DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT5G42310

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_199046.1	Gene:	AT5G42310 / 834236	AraportID:	AT5G42310	Length:	709	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	114/569 - (20%)
Similarity:	211/569 - (37%)	Gaps:	134/569 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 PDTFGDAKVAATEDPGDVEEE-EFLSNSTRRSKKLKAVEYARQIKDHLKANRLNEAIAVLEQRML 175
            |.|: :|.:.|.....|:|:. ..::...:...:...|.|:..|:...::|:::..:.:...:.:
plant   197 PLTY-NALIGACARNNDIEKALNLIAKMRQDGYQSDFVNYSLVIQSLTRSNKIDSVMLLRLYKEI 260

  Fly   176 KEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNACANAPSVSDGLA 240
            :.|:.:.|..:.|.:|.|.||:|...||..|....:..||.....|..|:.:|.|:    |....
plant   261 ERDKLELDVQLVNDIIMGFAKSGDPSKALQLLGMAQATGLSAKTATLVSIISALAD----SGRTL 321

  Fly   241 KAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNADTFNFLLQACA- 304
            :|:.|.|.:.:.|.:|..:.|||::|.|.:.|.:..|..:..||.:|.:..:..|::.|:.|..
plant   322 EAEALFEELRQSGIKPRTRAYNALLKGYVKTGPLKDAESMVSEMEKRGVSPDEHTYSLLIDAYVN 386

  Fly   305 --------------------------SNSEHGFR------------------------------- 312
                                      |....|||
plant   387 AGRWESARIVLKEMEAGDVQPNSFVFSRLLAGFRDRGEWQKTFQVLKEMKSIGVKPDRQFYNVVI 451

  Fly   313 ----------HALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREVIDKIAPSAARKKP 367
                      ||:.|:..||..||.||..::|.::.|  .|..|     |.::.:....|..::.
plant   452 DTFGKFNCLDHAMTTFDRMLSEGIEPDRVTWNTLIDC--HCKHG-----RHIVAEEMFEAMERRG 509

  Fly   368 VLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLL 432
            .|                        ..|||.      |:::..  .|.....:::.|      |
plant   510 CL------------------------PCATTY------NIMINS--YGDQERWDDMKR------L 536

  Fly   433 LGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAAEK--QLLTFVRKIGLKADIDFFNILIKKR 495
            ||       .||...|.|::.|.|.:::|...:.....  :.|..::.:|||.....:|.||...
plant   537 LG-------KMKSQGILPNVVTHTTLVDVYGKSGRFNDAIECLEEMKSVGLKPSSTMYNALINAY 594

  Fly   496 SMRFDYESAKEVLLMIRTAGLRPDIVTYGVL--ALG-CRTQEEARELLEQMHVAGIKMNMPILGA 557
            :.|...|.|.....::.:.||:|.::....|  |.| .|...||..:|:.|...|:|.::.....
plant   595 AQRGLSEQAVNAFRVMTSDGLKPSLLALNSLINAFGEDRRDAEAFAVLQYMKENGVKPDVVTYTT 659

  Fly   558 MLRQGCANKSFSYVNEIIQLSLEEGLKPN---EAFLRHLHNFHRGCARA 603
            :::.......|..|..:.:..:..|.||:   .:.||....:.:...||
plant   660 LMKALIRVDKFQKVPVVYEEMIMSGCKPDRKARSMLRSALRYMKQTLRA 708

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	6/38 (16%)
		PPR_2	182..231	CDD:289786	15/48 (31%)
		PPR	185..215	CDD:279828	9/29 (31%)
		PPR repeat	186..213	CDD:276811	9/26 (35%)
		PPR repeat	219..252	CDD:276811	8/32 (25%)
		PPR_1	252..284	CDD:289614	9/31 (29%)
		PPR_2	256..304	CDD:289786	14/47 (30%)
		PPR repeat	258..287	CDD:276811	9/28 (32%)
		PPR repeat	293..324	CDD:276811	12/98 (12%)
		PPR repeat	330..357	CDD:276811	5/26 (19%)
		PPR repeat	485..514	CDD:276811	6/28 (21%)
		PPR repeat	552..576	CDD:276811	2/23 (9%)
AT5G42310	NP_199046.1	PPR_2	199..242	CDD:289786	8/43 (19%)
		PPR	199..231	CDD:273253	5/32 (16%)
		PPR repeat	199..226	CDD:276811	5/27 (19%)
		PPR repeat	232..263	CDD:276811	4/30 (13%)
		PPR repeat	273..298	CDD:276811	9/24 (38%)
		PPR repeat	306..333	CDD:276811	8/30 (27%)
		PPR_2	309..351	CDD:289786	14/45 (31%)
		PPR_2	337..386	CDD:289786	14/48 (29%)
		PPR repeat	339..368	CDD:276811	9/28 (32%)
		PPR	340..374	CDD:273253	10/33 (30%)
		PPR_1	368..401	CDD:289614	4/32 (13%)
		PPR_2	372..419	CDD:289786	4/46 (9%)
		PPR repeat	374..401	CDD:276811	3/26 (12%)
		PPR repeat	409..437	CDD:276811	4/27 (15%)
		PPR_2	442..491	CDD:289786	11/50 (22%)
		PPR	447..478	CDD:273253	7/30 (23%)
		PPR repeat	447..473	CDD:276811	5/25 (20%)
		PPR_1	473..506	CDD:289614	10/39 (26%)
		PPR_2	477..524	CDD:289786	13/85 (15%)
		PPR repeat	481..508	CDD:276811	6/33 (18%)
		PPR repeat	514..543	CDD:276811	11/49 (22%)
		PPR	516..549	CDD:273253	11/53 (21%)
		PPR_1	543..576	CDD:289614	6/32 (19%)
		PPR_2	547..596	CDD:289786	11/48 (23%)
		PPR repeat	549..577	CDD:276811	4/27 (15%)
		PPR repeat	584..613	CDD:276811	6/28 (21%)
		PPR	586..618	CDD:273253	8/31 (26%)
		PPR_2	617..664	CDD:289786	11/46 (24%)
		PPR repeat	619..648	CDD:276811	8/28 (29%)
		PPR	623..654	CDD:273253	10/30 (33%)
		PPR_2	652..>688	CDD:289786	4/35 (11%)
		PPR repeat	654..683	CDD:276811	2/28 (7%)
		PPR	655..688	CDD:273253	4/32 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960