DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4611 and AT3G22470

DIOPT Version :9

Sequence 1:	NP_647949.1	Gene:	CG4611 / 38601	FlyBaseID:	FBgn0035591	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_188886.1	Gene:	AT3G22470 / 821818	AraportID:	AT3G22470	Length:	619	Species:	Arabidopsis thaliana

Alignment Length:	441	Identity:	103/441 - (23%)
Similarity:	185/441 - (41%)	Gaps:	82/441 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 RLNEAIAVLEQRMLKEDRAKPDKYIYNLLISGCAKAGYTRKAFFLYTKMRQRGLQVTGGTYTSLF 226
            |::||: ||..||: |...:||:..|..:::...|:|.:..|..|:.||.:|.::.:...|:.:.
plant   190 RVSEAL-VLIDRMV-EYGFQPDEVTYGPVLNRLCKSGNSALALDLFRKMEERNIKASVVQYSIVI 252

  Fly   227 NACANAPSVSDGLAKAQILRENMLEKGYEPNVKNYNAMIKAYGRCGD---VDTAYMLADEMMERQ 288
            ::.....|..|.|:    |...|..||.:.:|..|:::|.  |.|.|   .|.|.||. ||:.|.
plant   253 DSLCKDGSFDDALS----LFNEMEMKGIKADVVTYSSLIG--GLCNDGKWDDGAKMLR-EMIGRN 310

  Fly   289 LELNADTFNFLLQACASNSEHGFRHALLTWHNMLQRGISPDYYSFNAMLR--CARDCGFGDLDSM 351
            :..:..||:.|:....  .|.....|...::.|:.|||:||..::|:::.  |..:|    |...
plant   311 IIPDVVTFSALIDVFV--KEGKLLEAKELYNEMITRGIAPDTITYNSLIDGFCKENC----LHEA 369

  Fly   352 REVIDKIAPSAARKKPVLQLEKGQQDDLP--SVEANTTTLPAQIE-----VATTASELELPN--- 406
            .::.|            |.:.||.:.|:.  |:..|:.....:::     ....:|:..:||
plant   370 NQMFD------------LMVSKGCEPDIVTYSILINSYCKAKRVDDGMRLFREISSKGLIPNTIT 422

  Fly   407 ---LLLPQPHLGSLVALEEVTRPHERFLLLGGLTGFLEHMKQHNITPDIETFTAMLEVIPPTNAA 468
               |:|.....|.|.|.:|:                .:.|....:.|.:.|:..:|:.:......
plant   423 YNTLVLGFCQSGKLNAAKEL----------------FQEMVSRGVPPSVVTYGILLDGLCDNGEL 471

  Fly   469 EKQLLTF--VRKIGLKADIDFFNILIKKRSMRFDYESAKEVLLMIRTAGLRPDIVTYGVLALG-C 530
            .|.|..|  ::|..:...|..:||:|.........:.|..:...:...|::||:|||.|:..| |
plant   472 NKALEIFEKMQKSRMTLGIGIYNIIIHGMCNASKVDDAWSLFCSLSDKGVKPDVVTYNVMIGGLC 536

  Fly   531 R--TQEEARELLEQMHVAGIKMNMPILGAMLRQGCANKSFSYVNEIIQLSL 579
            :  :..||..|..:|.               ..||....|:| |.:|:..|
plant   537 KKGSLSEADMLFRKMK---------------EDGCTPDDFTY-NILIRAHL 571

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4611	NP_647949.1	PPR_2	<157..196	CDD:289786	11/33 (33%)
		PPR_2	182..231	CDD:289786	11/48 (23%)
		PPR	185..215	CDD:279828	8/29 (28%)
		PPR repeat	186..213	CDD:276811	7/26 (27%)
		PPR repeat	219..252	CDD:276811	6/32 (19%)
		PPR_1	252..284	CDD:289614	12/34 (35%)
		PPR_2	256..304	CDD:289786	16/50 (32%)
		PPR repeat	258..287	CDD:276811	12/31 (39%)
		PPR repeat	293..324	CDD:276811	6/30 (20%)
		PPR repeat	330..357	CDD:276811	4/28 (14%)
		PPR repeat	485..514	CDD:276811	5/28 (18%)
		PPR repeat	552..576	CDD:276811	5/23 (22%)
AT3G22470	NP_188886.1	PPR repeat	73..99	CDD:276811
		PPR_2	104..151	CDD:289786
		PPR repeat	107..134	CDD:276811
		PPR_1	135..167	CDD:289614
		PPR_2	138..186	CDD:289786
		PPR repeat	142..169	CDD:276811
		PPR_1	172..202	CDD:289614	6/12 (50%)
		PPR repeat	175..204	CDD:276811	7/15 (47%)
		PPR_2	208..257	CDD:289786	11/48 (23%)
		PPR_3	210..243	CDD:290526	8/32 (25%)
		PPR repeat	212..239	CDD:276811	7/26 (27%)
		PPR_1	239..272	CDD:289614	6/36 (17%)
		PPR_2	244..292	CDD:289786	12/53 (23%)
		PPR repeat	248..274	CDD:276811	6/29 (21%)
		PPR_1	274..306	CDD:289614	12/34 (35%)
		PPR repeat	282..309	CDD:276811	11/29 (38%)
		PPR_2	313..362	CDD:289786	12/50 (24%)
		PPR	316..350	CDD:273253	10/35 (29%)
		PPR repeat	317..344	CDD:276811	6/28 (21%)
		PPR_1	344..377	CDD:289614	11/48 (23%)
		PPR_2	348..397	CDD:289786	13/64 (20%)
		PPR repeat	352..379	CDD:276811	6/42 (14%)
		PPR_1	379..410	CDD:289614	5/30 (17%)
		PPR repeat	385..414	CDD:276811	2/28 (7%)
		PPR_1	414..447	CDD:289614	8/48 (17%)
		PPR_2	418..467	CDD:289786	12/64 (19%)
		PPR repeat	420..449	CDD:276811	7/44 (16%)
		PPR_1	449..482	CDD:289614	6/32 (19%)
		PPR repeat	455..484	CDD:276811	5/28 (18%)
		PPR	492..525	CDD:273253	6/32 (19%)
		PPR repeat	492..518	CDD:276811	4/25 (16%)
		PPR_2	493..537	CDD:289786	12/43 (28%)
		PPR_1	519..552	CDD:289614	12/32 (38%)
		PPR_2	523..570	CDD:289786	18/62 (29%)
		PPR repeat	525..554	CDD:276811	10/43 (23%)
		PPR repeat	560..587	CDD:276811	5/13 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I2129
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960