFRHSSFSTLLVSHVLAGQRRFKE 136

  Fly   166 AIAVLEQRMLKEDRAKPDK----------------YIYNLLISGCAKAGYTRKAFFLYTKMRQRG 214
            ...:|||.:.:|......:                .::::|:...::......:.::..||:.:.
plant   137 LQVILEQLLQEEGSGSASRLCELLSNSFRKWESTGLVWDMLLFLSSRLRMVDDSLYILKKMKDQN 201

  Fly   215 LQVTGGTYTSLFNACANA------------------PSVSDGLAKAQILRENML------EKGYE 255
            |.|:..:|.|:.......                  .:|.|||.:.|.|.:.:|      .|...
plant   202 LNVSTQSYNSVLYHFRETDKMWDVYKEIKDKNEHTYSTVVDGLCRQQKLEDAVLFLRTSEWKDIG 266

  Fly   256 PNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNADTFNFLLQA-CASNSEHGFRHALLTWH 319
            |:|.::|:::..|.:.|.||.|......:::..|..:..:.|.|:.. |...|   ...||....
plant   267 PSVVSFNSIMSGYCKLGFVDMAKSFFCTVLKCGLVPSVYSHNILINGLCLVGS---IAEALELAS 328

  Fly   320 NMLQRGISPDYYSFNAMLRCARDCGF---GDLDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPS 381
            :|.:.|:.||..::|.:.:     ||   |.:....|||..:            |:||..   |.
plant   329 DMNKHGVEPDSVTYNILAK-----GFHLLGMISGAWEVIRDM------------LDKGLS---PD 373

  Fly   382 VEANTTTLPAQIEVATTASELELPNLLLPQP-HLGSLVALEEVTRPHERFLLLGGL--TGFLE-- 441
            |...|..|..|.::......|.|...:|.:. .|.|::...         ::|.||  ||.::
plant   374 VITYTILLCGQCQLGNIDMGLVLLKDMLSRGFELNSIIPCS---------VMLSGLCKTGRIDEA 429

  Fly   442 -----HMKQHNITPDIETFTAML----------------------EVIPPTNA--------AEKQ 471
                 .||...::||:..::.::                      .::|.:..        .:|.
plant   430 LSLFNQMKADGLSPDLVAYSIVIHGLCKLGKFDMALWLYDEMCDKRILPNSRTHGALLLGLCQKG 494

  Fly   472 LLTFVRKI-------GLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG 529
            :|...|.:       |...||..:||:|...:.....|.|.|:..::...|:.|.:.|:..|..|
plant   495 MLLEARSLLDSLISSGETLDIVLYNIVIDGYAKSGCIEEALELFKVVIETGITPSVATFNSLIYG 559

  Fly   530 -CRTQE--EARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEAFLR 591
             |:||.  |||::|                                ::|:|   .||.|:.....
plant   560 YCKTQNIAEARKIL--------------------------------DVIKL---YGLAPSVVSYT 589

  Fly   592 HLHNFHRGCARAIDARHPSTKTAAFKKGHSKFCDKYRLYYEEQGLSGLKLEDAIAKVKERPYDQF 656
            .|.:.:..|                  |::|..|:.|...:.:|
plant   590 TLMDAYANC------------------GNTKSIDELRREMKAEG--------------------- 615

  Fly   657 KLPPVN--------GM-EPLKHEQLKHKTKQRKYIK-KIKIHELKDD--PPKE 697
             :||.|        |: ...|||...|..::|.:.| |..:.:::.:  ||.:
plant   616 -IPPTNVTYSVIFKGLCRGWKHENCNHVLRERIFEKCKQGLRDMESEGIPPDQ 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	9/56 (16%)
		PPR_2	182..231	CDD:289786	7/64 (11%)
		PPR	185..215	CDD:279828	3/29 (10%)
		PPR repeat	186..213	CDD:276811	3/26 (12%)
		PPR repeat	219..252	CDD:276811	9/56 (16%)
		PPR_1	252..284	CDD:289614	9/31 (29%)
		PPR_2	256..304	CDD:289786	11/48 (23%)
		PPR repeat	258..287	CDD:276811	7/28 (25%)
		PPR repeat	293..324	CDD:276811	7/31 (23%)
		PPR repeat	330..357	CDD:276811	7/29 (24%)
		PPR repeat	485..514	CDD:276811	7/28 (25%)
		PPR repeat	552..576	CDD:276811	0/23 (0%)
AT1G13630	NP_001320809.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	1	1.010	-	-		QHG54853
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.970