DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4611 and MEE40

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_190938.1	Gene:	MEE40 / 824537	AraportID:	AT3G53700	Length:	754	Species:	Arabidopsis thaliana

Alignment Length:	657	Identity:	141/657 - (21%)
Similarity:	261/657 - (39%)	Gaps:	113/657 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 NRLLHVRITDQQAGLETKREANRNQNPFREEV--FEELITAAPKEHQKFKPEKKPKEKSTKKVQD 108
            ||:|::.:......|.....|..:....:.:|  |..||.|..:.|| .:|       :...::|
plant   158 NRMLNLLVDGNSLKLVEISHAKMSVWGIKPDVSTFNVLIKALCRAHQ-LRP-------AILMLED 214

  Fly   109 FGDPDTFGDAKVAATEDPGDVEEEEFLSNSTRRSKKLKAVEYARQ---------IKDHLKANRLN 164
            ........|.|...|...|.:||.: |..:.|..:::  ||:...         :....|..|:.
plant   215 MPSYGLVPDEKTFTTVMQGYIEEGD-LDGALRIREQM--VEFGCSWSNVSVNVIVHGFCKEGRVE 276

  Fly   165 EAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLFNAC 229
            :|:..: |.|..:|...||:|.:|.|::|..|||:.:.|..:...|.|.|......||.|:.:..
plant   277 DALNFI-QEMSNQDGFFPDQYTFNTLVNGLCKAGHVKHAIEIMDVMLQEGYDPDVYTYNSVISGL 340

  Fly   230 ANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGDVDTAYMLADEMMERQLELNAD 294
            .....|.:.:   ::| :.|:.:...||...||.:|....:...|:.|..||..:..:.:..:..
plant   341 CKLGEVKEAV---EVL-DQMITRDCSPNTVTYNTLISTLCKENQVEEATELARVLTSKGILPDVC 401

  Fly   295 TFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLRCARDCGFGDLDSMREVIDKIA 359
            |||.|:|.......|  |.|:..:..|..:|..||.:::|.:           :||:
plant   402 TFNSLIQGLCLTRNH--RVAMELFEEMRSKGCEPDEFTYNML-----------IDSL-------- 445

  Fly   360 PSAARKKPVLQLEKGQQDDLPSVEANTTTLPAQIEVATTASELELPNLLLPQPHLGSLVALEEVT 424
                       ..||:.|:       ...:..|:|::..|..:...|.|:.    |...|  ..|
plant   446 -----------CSKGKLDE-------ALNMLKQMELSGCARSVITYNTLID----GFCKA--NKT 486

  Fly   425 RPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAAE--KQLLTFVRKIGLKADIDF 487
            |..|.         ..:.|:.|.::.:..|:..:::.:..:...|  .||:..:...|.|.|...
plant   487 REAEE---------IFDEMEVHGVSRNSVTYNTLIDGLCKSRRVEDAAQLMDQMIMEGQKPDKYT 542

  Fly   488 FNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-CRT--QEEARELLEQMHVAGIK 549
            :|.|:.......|.:.|.:::..:.:.|..|||||||.|..| |:.  .|.|.:||..:.:.||.
plant   543 YNSLLTHFCRGGDIKKAADIVQAMTSNGCEPDIVTYGTLISGLCKAGRVEVASKLLRSIQMKGIN 607

  Fly   550 MN----MPILGAMLRQGCANKSFSYVNEIIQLSLEEGLKPNEA-----FLRHLHNFHRGCARAID 605
            :.    .|::..:.|:....::.:...|:    ||:...|.:|     ..|.|.|.......|:|
plant   608 LTPHAYNPVIQGLFRKRKTTEAINLFREM----LEQNEAPPDAVSYRIVFRGLCNGGGPIREAVD 668

