DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT5G46580

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_199470.1	Gene:	AT5G46580 / 834701	AraportID:	AT5G46580	Length:	711	Species:	Arabidopsis thaliana

Alignment Length:	637	Identity:	130/637 - (20%)
Similarity:	246/637 - (38%)	Gaps:	152/637 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 LVILPATWSCSQNRLLHVRITDQQAGLETKREANRNQNPFREEVFEELITAAPKEHQK---FKPE 95
            |.:.|:.:..|::|.|::..:..:.....:.|....:.|...|..:.|.....::.|.   .||:
plant    25 LFLKPSLFRQSRSRKLNISCSSLKQPKTLEEEPITTKTPSLSEQLKPLSATTLRQEQTQILSKPK 89

  Fly    96 K------KPKEK----STKKVQDFGDPDTFGDAKVAATEDPGDV--EEEEFLS------------ 136
            .      :||..    ..:|...:.......|.:..|.:....:  |:.||||
plant    90 SVWVNPTRPKRSVLSLQRQKRSAYSYNPQIKDLRAFALKLNSSIFTEKSEFLSLLDEIPHPPNRD 154

  Fly   137 ------NSTR------------RSKKLKAVE---YARQIKDHLKANRLNEAIAVLEQRMLKEDRA 180
                  ||.|            :||.|..:|   |...:|. |:..|..:.|..:...|:| |..
plant   155 NALLVLNSLREWQKTHTFFNWVKSKSLFPMETIFYNVTMKS-LRFGRQFQLIEEMALEMVK-DGV 217

  Fly   181 KPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNACANAPSVSDGLAKAQIL 245
            :.|...|:.:|:...:.....||...:.:|.:.||.....||:::.:..:.:..|.:.|:    |
plant   218 ELDNITYSTIITCAKRCNLYNKAIEWFERMYKTGLMPDEVTYSAILDVYSKSGKVEEVLS----L 278

  Fly   246 RENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNADTFNFLLQACASNSEHG 310
            .|..:..|::|:...::.:.|.:|..||.|....:..||....::.|...:|.||:|.....:.|
plant   279 YERAVATGWKPDAIAFSVLGKMFGEAGDYDGIRYVLQEMKSMDVKPNVVVYNTLLEAMGRAGKPG 343

  Fly   311 FRHALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREVIDKIAPSAARKKPVLQLEKGQ 375
            ...:|  ::.||:.|::|:..:..|:::.     :|.....|:.:.......|:|.|:
plant   344 LARSL--FNEMLEAGLTPNEKTLTALVKI-----YGKARWARDALQLWEEMKAKKWPM------- 394

  Fly   376 QDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFL 440
                                     :..|.|.||   ::.:.:.|||..   ||.        |.
plant   395 -------------------------DFILYNTLL---NMCADIGLEEEA---ERL--------FN 420

  Fly   441 EHMKQHNITPDIETFTAMLEVIPPTNAAEKQLLTF--VRKIGLKADIDFFNILIK--KRSMRFDY 501
            :..:.....||..::||||.:......|||.:..|  :.|.|::.::.....|::  .::.|.|
plant   421 DMKESVQCRPDNFSYTAMLNIYGSGGKAEKAMELFEEMLKAGVQVNVMGCTCLVQCLGKAKRID- 484

  Fly   502 ESAKEVLLMIRTA---GLRPDIVTYG----VLALGCRTQEEARELLEQMHVAGIKMNMPILGAML 559
                :|:.:...:   |::||....|    |:|| |.:.|:|.:::                |.|
plant   485 ----DVVYVFDLSIKRGVKPDDRLCGCLLSVMAL-CESSEDAEKVM----------------ACL 528

  Fly   560 RQGCANKSF-SYVNEIIQLSLE-EGLKPNEAFLRHLHNFHRGCARAIDARHP 609
            .:  |||.. ::||.|:....| |.:|  |.|...::      |..::||.|
plant   529 ER--ANKKLVTFVNLIVDEKTEYETVK--EEFKLVIN------ATQVEARRP 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	9/38 (24%)
		PPR_2	182..231	CDD:289786	10/48 (21%)
		PPR	185..215	CDD:279828	5/29 (17%)
		PPR repeat	186..213	CDD:276811	5/26 (19%)
		PPR repeat	219..252	CDD:276811	6/32 (19%)
		PPR_1	252..284	CDD:289614	7/31 (23%)
		PPR_2	256..304	CDD:289786	13/47 (28%)
		PPR repeat	258..287	CDD:276811	7/28 (25%)
		PPR repeat	293..324	CDD:276811	8/30 (27%)
		PPR repeat	330..357	CDD:276811	3/26 (12%)
		PPR repeat	485..514	CDD:276811	4/30 (13%)
		PPR repeat	552..576	CDD:276811	8/24 (33%)
AT5G46580	NP_199470.1	PPR repeat	155..179	CDD:276811	3/23 (13%)
		PPR repeat	188..215	CDD:276811	7/28 (25%)
		PLN03218	<211..>515	CDD:215636	76/367 (21%)
		PPR repeat	221..250	CDD:276811	5/28 (18%)
		PPR repeat	258..285	CDD:276811	6/30 (20%)
		PPR repeat	291..320	CDD:276811	7/28 (25%)
		PPR repeat	326..354	CDD:276811	7/29 (24%)
		PPR repeat	361..390	CDD:276811	3/33 (9%)
		PPR repeat	396..425	CDD:276811	10/42 (24%)
		PPR repeat	432..461	CDD:276811	8/28 (29%)
		PPR repeat	467..496	CDD:276811	4/33 (12%)
		PPR repeat	502..530	CDD:276811	9/44 (20%)
		Smr	611..691	CDD:413405
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000