DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT5G02860

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_001332236.1	Gene:	AT5G02860 / 831761	AraportID:	AT5G02860	Length:	819	Species:	Arabidopsis thaliana

Alignment Length:	593	Identity:	127/593 - (21%)
Similarity:	233/593 - (39%)	Gaps:	117/593 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 NQNPFRE--EVFEELITAAPKEHQKFKPE--------------KKPKEKSTKKVQ----DFGDPD 113
            |...:||  .||:::      |....||.              ..|..|.|..|:    |...||
plant   220 NSGRYREAVNVFKKM------EEDGCKPTLITYNVILNVFGKMGTPWNKITSLVEKMKSDGIAPD 278

  Fly   114 TFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKA-------VEYARQIKDHLKANRLNEAIAVLE 171
            .:....:......|.:.:|     :.:..:::||       |.|...:..:.|::|..||:.||.
plant   279 AYTYNTLITCCKRGSLHQE-----AAQVFEEMKAAGFSYDKVTYNALLDVYGKSHRPKEAMKVLN 338

  Fly   172 QRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNACANAPSVS 236
            :.:|  :...|....||.|||..|:.|...:|..|..:|.::|.:....|||:|.:....|..|.
plant   339 EMVL--NGFSPSIVTYNSLISAYARDGMLDEAMELKNQMAEKGTKPDVFTYTTLLSGFERAGKVE 401

  Fly   237 DGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEM----------------- 284
            ..::    :.|.|...|.:||:..:||.||.||..|.......:.||:
plant   402 SAMS----IFEEMRNAGCKPNICTFNAFIKMYGNRGKFTEMMKIFDEINVCGLSPDIVTWNTLLA 462

  Fly   285 ------MERQL-----EL-------NADTFNFLLQA---CASNSEHGFRHALLTWHNMLQRGISP 328
                  |:.::     |:       ..:|||.|:.|   |.|     |..|:..:..||..|::|
plant   463 VFGQNGMDSEVSGVFKEMKRAGFVPERETFNTLISAYSRCGS-----FEQAMTVYRRMLDAGVTP 522

  Fly   329 DYYSFNAMLRCARDCGFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQI 393
            |..::|.:|......|      |.|..:|:         :.::|.|:      .:.|..|..:.:
plant   523 DLSTYNTVLAALARGG------MWEQSEKV---------LAEMEDGR------CKPNELTYCSLL 566

  Fly   394 EVATTASELELPNLLLPQPHLGSL----VALEEVTRPHERFLLLGGLTGFLEHMKQHNITPDIET 454
            .......|:.|.:.|..:.:.|.:    |.|:.:.....:..||.........:|:...:|||.|
plant   567 HAYANGKEIGLMHSLAEEVYSGVIEPRAVLLKTLVLVCSKCDLLPEAERAFSELKERGFSPDITT 631

  Fly   455 FTAMLEVIPPTNAAEKQ--LLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLR 517
            ..:|:.:........|.  :|.::::.|....:..:|.|:...|...|:..::|:|..|...|::
plant   632 LNSMVSIYGRRQMVAKANGVLDYMKERGFTPSMATYNSLMYMHSRSADFGKSEEILREILAKGIK 696

  Fly   518 PDIVTYG-VLALGCRT--QEEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSL 579
            |||::|. |:...||.  ..:|..:..:|..:||..::......:....|:..|.....:::..:
plant   697 PDIISYNTVIYAYCRNTRMRDASRIFSEMRNSGIVPDVITYNTFIGSYAADSMFEEAIGVVRYMI 761

  Fly   580 EEGLKPNE 587
            :.|.:||:
plant   762 KHGCRPNQ 769

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	13/38 (34%)
		PPR_2	182..231	CDD:289786	16/48 (33%)
		PPR	185..215	CDD:279828	10/29 (34%)
		PPR repeat	186..213	CDD:276811	10/26 (38%)
		PPR repeat	219..252	CDD:276811	8/32 (25%)
		PPR_1	252..284	CDD:289614	11/31 (35%)
		PPR_2	256..304	CDD:289786	18/85 (21%)
		PPR repeat	258..287	CDD:276811	10/51 (20%)
		PPR repeat	293..324	CDD:276811	11/33 (33%)
		PPR repeat	330..357	CDD:276811	5/26 (19%)
		PPR repeat	485..514	CDD:276811	7/28 (25%)
		PPR repeat	552..576	CDD:276811	2/23 (9%)
AT5G02860	NP_001332236.1	PPR repeat	142..165	CDD:276811
		PPR_2	174..220	CDD:372443	127/593 (21%)
		PPR repeat	178..202	CDD:276811
		PPR_3	199..256	CDD:316342	8/41 (20%)
		PPR repeat	210..237	CDD:276811	6/22 (27%)
		PPR repeat	243..273	CDD:276811	4/29 (14%)
		PPR repeat	281..308	CDD:276811	3/31 (10%)
		PLN03218	<282..>781	CDD:215636	112/525 (21%)
		PPR repeat	316..343	CDD:276811	8/28 (29%)
		PPR repeat	349..378	CDD:276811	10/28 (36%)
		PPR repeat	384..411	CDD:276811	7/30 (23%)
		PPR repeat	419..444	CDD:276811	7/24 (29%)
		PPR repeat	454..482	CDD:276811	2/27 (7%)
		PPR repeat	489..518	CDD:276811	11/33 (33%)
		PPR_2	491..536	CDD:372443	16/49 (33%)
		PPR repeat	524..552	CDD:276811	6/42 (14%)
		PPR repeat	559..584	CDD:276811	4/24 (17%)
		PPR repeat	596..623	CDD:276811	4/26 (15%)
		PPR repeat	631..658	CDD:276811	4/26 (15%)
		PPR repeat	666..693	CDD:276811	7/26 (27%)
		PPR repeat	701..728	CDD:276811	6/26 (23%)
		PPR repeat	734..763	CDD:276811	2/28 (7%)
		PPR repeat	769..796	CDD:276811	0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.960