  Fly   606 ARHPSTKTAAFKKGHSKFCDKY-RLYYEEQGLSGLKLEDAIAK-----VKERPYDQFKLPPVNGM 664
                 ......:||   |..:: .||...:||..|.:|:.:.|     :::..:.:.::..|.|:
plant   669 -----FLVELLEKG---FVPEFSSLYMLAEGLLTLSMEETLVKLVNMVMQKARFSEEEVSMVKGL 725

  Fly   665 EPLKHEQ 671
            ..::..|
plant   726 LKIRKFQ 732

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	12/38 (32%)
		PPR_2	182..231	CDD:289786	16/48 (33%)
		PPR	185..215	CDD:279828	10/29 (34%)
		PPR repeat	186..213	CDD:276811	8/26 (31%)
		PPR repeat	219..252	CDD:276811	6/32 (19%)
		PPR_1	252..284	CDD:289614	9/31 (29%)
		PPR_2	256..304	CDD:289786	14/47 (30%)
		PPR repeat	258..287	CDD:276811	7/28 (25%)
		PPR repeat	293..324	CDD:276811	9/30 (30%)
		PPR repeat	330..357	CDD:276811	3/26 (12%)
		PPR repeat	485..514	CDD:276811	4/28 (14%)
		PPR repeat	552..576	CDD:276811	3/23 (13%)
MEE40	NP_190938.1	PPR repeat	89..112	CDD:276811
		PPR repeat	118..142	CDD:276811
		PPR_2	152..201	CDD:289786	10/42 (24%)
		PPR repeat	157..183	CDD:276811	5/24 (21%)
		PPR_1	184..216	CDD:289614	9/39 (23%)
		PPR_2	187..234	CDD:289786	12/54 (22%)
		PPR repeat	191..218	CDD:276811	8/34 (24%)
		PPR_1	219..251	CDD:289614	8/34 (24%)
		PPR_2	222..271	CDD:289786	10/51 (20%)
		PPR repeat	224..253	CDD:276811	8/31 (26%)
		PPR_1	254..286	CDD:289614	4/32 (13%)
		PPR_2	260..307	CDD:289786	12/47 (26%)
		PPR repeat	261..289	CDD:276811	5/28 (18%)
		PPR_1	289..321	CDD:289614	11/31 (35%)
		PPR_2	293..342	CDD:289786	16/48 (33%)
		PPR repeat	297..324	CDD:276811	8/26 (31%)
		PPR_1	324..356	CDD:289614	6/35 (17%)
		PPR_2	328..377	CDD:289786	11/52 (21%)
		PPR repeat	330..359	CDD:276811	6/32 (19%)
		PPR_1	359..387	CDD:289614	7/27 (26%)
		PPR repeat	367..394	CDD:276811	7/26 (27%)
		PPR_1	394..427	CDD:289614	8/34 (24%)
		PPR_2	398..446	CDD:289786	15/79 (19%)
		PPR repeat	402..429	CDD:276811	9/28 (32%)
		PPR_1	429..462	CDD:289614	10/69 (14%)
		PPR repeat	437..464	CDD:276811	8/63 (13%)
		PPR_1	465..497	CDD:289614	8/46 (17%)
		PPR_2	469..517	CDD:289786	10/62 (16%)
		PPR repeat	470..499	CDD:276811	8/43 (19%)
		PPR_1	499..531	CDD:289614	5/31 (16%)
		PPR_2	504..552	CDD:289786	9/47 (19%)
		PPR repeat	505..534	CDD:276811	4/28 (14%)
		PPR_2	538..587	CDD:289786	15/48 (31%)
		PPR repeat	540..569	CDD:276811	4/28 (14%)
		PPR	541..575	CDD:273253	6/33 (18%)
		PPR_1	569..604	CDD:289614	15/34 (44%)
		PPR_2	573..658	CDD:289786	25/88 (28%)
		PPR repeat	575..604	CDD:276811	12/28 (43%)
		PPR repeat	610..638	CDD:276811	3/31 (10%)
		PPR	611..643	CDD:273253	5/35 (14%)
		PPR repeat	646..676	CDD:276811	6/34 (18%)
		PPR repeat	682..711	CDD:276811	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960