DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and SVR7

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_193372.6	Gene:	SVR7 / 827333	AraportID:	AT4G16390	Length:	702	Species:	Arabidopsis thaliana

Alignment Length:	596	Identity:	125/596 - (20%)
Similarity:	210/596 - (35%)	Gaps:	176/596 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 NRLNEAIAVLEQRMLKEDRAKPDK--YIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYT 223
            |..|...|.|....|.| ..||.:  .:||:.:....|:....|:..|:.:|.:||::....|:|
plant   151 NMTNPETAPLVLNNLLE-TMKPSREVILYNVTMKVFRKSKDLEKSEKLFDEMLERGIKPDNATFT 214

  Fly   224 SLFNACANAPSVSDGLAKAQI-LRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMER 287
            ::. :||.    .:|:.|..: ..|.|...|.||:.....|||.||||.|:||.|..|.|.....
plant   215 TII-SCAR----QNGVPKRAVEWFEKMSSFGCEPDNVTMAAMIDAYGRAGNVDMALSLYDRARTE 274

  Fly   288 QLELNADTFNFLLQ---------ACASNSEH----GFR--------------------HALLTWH 319
            :..::|.||:.|::         .|.:..|.    |.:                    .|.:.:.
plant   275 KWRIDAVTFSTLIRIYGVSGNYDGCLNIYEEMKALGVKPNLVIYNRLIDSMGRAKRPWQAKIIYK 339

  Fly   320 NMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREVIDKIAPSAARKKPVLQLEKGQQDDLPSVEA 384
            :::..|.:|::.::.|::|......:||        |.:|.....|:..|.|.....:.|.|:.|
plant   340 DLITNGFTPNWSTYAALVRAYGRARYGD--------DALAIYREMKEKGLSLTVILYNTLLSMCA 396

  Fly   385 NTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLEHMKQ-HNI 448
            :...:....|:                                            .:.||. ...
plant   397 DNRYVDEAFEI--------------------------------------------FQDMKNCETC 417

  Fly   449 TPDIETFTAMLEVIP---PTNAAEKQLLTFVRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLM 510
            .||..||::::.|..   ..:.||..||. :|:.|.:..:.....:|:      .|..||:|..:
plant   418 DPDSWTFSSLITVYACSGRVSEAEAALLQ-MREAGFEPTLFVLTSVIQ------CYGKAKQVDDV 475

  Fly   511 IRT------AGLRPDIVTYGVLALGCRTQ---EEARELLEQMHVAGIKMNMPILGAMLRQGCANK 566
            :||      .|:.||....|.| |...||   ||..:|:..:..|..|:...:...:..|.|...
plant   476 VRTFDQVLELGITPDDRFCGCL-LNVMTQTPSEEIGKLIGCVEKAKPKLGQVVKMLVEEQNCEEG 539

  Fly   567 SF-----------------SYVN----------------EIIQLSLE----EGLKPNEA--FLRH 592
            .|                 :|:|                ||:||.||    .||:...|  :..|
plant   540 VFKKEASELIDSIGSDVKKAYLNCLIDLCVNLNKLERACEILQLGLEYDIYTGLQSKSATQWSLH 604

  Fly   593 LHNFHRGCA-------------RAIDARHPSTKTAAFKKGHSKFCDKYRLYYEEQGLSGL---KL 641
            |.:...|.|             .|:::............||.|.      .|.::||:.:   .|
plant   605 LKSLSLGAALTALHVWMNDLSEAALESGEEFPPLLGINTGHGKH------KYSDKGLAAVFESHL 663

  Fly   642 EDAIAKVKERP 652
            ::..|...|.|
plant   664 KELNAPFHEAP 674

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	10/36 (28%)
		PPR_2	182..231	CDD:289786	12/50 (24%)
		PPR	185..215	CDD:279828	7/29 (24%)
		PPR repeat	186..213	CDD:276811	6/26 (23%)
		PPR repeat	219..252	CDD:276811	8/33 (24%)
		PPR_1	252..284	CDD:289614	16/31 (52%)
		PPR_2	256..304	CDD:289786	18/56 (32%)
		PPR repeat	258..287	CDD:276811	13/28 (46%)
		PPR repeat	293..324	CDD:276811	8/63 (13%)
		PPR repeat	330..357	CDD:276811	4/26 (15%)
		PPR repeat	485..514	CDD:276811	7/34 (21%)
		PPR repeat	552..576	CDD:276811	7/56 (13%)
SVR7	NP_193372.6	PPR_2	175..219	CDD:289786	10/44 (23%)
		PPR	176..209	CDD:273253	8/32 (25%)
		PPR repeat	177..204	CDD:276811	6/26 (23%)
		PPR_2	208..257	CDD:289786	16/53 (30%)
		PPR repeat	210..239	CDD:276811	8/33 (24%)
		PPR	212..244	CDD:273253	10/36 (28%)
		PPR_1	240..270	CDD:289614	15/29 (52%)
		PPR repeat	245..270	CDD:276811	12/24 (50%)
		PPR_2	279..327	CDD:289786	7/47 (15%)
		PPR	281..314	CDD:273253	6/32 (19%)
		PPR repeat	282..309	CDD:276811	5/26 (19%)
		PPR_2	313..362	CDD:289786	5/48 (10%)
		PPR repeat	315..344	CDD:276811	1/28 (4%)
		PPR repeat	350..379	CDD:276811	7/36 (19%)
		PPR	352..385	CDD:273253	9/40 (23%)
		PPR_1	379..412	CDD:289614	6/76 (8%)
		PPR_2	384..432	CDD:289786	11/91 (12%)
		PPR repeat	385..412	CDD:276811	4/70 (6%)
		PPR_2	419..468	CDD:289786	13/55 (24%)
		PPR repeat	421..449	CDD:276811	7/28 (25%)
		PPR	423..455	CDD:273253	9/32 (28%)
		PPR repeat	456..484	CDD:276811	7/33 (21%)
		PPR	457..491	CDD:273253	9/39 (23%)
		PPR repeat	551..582	CDD:276811	4/30 (13%)
		SMR	600..672	CDD:214676	13/77 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000